Title : Highly Specific Miniaturized Fluorescent Monoacylglycerol Lipase Probes Enable Translational Research - Hentsch_2025_J.Am.Chem.Soc__ |
Author(s) : Hentsch A , Guberman M , Radetzki S , Kaushik S , Huizenga M , He Y , Contzen J , Kuhn B , Benz J , Schippers M , Paul J , Leibrock L , Collin L , Wittwer M , Topp A , O'Hara F , Heer D , Hochstrasser R , Blaising J , von Kries JP , Mu L , van der Stelt M , Mergenthaler P , Lipstein N , Grether U , Nazare M |
Ref : Journal of the American Chemical Society , : , 2025 |
Abstract : |
PubMedSearch : Hentsch_2025_J.Am.Chem.Soc__ |
PubMedID: 40063733 |
Gene_locus related to this paper: human-MGLL |
Title : Preclinical Evaluation of the Reversible Monoacylglycerol Lipase PET Tracer (R)-[(11) C]YH132: Application in Drug Development and Neurodegenerative Diseases - He_2024_Chembiochem__e202300819 |
Author(s) : He Y , Delparente A , Jie C , Keller C , Humm R , Heer D , Collin L , Schibli R , Gobbi L , Grether U , Mu L |
Ref : Chembiochem , :e202300819 , 2024 |
Abstract : |
PubMedSearch : He_2024_Chembiochem__e202300819 |
PubMedID: 38441502 |
Title : Exploration of (R)-[(11)C]YH168 as a PET tracer for imaging monoacylglycerol lipase in the brain: from mice to non-human primates - He_2024_Eur.J.Nucl.Med.Mol.Imaging__ |
Author(s) : He Y , Zheng M , Gu J , Reichert L , Trimborn J , Zhang H , Keller C , Crosby M , Collin L , Heer D , Pavlovic A , Topp A , Wittwer MB , Grether U , Gobbi L , Schibli R , Huang Y , Mu L |
Ref : Eur J Nucl Med Mol Imaging , : , 2024 |
Abstract : |
PubMedSearch : He_2024_Eur.J.Nucl.Med.Mol.Imaging__ |
PubMedID: 39673602 |
Title : Enhancing Drug Discovery and Development through the Integration of Medicinal Chemistry, Chemical Biology, and Academia-Industry Partnerships: Insights from Roche's Endocannabinoid System Projects - Aebi_2024_Chimia.(Aarau)_78_499 |
Author(s) : Aebi J , Atz K , Ametamey SM , Benz J , Blaising J , Butini S , Campiani G , Carreira EM , Collin L , De Lago E , Gazzi T , Gertsch J , Gobbi L , Guba W , Fernandez-Ruiz J , Fingerle J , Haider A , He Y , Heitman LH , Honer M , Hunziker D , Kuhn B , Maccarrone M , Marki HP , Martin RE , Mohr P , Mu L , Nazare M , Nippa DF , Oddi S , O'Hara F , Pacher P , Romero J , Rover S , Rufer AC , Schibli R , Schneider G , Stepan AF , Sykes DA , Ullmer C , van der Stelt M , Veprintsev DB , Wittwer MB , Grether U |
Ref : Chimia (Aarau) , 78 :499 , 2024 |
Abstract : |
PubMedSearch : Aebi_2024_Chimia.(Aarau)_78_499 |
PubMedID: 39221845 |
Title : Identification of (R)-[(18)F]YH134 for Monoacylglycerol Lipase Neuroimaging and Exploration of Its Use for Central Nervous System and Peripheral Drug Development - He_2023_J.Nucl.Med__ |
Author(s) : He Y , Kramer SD , Grether U , Wittwer MB , Collin L , Kuhn B , Topp A , Heer D , O'Hara F , Honer M , Pavlovic A , Richter H , Ritter M , Rombach D , Keller C , Gobbi L , Mu L |
Ref : J Nucl Med , : , 2023 |
Abstract : |
PubMedSearch : He_2023_J.Nucl.Med__ |
PubMedID: 38164615 |
Title : Proof-of-concept optimization of a copper-mediated (18)F-radiosynthesis of a novel MAGL PET tracer on a high-throughput microdroplet platform and its macroscale translation - Lu_2023_Lab.Chip__ |
Author(s) : Lu Y , He Y , Schibli R , Mu L , van Dam RM |
Ref : Lab Chip , : , 2023 |
Abstract : |
PubMedSearch : Lu_2023_Lab.Chip__ |
PubMedID: 37818614 |
Title : Multi-parameter optimization: Development of a morpholin-3-one derivative with an improved kinetic profile for imaging monoacylglycerol lipase in the brain - He_2022_Eur.J.Med.Chem_243_114750 |
