Title : First demonstration of a functional role for central nervous system betaine\/{gamma}-aminobutyric acid transporter (mGAT2) based on synergistic anticonvulsant action among inhibitors of mGAT1 and mGAT2 - White_2005_J.Pharmacol.Exp.Ther_312_866 |
Author(s) : White HS , Watson WP , Hansen SL , Slough S , Perregaard J , Sarup A , Bolvig T , Petersen G , Larsson OM , Clausen RP , Frolund B , Falch E , Krogsgaard-Larsen P , Schousboe A |
Ref : Journal of Pharmacology & Experimental Therapeutics , 312 :866 , 2005 |
Abstract : |
PubMedSearch : White_2005_J.Pharmacol.Exp.Ther_312_866 |
PubMedID: 15550575 |
Title : Neuronal nicotinic acetylcholine receptors: structural revelations, target identifications, and therapeutic inspirations - |
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Ref : Journal of Medicinal Chemistry , 48 :4705 , 2005 |
PubMedID: 16033252 |
Title : Carbamoylcholine homologs: synthesis and pharmacology at nicotinic acetylcholine receptors - Jensen_2004_Eur.J.Pharmacol_497_125 |
Author(s) : Jensen AA , Mikkelsen I , Frolund B , Frydenvang K , Brehm L , Jaroszewski JW , Brauner-Osborne H , Falch E , Krogsgaard-Larsen P |
Ref : European Journal of Pharmacology , 497 :125 , 2004 |
Abstract : |
PubMedSearch : Jensen_2004_Eur.J.Pharmacol_497_125 |
PubMedID: 15306197 |
Title : Modification of the philanthotoxin-343 polyamine moiety results in different structure-activity profiles at muscle nicotinic ACh, NMDA and AMPA receptors - Mellor_2003_Neuropharmacol_44_70 |
Author(s) : Mellor IR , Brier TJ , Pluteanu F , Stromgaard K , Saghyan A , Eldursi N , Brierley MJ , Andersen K , Jaroszewski JW , Krogsgaard-Larsen P , Usherwood PN |
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Abstract : |
PubMedSearch : Mellor_2003_Neuropharmacol_44_70 |
PubMedID: 12559123 |
Title : Carbamoylcholine homologs: novel and potent agonists at neuronal nicotinic acetylcholine receptors - Jensen_2003_Mol.Pharmacol_64_865 |
Author(s) : Jensen AA , Mikkelsen I , Frolund B , Brauner-Osborne H , Falch E , Krogsgaard-Larsen P |
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Abstract : |
PubMedSearch : Jensen_2003_Mol.Pharmacol_64_865 |
PubMedID: 14500743 |
Title : Solid-phase synthesis and pharmacological evaluation of analogues of PhTX-12-A potent and selective nicotinic acetylcholine receptor antagonist - Stromgaard_2002_Bioorg.Med.Chem.Lett_12_1159 |
Author(s) : Stromgaard K , Mellor IR , Andersen K , Neagoe I , Pluteanu F , Usherwood PN , Krogsgaard-Larsen P , Jaroszewski JW |
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Abstract : |
PubMedSearch : Stromgaard_2002_Bioorg.Med.Chem.Lett_12_1159 |
PubMedID: 11934578 |
Title : Solid-phase synthesis and biological evaluation of a combinatorial library of philanthotoxin analogues - Stromgaard_2000_J.Med.Chem_43_4526 |
Author(s) : Stromgaard K , Brier TJ , Andersen K , Mellor IR , Saghyan A , Tikhonov D , Usherwood PN , Krogsgaard-Larsen P , Jaroszewski JW |
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Abstract : |
PubMedSearch : Stromgaard_2000_J.Med.Chem_43_4526 |
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Title : Design, synthesis, and biological evaluation of symmetrically and unsymmetrically substituted methoctramine-related polyamines as muscular nicotinic receptor noncompetitive antagonists - Rosini_1999_J.Med.Chem_42_5212 |
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Abstract : |
PubMedSearch : Rosini_1999_J.Med.Chem_42_5212 |
PubMedID: 10602706 |
Title : Synthesis and muscarinic receptor pharmacology of a series of 4,5,6,7-tetrahydroisothiazolo[4,5-c]pyridine bioisosteres of arecoline - Pedersen_1999_Bioorg.Med.Chem_7_795 |
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Abstract : |
PubMedSearch : Pedersen_1999_Bioorg.Med.Chem_7_795 |
PubMedID: 10400332 |
Title : Synthesis and pharmacology of the baclofen homologues 5-amino-4-(4-chlorophenyl)pentanoic acid and the R- and S-enantiomers of 5-amino-3-(4-chlorophenyl)pentanoic acid - Karla_1999_J.Med.Chem_42_2053 |
Author(s) : Karla R , Ebert B , Thorkildsen C , Herdeis C , Johansen TN , Nielsen B , Krogsgaard-Larsen P |
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Abstract : |
PubMedSearch : Karla_1999_J.Med.Chem_42_2053 |
PubMedID: 10354414 |
Title : Analogues of neuroactive polyamine wasp toxins that lack inner basic sites exhibit enhanced antagonism toward a muscle-type mammalian nicotinic acetylcholine receptor - Stromgaard_1999_J.Med.Chem_42_5224 |
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Abstract : |
PubMedSearch : Stromgaard_1999_J.Med.Chem_42_5224 |
PubMedID: 10602707 |
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PubMedSearch : Brauner-Osborne_1996_Eur.J.Pharmacol_313_145 |
PubMedID: 8905341 |
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Abstract : |
PubMedSearch : Sokilde_1996_Arch.Pharm.(Weinheim)_329_95 |
PubMedID: 8851473 |
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PubMedID: |
Title : Annulated heterocyclic bioisosteres of norarecoline. Synthesis and molecular pharmacology at five recombinant human muscarinic acetylcholine receptors - Brauner-Osborne_1995_J.Med.Chem_38_2188 |
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Abstract : |
PubMedSearch : Brauner-Osborne_1995_J.Med.Chem_38_2188 |
PubMedID: 7783150 |
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PubMedSearch : Lagersted_1993_Drug.Des.Discov_9_237 |
PubMedID: 8400005 |
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PubMedID: |
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Abstract : |
PubMedSearch : Sauerberg_1988_J.Med.Chem_31_1312 |
PubMedID: 3385727 |
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PubMedID: 3074541 |
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Abstract : |
PubMedSearch : Falch_1987_Drug.Des.Deliv_2_9 |
PubMedID: 3509345 |
Title : (R)-nipecotic acid ethyl ester: a direct-acting cholinergic agonist that displays greater efficacy at M2 than at M1 muscarinic receptors - Zorn_1987_J.Pharmacol.Exp.Ther_242_173 |
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Abstract : |
PubMedSearch : Zorn_1987_J.Pharmacol.Exp.Ther_242_173 |
PubMedID: 2886636 |
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Abstract : |
PubMedSearch : Sauerberg_1986_Eur.J.Pharmacol_130_125 |
PubMedID: 3780854 |
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Abstract : |
PubMedSearch : Sauerberg_1986_J.Med.Chem_29_1004 |
PubMedID: 3712371 |
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