Title : Chemoselective Hydrogenation of 6-Alkynyl-3-fluoro-2-pyridinaldoximes: Access to First-in-Class 6-Alkyl-3-Fluoro-2-pyridinaldoxime Scaffolds as New Reactivators of Sarin-Inhibited Human Acetylcholinesterase with Increased Blood-Brain Barrier Permeability - Yerri_2020_Chemistry_26_15035 |
Author(s) : Yerri J , Dias J , Nimmakayala MR , Razafindrainibe F , Courageux C , Gastellier AJ , Jegoux J , Coisne C , Landry C , Gosselet F , Hachani J , Goossens JF , Dehouck MP , Nachon F , Baati R |
Ref : Chemistry , 26 :15035 , 2020 |
Abstract : |
PubMedSearch : Yerri_2020_Chemistry_26_15035 |
PubMedID: 32633095 |
Title : Efficacy Assessment of an Uncharged Reactivator of NOP-Inhibited Acetylcholinesterase Based on Tetrahydroacridine Pyridine-Aldoxime Hybrid in Mouse Compared to Pralidoxime - Calas_2020_Biomolecules_10_ |
Author(s) : Calas AG , Hanak AS , Jaffre N , Nervo A , Dias J , Rousseau C , Courageux C , Brazzolotto X , Villa P , Obrecht A , Goossens JF , Landry C , Hachani J , Gosselet F , Dehouck MP , Yerri J , Kliachyna M , Baati R , Nachon F |
Ref : Biomolecules , 10 : , 2020 |
Abstract : |
PubMedSearch : Calas_2020_Biomolecules_10_ |
PubMedID: 32512884 |