Krogsgaard-Larsen P

References (24)

Title : Neuronal nicotinic acetylcholine receptors: structural revelations, target identifications, and therapeutic inspirations -
Author(s) : Jensen AA , Frolund B , Liljefors T , Krogsgaard-Larsen P
Ref : Journal of Medicinal Chemistry , 48 :4705 , 2005
PubMedID: 16033252

Title : First demonstration of a functional role for central nervous system betaine\/{gamma}-aminobutyric acid transporter (mGAT2) based on synergistic anticonvulsant action among inhibitors of mGAT1 and mGAT2 - White_2005_J.Pharmacol.Exp.Ther_312_866
Author(s) : White HS , Watson WP , Hansen SL , Slough S , Perregaard J , Sarup A , Bolvig T , Petersen G , Larsson OM , Clausen RP , Frolund B , Falch E , Krogsgaard-Larsen P , Schousboe A
Ref : Journal of Pharmacology & Experimental Therapeutics , 312 :866 , 2005
Abstract :
PubMedSearch : White_2005_J.Pharmacol.Exp.Ther_312_866
PubMedID: 15550575

Title : Carbamoylcholine homologs: synthesis and pharmacology at nicotinic acetylcholine receptors - Jensen_2004_Eur.J.Pharmacol_497_125
Author(s) : Jensen AA , Mikkelsen I , Frolund B , Frydenvang K , Brehm L , Jaroszewski JW , Brauner-Osborne H , Falch E , Krogsgaard-Larsen P
Ref : European Journal of Pharmacology , 497 :125 , 2004
Abstract :
PubMedSearch : Jensen_2004_Eur.J.Pharmacol_497_125
PubMedID: 15306197

Title : Carbamoylcholine homologs: novel and potent agonists at neuronal nicotinic acetylcholine receptors - Jensen_2003_Mol.Pharmacol_64_865
Author(s) : Jensen AA , Mikkelsen I , Frolund B , Brauner-Osborne H , Falch E , Krogsgaard-Larsen P
Ref : Molecular Pharmacology , 64 :865 , 2003
Abstract :
PubMedSearch : Jensen_2003_Mol.Pharmacol_64_865
PubMedID: 14500743

Title : Modification of the philanthotoxin-343 polyamine moiety results in different structure-activity profiles at muscle nicotinic ACh, NMDA and AMPA receptors - Mellor_2003_Neuropharmacol_44_70
Author(s) : Mellor IR , Brier TJ , Pluteanu F , Stromgaard K , Saghyan A , Eldursi N , Brierley MJ , Andersen K , Jaroszewski JW , Krogsgaard-Larsen P , Usherwood PN
Ref : Neuropharmacology , 44 :70 , 2003
Abstract :
PubMedSearch : Mellor_2003_Neuropharmacol_44_70
PubMedID: 12559123

Title : Solid-phase synthesis and pharmacological evaluation of analogues of PhTX-12-A potent and selective nicotinic acetylcholine receptor antagonist - Stromgaard_2002_Bioorg.Med.Chem.Lett_12_1159
Author(s) : Stromgaard K , Mellor IR , Andersen K , Neagoe I , Pluteanu F , Usherwood PN , Krogsgaard-Larsen P , Jaroszewski JW
Ref : Bioorganic & Medicinal Chemistry Lett , 12 :1159 , 2002
Abstract :
PubMedSearch : Stromgaard_2002_Bioorg.Med.Chem.Lett_12_1159
PubMedID: 11934578

Title : Solid-phase synthesis and biological evaluation of a combinatorial library of philanthotoxin analogues - Stromgaard_2000_J.Med.Chem_43_4526
Author(s) : Stromgaard K , Brier TJ , Andersen K , Mellor IR , Saghyan A , Tikhonov D , Usherwood PN , Krogsgaard-Larsen P , Jaroszewski JW
Ref : Journal of Medicinal Chemistry , 43 :4526 , 2000
Abstract :
PubMedSearch : Stromgaard_2000_J.Med.Chem_43_4526
PubMedID: 11087577

