Kovach IM

General

Full name : Kovach Ildiko M

First name : Ildiko M

Mail : Dept of Chemistry, The Catholic University of America, 620 Michigan Avenue, NE, Washington, DC 20064

Zip Code :

City :

Country : USA

Email : kovach@cua.edu

Phone : 202-319-6550

Fax : 202-319-5381

Website :

Directory :

Comment

References (17)

Title : Poster (17) Short, strong hydrogen bonds at the active site of cholinesterases: H-NMR studies. -
Author(s) : Kovach IM , Viragh C , Reddy PM , Massiah MA , Mildvan AS , Johnson JL , Rosenberry TL
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :329 , 2004
PubMedID:

Title : Short, Strong Hydrogen Bonds at the Active Site of Human Acetylcholinesterase: Proton NMR Studies - Massiah_2001_Biochemistry_40_5682
Author(s) : Massiah MA , Viragh C , Reddy PM , Kovach IM , Johnson J , Rosenberry TL , Mildvan AS
Ref : Biochemistry , 40 :5682 , 2001
Abstract :
PubMedSearch : Massiah_2001_Biochemistry_40_5682
PubMedID: 11341833

Title : Molecular dynamics study of active-site interactions with tetracoordinate transients in acetylcholinesterase and its mutants - Enyedy_2001_Biochem.J_353_645
Author(s) : Enyedy IJ , Kovach IM , Bencsura A
Ref : Biochemical Journal , 353 :645 , 2001
Abstract :
PubMedSearch : Enyedy_2001_Biochem.J_353_645
PubMedID: 11171062

Title : NMR evidence for a short, strong hydrogen bond at the active site of a cholinesterase - Viragh_2000_Biochemistry_39_16200
Author(s) : Viragh C , Harris TK , Reddy PM , Massiah MA , Mildvan AS , Kovach IM
Ref : Biochemistry , 39 :16200 , 2000
Abstract :
PubMedSearch : Viragh_2000_Biochemistry_39_16200
PubMedID: 11123949

Title : Small Molecular Products of Dealkylation in Soman-Inhibited Electric Eel Acetylcholinesterase - Viragh_1999_Biochemistry_38_9557
Author(s) : Viragh C , Kovach IM , Pannell L
Ref : Biochemistry , 38 :9557 , 1999
Abstract :
PubMedSearch : Viragh_1999_Biochemistry_38_9557
PubMedID: 10423232

Title : The Push-Pull Mechanism of Dealkylation in Soman-Inhibited Cholinesterases and Their Mutants -
Author(s) : Kovach IM
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :339 , 1998
PubMedID:

Title : Alternate Pathways for Acetic Acid and Acetate Ion Release from Acetylcholinesterase -
Author(s) : Enyedy IJ , Kovach IM
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :368 , 1998
PubMedID:

Title : The pH Dependence of Dealkylation in Soman-Inhibited Cholinesterases and Their Mutants: Further Evidence for a Push-Pull Mechanism - Saxena_1998_Biochemistry_37_15086
Author(s) : Saxena A , Viragh C , Frazier DS , Kovach IM , Maxwell DM , Lockridge O , Doctor BP
Ref : Biochemistry , 37 :15086 , 1998
Abstract :
PubMedSearch : Saxena_1998_Biochemistry_37_15086
PubMedID: 9790671

Title : pH Dependence of Dealkylation in Soman-Inhibited Cholinesterases and Their Mutants -
Author(s) : Viragh C , Saxena A , Frazier DS , Kovach IM , Lockridge O , Doctor BP
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :247 , 1998
PubMedID:

Title : Unique push-pull mechanism of dealkylation in soman-inhibited cholinesterases - Viragh_1997_Biochemistry_36_8243
Author(s) : Viragh C , Akhmetshin R , Kovach IM , Broomfield CA
Ref : Biochemistry , 36 :8243 , 1997
Abstract :
PubMedSearch : Viragh_1997_Biochemistry_36_8243
PubMedID: 9204869

Title : A self-consistent mechanism for dealkylation in soman-inhibited acetylcholinesterase [letter] -
Author(s) : Kovach IM , Akhmetshin R , Enyedy IJ , Viragh C
Ref : Biochemical Journal , 324 :995 , 1997
PubMedID: 9235880

Title : Origins and diversity of the aging reaction in phosphonate adducts of serine hydrolase enzymes: what characteristics of the active site do they probe? - Bencsura_1995_Biochemistry_34_8989
Author(s) : Bencsura A , Enyedy IJ , Kovach IM
Ref : Biochemistry , 34 :8989 , 1995
Abstract :
PubMedSearch : Bencsura_1995_Biochemistry_34_8989
PubMedID: 7619798

Title : Phosphonate Ester Active Site Probes of Acetylcholinesterase, Trypsin and Chymotrypsin -
Author(s) : Bencsura A , Enyedy IJ , Viragh C , Akhmetshin R , Kovach IM
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :155 , 1995
PubMedID:

Title : Identification of amino acid residues involved in the binding of Huperzine A to cholinesterases - Saxena_1994_Protein.Sci_3_1770
Author(s) : Saxena A , Qian N , Kovach IM , Kozikowski AP , Pang YP , Vellom DC , Radic Z , Quinn DM , Taylor P , Doctor BP
Ref : Protein Science , 3 :1770 , 1994
Abstract :
PubMedSearch : Saxena_1994_Protein.Sci_3_1770
PubMedID: 7849595

Title : Efficient product clearance through exit channels in substrate hydrolysis by acetylcholinesterase - Kovach_1994_FEBS.Lett_349_60
Author(s) : Kovach IM , Qian N , Bencsura A
Ref : FEBS Letters , 349 :60 , 1994
Abstract :
PubMedSearch : Kovach_1994_FEBS.Lett_349_60
PubMedID: 8045303

Title : Key active site residues in the inhibition of acetylcholinesterases by soman - Qian_1993_FEBS.Lett_336_263
Author(s) : Qian N , Kovach IM
Ref : FEBS Letters , 336 :263 , 1993
Abstract :
PubMedSearch : Qian_1993_FEBS.Lett_336_263
PubMedID: 8262242

Title : Structure and dynamics of serine hydrolase-organophosphate adducts - Kovach_1988_J.Enzyme.Inhib_2_199
Author(s) : Kovach IM
Ref : J Enzyme Inhib , 2 :199 , 1988
Abstract :
PubMedSearch : Kovach_1988_J.Enzyme.Inhib_2_199
PubMedID: 3241181