Author(s) : He Y , Grether U , Taddio MF , Meier C , Keller C , Edelmann MR , Honer M , Huber S , Wittwer MB , Heer D , Richter H , Collin L , Hug MN , Hilbert M , Postmus AGJ , Stevens AF , van der Stelt M , Kramer SD , Schibli R , Mu L , Gobbi LC |
Ref : Eur Journal of Medicinal Chemistry , 243 :114750 , 2022 |
Abstract : |
PubMedSearch : He_2022_Eur.J.Med.Chem_243_114750 |
PubMedID: 36137365 |
Gene_locus related to this paper: human-MGLL , mouse-MGLL |
Title : Discovery, synthesis and evaluation of novel reversible monoacylglycerol lipase radioligands bearing a morpholine-3-one scaffold - He_2022_Nucl.Med.Biol_108-109_24 |
Author(s) : He Y , Gobbi LC , Herde AM , Rombach D , Ritter M , Kuhn B , Wittwer MB , Heer D , Hornsperger B , Bell C , O'Hara F , Benz J , Honer M , Keller C , Collin L , Richter H , Schibli R , Grether U , Mu L |
Ref : Nucl Med Biol , 108-109 :24 , 2022 |
Abstract : |
PubMedSearch : He_2022_Nucl.Med.Biol_108-109_24 |
PubMedID: 35248850 |
Gene_locus related to this paper: human-MGLL |
Title : Development of High Brain-Penetrant and Reversible Monoacylglycerol Lipase PET Tracers for Neuroimaging - He_2022_J.Med.Chem_65_2191 |
Author(s) : He Y , Schild M , Grether U , Benz J , Leibrock L , Heer D , Topp A , Collin L , Kuhn B , Wittwer M , Keller C , Gobbi LC , Schibli R , Mu L |
Ref : Journal of Medicinal Chemistry , 65 :2191 , 2022 |
Abstract : |
PubMedSearch : He_2022_J.Med.Chem_65_2191 |
PubMedID: 35089028 |
Gene_locus related to this paper: human-MGLL |
Title : Positron Emission Tomography Imaging of the Endocannabinoid System: Opportunities and Challenges in Radiotracer Development - Hou_2021_J.Med.Chem_64_123 |
Author(s) : Hou L , Rong J , Haider A , Ogasawara D , Varlow C , Schafroth MA , Mu L , Gan J , Xu H , Fowler CJ , Zhang MR , Vasdev N , Ametamey S , Cravatt BF , Wang L , Liang SH |
Ref : Journal of Medicinal Chemistry , 64 :123 , 2021 |
Abstract : |
PubMedSearch : Hou_2021_J.Med.Chem_64_123 |
PubMedID: 33379862 |
Title : Development of reversible monoacylglycerol lipase PET tracers with improved brain uptake - He_2021_Nucl.Med.Biol_96-97_S36 |
Author(s) : He Y , Schild M , Grether U , Humm R , Keller C , Schibli R , Gobbi L , Mu L |
Ref : Nucl Med Biol , 96-97 :S36 , 2021 |
Abstract : |
PubMedSearch : He_2021_Nucl.Med.Biol_96-97_S36 |
PubMedID: |
Title : Limb Muscle Reinnervation with the Nerve-Muscle-Endplate Grafting Technique: An Anatomical Feasibility Study - Mu_2021_Neurol.Res.Int_2021_6009342 |
Author(s) : Mu L , Chen J , Li J , Sobotka S , Nyirenda T |
Ref : Neurol Res Int , 2021 :6009342 , 2021 |
Abstract : |
PubMedSearch : Mu_2021_Neurol.Res.Int_2021_6009342 |
PubMedID: 34925918 |
Title : Role of endocannabinoid signaling in a septohabenular pathway in the regulation of anxiety- and depressive-like behavior - Vickstrom_2021_Mol.Psychiatry_26_3178 |
Author(s) : Vickstrom CR , Liu X , Liu S , Hu MM , Mu L , Hu Y , Yu H , Love SL , Hillard CJ , Liu QS |
Ref : Mol Psychiatry , 26 :3178 , 2021 |
Abstract : |
PubMedSearch : Vickstrom_2021_Mol.Psychiatry_26_3178 |
PubMedID: 33093652 |
Title : Effects of acute and chronic exposures of fluoxetine on the Chinese fish, topmouth gudgeon Pseudorasbora parva - Chen_2018_Ecotoxicol.Environ.Saf_160_104 |
Author(s) : Chen H , Zeng X , Mu L , Hou L , Yang B , Zhao J , Schlenk D , Dong W , Xie L , Zhang Q |
Ref : Ecotoxicology & Environmental Safety , 160 :104 , 2018 |
Abstract : |
PubMedSearch : Chen_2018_Ecotoxicol.Environ.Saf_160_104 |
PubMedID: 29793199 |
Title : Accumulation and effects of Cr(VI) in Japanese medaka (Oryzias latipes) during chronic dissolved and dietary exposures - Chen_2016_Aquat.Toxicol_176_208 |
Author(s) : Chen H , Mu L , Cao J , Mu J , Klerks PL , Luo Y , Guo Z , Xie L |