Title : Synthesis and pharmacology of the baclofen homologues 5-amino-4-(4-chlorophenyl)pentanoic acid and the R- and S-enantiomers of 5-amino-3-(4-chlorophenyl)pentanoic acid - Karla_1999_J.Med.Chem_42_2053
Author(s) : Karla R , Ebert B , Thorkildsen C , Herdeis C , Johansen TN , Nielsen B , Krogsgaard-Larsen P
Ref : Journal of Medicinal Chemistry , 42 :2053 , 1999
Abstract :
PubMedSearch : Karla_1999_J.Med.Chem_42_2053
PubMedID: 10354414

Title : Analogues of neuroactive polyamine wasp toxins that lack inner basic sites exhibit enhanced antagonism toward a muscle-type mammalian nicotinic acetylcholine receptor - Stromgaard_1999_J.Med.Chem_42_5224
Author(s) : Stromgaard K , Brierley MJ , Andersen K , Slok FA , Mellor IR , Usherwood PN , Krogsgaard-Larsen P , Jaroszewski JW
Ref : Journal of Medicinal Chemistry , 42 :5224 , 1999
Abstract :
PubMedSearch : Stromgaard_1999_J.Med.Chem_42_5224
PubMedID: 10602707

Title : Design, synthesis, and biological evaluation of symmetrically and unsymmetrically substituted methoctramine-related polyamines as muscular nicotinic receptor noncompetitive antagonists - Rosini_1999_J.Med.Chem_42_5212
Author(s) : Rosini M , Budriesi R , Bixel MG , Bolognesi ML , Chiarini A , Hucho F , Krogsgaard-Larsen P , Mellor IR , Minarini A , Tumiatti V , Usherwood PN , Melchiorre C
Ref : Journal of Medicinal Chemistry , 42 :5212 , 1999
Abstract :
PubMedSearch : Rosini_1999_J.Med.Chem_42_5212
PubMedID: 10602706

Title : Synthesis and muscarinic receptor pharmacology of a series of 4,5,6,7-tetrahydroisothiazolo[4,5-c]pyridine bioisosteres of arecoline - Pedersen_1999_Bioorg.Med.Chem_7_795
Author(s) : Pedersen H , Brauner-Osborne H , Ball RG , Frydenvang K , Meier E , Bogeso KP , Krogsgaard-Larsen P
Ref : Bioorganic & Medicinal Chemistry , 7 :795 , 1999
Abstract :
PubMedSearch : Pedersen_1999_Bioorg.Med.Chem_7_795
PubMedID: 10400332

Title : Analogues of carbacholine: synthesis and relationship between structure and affinity for muscarinic and nicotinic acetylcholine receptors - Sokilde_1996_Arch.Pharm.(Weinheim)_329_95
Author(s) : Sokilde B , Mikkelsen I , Stensbol TB , Andersen B , Ebdrup S , Krogsgaard-Larsen P , Falch E
Ref : Arch Pharm (Weinheim) , 329 :95 , 1996
Abstract :
PubMedSearch : Sokilde_1996_Arch.Pharm.(Weinheim)_329_95
PubMedID: 8851473

Title : Functional partial agonism at cloned human muscarinic acetylcholine receptors - Brauner-Osborne_1996_Eur.J.Pharmacol_313_145
Author(s) : Brauner-Osborne H , Ebert B , Brann MR , Falch E , Krogsgaard-Larsen P
Ref : European Journal of Pharmacology , 313 :145 , 1996
Abstract :
PubMedSearch : Brauner-Osborne_1996_Eur.J.Pharmacol_313_145
PubMedID: 8905341

Title : Poster: Molecular pharmacology of O-alkyl-thao compounds using the five cloned muscarinic acetylcholine receptors -
Author(s) : Jorgensen HB , Ebert B , Krogsgaard-Larsen P , Brann MR , Falch E
Ref : Life Sciences , 56(11-12) :1007 , 1995
PubMedID:

Title : Annulated heterocyclic bioisosteres of norarecoline. Synthesis and molecular pharmacology at five recombinant human muscarinic acetylcholine receptors - Brauner-Osborne_1995_J.Med.Chem_38_2188
Author(s) : Brauner-Osborne H , Ebert B , Brann MR , Falch E , Krogsgaard-Larsen P
Ref : Journal of Medicinal Chemistry , 38 :2188 , 1995
Abstract :
PubMedSearch : Brauner-Osborne_1995_J.Med.Chem_38_2188
PubMedID: 7783150

