Title : Multi-parameter optimization: Development of a morpholin-3-one derivative with an improved kinetic profile for imaging monoacylglycerol lipase in the brain - He_2022_Eur.J.Med.Chem_243_114750 |
Author(s) : He Y , Grether U , Taddio MF , Meier C , Keller C , Edelmann MR , Honer M , Huber S , Wittwer MB , Heer D , Richter H , Collin L , Hug MN , Hilbert M , Postmus AGJ , Stevens AF , van der Stelt M , Kramer SD , Schibli R , Mu L , Gobbi LC |
Ref : Eur Journal of Medicinal Chemistry , 243 :114750 , 2022 |
Abstract : |
PubMedSearch : He_2022_Eur.J.Med.Chem_243_114750 |
PubMedID: 36137365 |
Gene_locus related to this paper: human-MGLL , mouse-MGLL |
Title : Prodrugs of gamma-Alkyl-modified Nucleoside Triphosphates - improved Inhibition of HIV Reverse Transcriptase - Meier_2020_Angew.Chem.Int.Ed.Engl__ |
Author(s) : Meier C , Zhao C , Weber S , Schols D , Balzarini J |
Ref : Angew Chem Int Ed Engl , : , 2020 |
Abstract : |
PubMedSearch : Meier_2020_Angew.Chem.Int.Ed.Engl__ |
PubMedID: 32379948 |
Title : Bis-cycloSal-d4T-monophosphates: drugs that deliver two molecules of bioactive nucleotides - Ducho_2007_J.Med.Chem_50_1335 |
Author(s) : Ducho C , Gorbig U , Jessel S , Gisch N , Balzarini J , Meier C |
Ref : Journal of Medicinal Chemistry , 50 :1335 , 2007 |
Abstract : |
PubMedSearch : Ducho_2007_J.Med.Chem_50_1335 |
PubMedID: 17328534 |
Title : cycloSal-PMEA and cycloAmb-PMEA: potentially new phosphonate prodrugs based on the cycloSal-pronucleotide approach - Meier_2005_J.Med.Chem_48_8079 |
Author(s) : Meier C , Gorbig U , Muller C , Balzarini J |
Ref : Journal of Medicinal Chemistry , 48 :8079 , 2005 |
Abstract : |
PubMedSearch : Meier_2005_J.Med.Chem_48_8079 |
PubMedID: 16335932 |
Title : Novel cyclosal nucleotides with reduced inhibitory potency toward human butyrylcholinesterase - Ducho_2005_Nucleosides.Nucleotides.Nucleic.Acids_24_519 |
Author(s) : Ducho C , Jessel S , Gisch N , Balzarini J , Meier C |
Ref : Nucleosides Nucleotides Nucleic Acids , 24 :519 , 2005 |
Abstract : |
PubMedSearch : Ducho_2005_Nucleosides.Nucleotides.Nucleic.Acids_24_519 |
PubMedID: 16247982 |
Title : Interaction of cycloSal-pronucleotides with cholinesterases from different origins. A structure-activity relationship - Meier_2004_J.Med.Chem_47_2839 |
Author(s) : Meier C , Ducho C , Gorbig U , Esnouf R , Balzarini J |
Ref : Journal of Medicinal Chemistry , 47 :2839 , 2004 |
Abstract : |
PubMedSearch : Meier_2004_J.Med.Chem_47_2839 |
PubMedID: 15139762 |
Title : Non-inhibition of acetylcholinesterase by cycloSal nucleotides - Ducho_2003_Nucleosides.Nucleotides.Nucleic.Acids_22_841 |
Author(s) : Ducho C , Balzarini J , Meier C |
Ref : Nucleosides Nucleotides Nucleic Acids , 22 :841 , 2003 |
Abstract : |
PubMedSearch : Ducho_2003_Nucleosides.Nucleotides.Nucleic.Acids_22_841 |
PubMedID: 14565292 |
Title : Intracellular metabolism of CycloSaligenyl 3'-azido-2', 3'-dideoxythymidine monophosphate, a prodrug of 3'-azido-2', 3'-dideoxythymidine (zidovudine) - Balzarini_1999_Mol.Pharmacol_56_1354 |
Author(s) : Balzarini J , Naesens L , Aquaro S , Knispel T , Perno C , De Clercq E , Meier C |
Ref : Molecular Pharmacology , 56 :1354 , 1999 |
Abstract : |
PubMedSearch : Balzarini_1999_Mol.Pharmacol_56_1354 |
PubMedID: 10570065 |