Ref : Aquat Toxicol , 176 :208 , 2016 |
Abstract : |
PubMedSearch : Chen_2016_Aquat.Toxicol_176_208 |
PubMedID: 27162070 |
Title : Direct, Rapid, and Label-Free Detection of Enzyme-Substrate Interactions in Physiological Buffers Using CMOS-Compatible Nanoribbon Sensors - Mu_2014_Nano.Lett_14_5315 |
Author(s) : Mu L , Droujinine IA , Rajan NK , Sawtelle SD , Reed MA |
Ref : Nano Lett , 14 :5315 , 2014 |
Abstract : |
PubMedSearch : Mu_2014_Nano.Lett_14_5315 |
PubMedID: 25164567 |
Title : Locations of the Motor Endplate Band and Motoneurons Innervating the Sternomastoid Muscle in the Rat - Zhang_2011_Anat.Rec.(Hoboken)_294_295 |
Author(s) : Zhang X , Mu L , Su H , Sobotka S |
Ref : Anatomical Record (Hoboken) , 294 :295 , 2011 |
Abstract : |
PubMedSearch : Zhang_2011_Anat.Rec.(Hoboken)_294_295 |
PubMedID: 21184476 |
Title : Human tongue neuroanatomy: Nerve supply and motor endplates - Mu_2010_Clin.Anat_23_777 |
Author(s) : Mu L , Sanders I |
Ref : Clin Anat , 23 :777 , 2010 |
Abstract : |
PubMedSearch : Mu_2010_Clin.Anat_23_777 |
PubMedID: 20607833 |
Title : Neuroanatomy of the equine dorsal cricoarytenoid muscle: surgical implications - Cheetham_2008_Equine.Vet.J_40_70 |
Author(s) : Cheetham J , Radcliffe CR , Ducharme NG , Sanders I , Mu L , Hermanson JW |
Ref : Equine Vet J , 40 :70 , 2008 |
Abstract : |
PubMedSearch : Cheetham_2008_Equine.Vet.J_40_70 |
PubMedID: 18083663 |
Title : Neuromuscular specializations within human pharyngeal constrictor muscles - Mu_2007_Ann.Otol.Rhinol.Laryngol_116_604 |
Author(s) : Mu L , Sanders I |
Ref : Ann Otol Rhinol Laryngol , 116 :604 , 2007 |
Abstract : |
PubMedSearch : Mu_2007_Ann.Otol.Rhinol.Laryngol_116_604 |
PubMedID: 17847729 |
Title : Anatomical localization of motor endplate bands in the human biceps brachii - Amirali_2007_J.Clin.Neuromuscul.Dis_9_306 |
Author(s) : Amirali A , Mu L , Gracies JM , Simpson DM |
Ref : J Clin Neuromuscul Dis , 9 :306 , 2007 |
Abstract : |
PubMedSearch : Amirali_2007_J.Clin.Neuromuscul.Dis_9_306 |
PubMedID: 18090684 |
Title : Intrinsic properties of the adult human mylohyoid muscle: neural organization, fiber-type distribution, and myosin heavy chain expression - Ren_2005_Dysphagia_20_182 |
Author(s) : Ren M , Mu L |
Ref : Dysphagia , 20 :182 , 2005 |
Abstract : |
PubMedSearch : Ren_2005_Dysphagia_20_182 |
PubMedID: 16362507 |
Title : Neuromuscular specializations of the pharyngeal dilator muscles: II. Compartmentalization of the canine genioglossus muscle - Mu_2000_Anat.Rec_260_308 |
Author(s) : Mu L , Sanders I |
Ref : Anatomical Record , 260 :308 , 2000 |
Abstract : |
PubMedSearch : Mu_2000_Anat.Rec_260_308 |
PubMedID: 11066041 |
Title : Neuromuscular organization of the human upper esophageal sphincter - Mu_1998_Ann.Otol.Rhinol.Laryngol_107_370 |
Author(s) : Mu L , Sanders I |
Ref : Ann Otol Rhinol Laryngol , 107 :370 , 1998 |
Abstract : |
PubMedSearch : Mu_1998_Ann.Otol.Rhinol.Laryngol_107_370 |
PubMedID: 9596213 |
Title : Neuromuscular specializations of the pharyngeal dilator muscles: I. Compartments of the canine geniohyoid muscle - Mu_1998_Anat.Rec_250_146 |
Author(s) : Mu L , Sanders I |
Ref : Anatomical Record , 250 :146 , 1998 |
Abstract : |
PubMedSearch : Mu_1998_Anat.Rec_250_146 |
PubMedID: 9489774 |
Title : The human communicating nerve. An extension of the external superior laryngeal nerve that innervates the vocal cord - Wu_1994_Arch.OtolaryngolHead.Neck.Surg_120_1321 |
Author(s) : Wu BL , Sanders I , Mu L , Biller HF |
Ref : Archives of Otolaryngology Head & Neck Surgery , 120 :1321 , 1994 |
Abstract : |
PubMedSearch : Wu_1994_Arch.OtolaryngolHead.Neck.Surg_120_1321 |
PubMedID: 7980895 |