Title : Conformational aspects of the muscarinic receptor interactions of bicyclic isoxazole ester bioisosteres of arecoline - Lagersted_1993_Drug.Des.Discov_9_237
Author(s) : Lagersted A , Falch E , Ebert B , Krogsgaard-Larsen P
Ref : Drug Des Discov , 9 :237 , 1993
Abstract :
PubMedSearch : Lagersted_1993_Drug.Des.Discov_9_237
PubMedID: 8400005

Title : Poster: Heterocyclic muscarinic agonists as experimental tools and potentIal therapeutic agents -
Author(s) : Byrholt Hansen A , Falch E , Jorgensen FS , Krogsgaard-Larsen P
Ref : Trends in Pharmacological Sciences , Suppl :112 , 1989
PubMedID:

Title : Heterocyclic muscarinic agonists. Synthesis and biological activity of some bicyclic sulfonium arecoline bioisosteres - Sauerberg_1988_J.Med.Chem_31_1312
Author(s) : Sauerberg P , Falch E , Meier E , Lembol HL , Krogsgaard-Larsen P
Ref : Journal of Medicinal Chemistry , 31 :1312 , 1988
Abstract :
PubMedSearch : Sauerberg_1988_J.Med.Chem_31_1312
PubMedID: 3385727

Title : Bioisosteres of arecoline as novel CNS-active muscarinic agonists -
Author(s) : Krogsgaard-Larsen P , Falch E , Sauerberg P , Freedman SB , Lembol HL , Meier E
Ref : Trends in Pharmacological Sciences , Suppl :69 , 1988
PubMedID: 3074541

Title : GABA uptake inhibitors. Synthesis and effects on audiogenic seizures of ester prodrugs of nipecotic acid, guvacine and cis-4-hydroxynipecotic acid - Falch_1987_Drug.Des.Deliv_2_9
Author(s) : Falch E , Meldrum BS , Krogsgaard-Larsen P
Ref : Drug Des Deliv , 2 :9 , 1987
Abstract :
PubMedSearch : Falch_1987_Drug.Des.Deliv_2_9
PubMedID: 3509345

Title : (R)-nipecotic acid ethyl ester: a direct-acting cholinergic agonist that displays greater efficacy at M2 than at M1 muscarinic receptors - Zorn_1987_J.Pharmacol.Exp.Ther_242_173
Author(s) : Zorn SH , Duman RS , Giachetti A , Micheletti R , Giraldo E , Krogsgaard-Larsen P , Enna SJ
Ref : Journal of Pharmacology & Experimental Therapeutics , 242 :173 , 1987
Abstract :
PubMedSearch : Zorn_1987_J.Pharmacol.Exp.Ther_242_173
PubMedID: 2886636

Title : Pharmacological profile of a novel class of muscarinic acetylcholine receptor agonists - Sauerberg_1986_Eur.J.Pharmacol_130_125
Author(s) : Sauerberg P , Fjalland B , Larsen JJ , Bach-Lauritsen T , Falch E , Krogsgaard-Larsen P
Ref : European Journal of Pharmacology , 130 :125 , 1986
Abstract :
PubMedSearch : Sauerberg_1986_Eur.J.Pharmacol_130_125
PubMedID: 3780854

Title : A novel class of conformationally restricted heterocyclic muscarinic agonists - Sauerberg_1986_J.Med.Chem_29_1004
Author(s) : Sauerberg P , Larsen JJ , Falch E , Krogsgaard-Larsen P
Ref : Journal of Medicinal Chemistry , 29 :1004 , 1986
Abstract :
PubMedSearch : Sauerberg_1986_J.Med.Chem_29_1004
PubMedID: 3712371

Title : Betel nut constituents as inhibitors of gamma-aminobutyric acid uptake -
Author(s) : Johnston GA , Krogsgaard-Larsen P , Stephanson A
Ref : Nature , 258 :627 , 1975
PubMedID: 1207742