| Title : Preclinical Evaluation of the Reversible Monoacylglycerol Lipase PET Tracer (R)-[(11) C]YH132: Application in Drug Development and Neurodegenerative Diseases - He_2024_Chembiochem__e202300819 |
| Author(s) : He Y , Delparente A , Jie C , Keller C , Humm R , Heer D , Collin L , Schibli R , Gobbi L , Grether U , Mu L |
| Ref : Chembiochem , :e202300819 , 2024 |
| Abstract : |
| PubMedSearch : He_2024_Chembiochem__e202300819 |
| PubMedID: 38441502 |
| Title : Enhancing Drug Discovery and Development through the Integration of Medicinal Chemistry, Chemical Biology, and Academia-Industry Partnerships: Insights from Roche's Endocannabinoid System Projects - Aebi_2024_Chimia.(Aarau)_78_499 |
| Author(s) : Aebi J , Atz K , Ametamey SM , Benz J , Blaising J , Butini S , Campiani G , Carreira EM , Collin L , De Lago E , Gazzi T , Gertsch J , Gobbi L , Guba W , Fernandez-Ruiz J , Fingerle J , Haider A , He Y , Heitman LH , Honer M , Hunziker D , Kuhn B , Maccarrone M , Marki HP , Martin RE , Mohr P , Mu L , Nazare M , Nippa DF , Oddi S , O'Hara F , Pacher P , Romero J , Rover S , Rufer AC , Schibli R , Schneider G , Stepan AF , Sykes DA , Ullmer C , van der Stelt M , Veprintsev DB , Wittwer MB , Grether U |
| Ref : Chimia (Aarau) , 78 :499 , 2024 |
| Abstract : |
| PubMedSearch : Aebi_2024_Chimia.(Aarau)_78_499 |
| PubMedID: 39221845 |
| Title : Proof-of-concept optimization of a copper-mediated (18)F-radiosynthesis of a novel MAGL PET tracer on a high-throughput microdroplet platform and its macroscale translation - Lu_2023_Lab.Chip__ |
| Author(s) : Lu Y , He Y , Schibli R , Mu L , van Dam RM |
| Ref : Lab Chip , : , 2023 |
| Abstract : |
| PubMedSearch : Lu_2023_Lab.Chip__ |
| PubMedID: 37818614 |
| Title : Multi-parameter optimization: Development of a morpholin-3-one derivative with an improved kinetic profile for imaging monoacylglycerol lipase in the brain - He_2022_Eur.J.Med.Chem_243_114750 |
| Author(s) : He Y , Grether U , Taddio MF , Meier C , Keller C , Edelmann MR , Honer M , Huber S , Wittwer MB , Heer D , Richter H , Collin L , Hug MN , Hilbert M , Postmus AGJ , Stevens AF , van der Stelt M , Kramer SD , Schibli R , Mu L , Gobbi LC |
| Ref : Eur Journal of Medicinal Chemistry , 243 :114750 , 2022 |
| Abstract : |
| PubMedSearch : He_2022_Eur.J.Med.Chem_243_114750 |
| PubMedID: 36137365 |
| Gene_locus related to this paper: human-MGLL , mouse-MGLL |
| Title : Discovery, synthesis and evaluation of novel reversible monoacylglycerol lipase radioligands bearing a morpholine-3-one scaffold - He_2022_Nucl.Med.Biol_108-109_24 |
| Author(s) : He Y , Gobbi LC , Herde AM , Rombach D , Ritter M , Kuhn B , Wittwer MB , Heer D , Hornsperger B , Bell C , O'Hara F , Benz J , Honer M , Keller C , Collin L , Richter H , Schibli R , Grether U , Mu L |
| Ref : Nucl Med Biol , 108-109 :24 , 2022 |
| Abstract : |
| PubMedSearch : He_2022_Nucl.Med.Biol_108-109_24 |
| PubMedID: 35248850 |
| Gene_locus related to this paper: human-MGLL |
| Title : Development of High Brain-Penetrant and Reversible Monoacylglycerol Lipase PET Tracers for Neuroimaging - He_2022_J.Med.Chem_65_2191 |
| Author(s) : He Y , Schild M , Grether U , Benz J , Leibrock L , Heer D , Topp A , Collin L , Kuhn B , Wittwer M , Keller C , Gobbi LC , Schibli R , Mu L |
| Ref : Journal of Medicinal Chemistry , 65 :2191 , 2022 |
| Abstract : |
| PubMedSearch : He_2022_J.Med.Chem_65_2191 |
| PubMedID: 35089028 |
| Gene_locus related to this paper: human-MGLL |
| Title : Development of reversible monoacylglycerol lipase PET tracers with improved brain uptake - He_2021_Nucl.Med.Biol_96-97_S36 |
| Author(s) : He Y , Schild M , Grether U , Humm R , Keller C , Schibli R , Gobbi L , Mu L |
| Ref : Nucl Med Biol , 96-97 :S36 , 2021 |
| Abstract : |
| PubMedSearch : He_2021_Nucl.Med.Biol_96-97_S36 |
| PubMedID: |