Title : Identification and initial structure-activity relationships of (R)-5-(2-azetidinylmethoxy)-2-chloropyridine (ABT-594), a potent, orally active, non-opiate analgesic agent acting via neuronal nicotinic acetylcholine receptors - Holladay_1998_J.Med.Chem_41_407 |
Author(s) : Holladay MW , Wasicak JT , Lin NH , He Y , Ryther KB , Bannon AW , Buckley MJ , Kim DJ , Decker MW , Anderson DJ , Campbell JE , Kuntzweiler TA , Donnelly-Roberts D , Piattoni-Kaplan M , Briggs CA , Williams M , Arneric SP |
Ref : Journal of Medicinal Chemistry , 41 :407 , 1998 |
Abstract : Holladay_1998_J.Med.Chem_41_407 |
ESTHER : Holladay_1998_J.Med.Chem_41_407 |
PubMedSearch : Holladay_1998_J.Med.Chem_41_407 |
PubMedID: 9484491 |
Title : ABT-594 [(R)-5-(2-azetidinylmethoxy)-2-chloropyridine]: a novel, orally effective analgesic acting via neuronal nicotinic acetylcholine receptors: I. In vitro characterization - Donnelly-Roberts_1998_J.Pharmacol.Exp.Ther_285_777 |
Author(s) : Donnelly-Roberts D , Puttfarcken PS , Kuntzweiler TA , Briggs CA , Anderson DJ , Campbell JE , Piattoni-Kaplan M , McKenna DG , Wasicak JT , Holladay MW , Williams M , Arneric SP |
Ref : Journal of Pharmacology & Experimental Therapeutics , 285 :777 , 1998 |
Abstract : Donnelly-Roberts_1998_J.Pharmacol.Exp.Ther_285_777 |
ESTHER : Donnelly-Roberts_1998_J.Pharmacol.Exp.Ther_285_777 |
PubMedSearch : Donnelly-Roberts_1998_J.Pharmacol.Exp.Ther_285_777 |
PubMedID: 9580626 |
Title : ABT-089 [2-methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine]: I. A potent and selective cholinergic channel modulator with neuroprotective properties - Sullivan_1997_J.Pharmacol.Exp.Ther_283_235 |
Author(s) : Sullivan JP , Donnelly-Roberts D , Briggs CA , Anderson DJ , Gopalakrishnan M , Xue IC , Piattoni-Kaplan M , Molinari E , Campbell JE , McKenna DG , Gunn DE , Lin NH , Ryther KB , He Y , Holladay MW , Wonnacott S , Williams M , Arneric SP |
Ref : Journal of Pharmacology & Experimental Therapeutics , 283 :235 , 1997 |
Abstract : Sullivan_1997_J.Pharmacol.Exp.Ther_283_235 |
ESTHER : Sullivan_1997_J.Pharmacol.Exp.Ther_283_235 |
PubMedSearch : Sullivan_1997_J.Pharmacol.Exp.Ther_283_235 |
PubMedID: 9336329 |
Title : Stable expression, pharmacologic properties and regulation of the human neuronal nicotinic acetylcholine alpha 4 beta 2 receptor - Gopalakrishnan_1996_J.Pharmacol.Exp.Ther_276_289 |
Author(s) : Gopalakrishnan M , Monteggia LM , Anderson DJ , Molinari EJ , Piattoni-Kaplan M , Donnelly-Roberts D , Arneric SP , Sullivan JP |
Ref : Journal of Pharmacology & Experimental Therapeutics , 276 :289 , 1996 |
Abstract : Gopalakrishnan_1996_J.Pharmacol.Exp.Ther_276_289 |
ESTHER : Gopalakrishnan_1996_J.Pharmacol.Exp.Ther_276_289 |
PubMedSearch : Gopalakrishnan_1996_J.Pharmacol.Exp.Ther_276_289 |
PubMedID: 8558445 |
Title : A-85380 [3-(2(S)-azetidinylmethoxy) pyridine]: in vitro pharmacological properties of a novel, high affinity alpha 4 beta 2 nicotinic acetylcholine receptor ligand - Sullivan_1996_Neuropharmacol_35_725 |
Author(s) : Sullivan JP , Donnelly-Roberts D , Briggs CA , Anderson DJ , Gopalakrishnan M , Piattoni-Kaplan M , Campbell JE , McKenna DG , Molinari E , Hettinger AM , Garvey DS , Wasicak JT , Holladay MW , Williams M , Arneric SP |
Ref : Neuropharmacology , 35 :725 , 1996 |
Abstract : Sullivan_1996_Neuropharmacol_35_725 |
ESTHER : Sullivan_1996_Neuropharmacol_35_725 |
PubMedSearch : Sullivan_1996_Neuropharmacol_35_725 |
PubMedID: 8887981 |
Title : Erysodine, a competitive antagonist at neuronal nicotinic acetylcholine receptors - Decker_1995_Eur.J.Pharmacol_280_79 |
Author(s) : Decker MW , Anderson DJ , Brioni JD , Donnelly-Roberts D , Kang CH , O'Neill AB , Piattoni-Kaplan M , Swanson S , Sullivan JP |
Ref : European Journal of Pharmacology , 280 :79 , 1995 |
Abstract : Decker_1995_Eur.J.Pharmacol_280_79 |
ESTHER : Decker_1995_Eur.J.Pharmacol_280_79 |
PubMedSearch : Decker_1995_Eur.J.Pharmacol_280_79 |
PubMedID: 7498257 |
Title : (+\/-)-Epibatidine elicits a diversity of in vitro and in vivo effects mediated by nicotinic acetylcholine receptors - Sullivan_1994_J.Pharmacol.Exp.Ther_271_624 |
Author(s) : Sullivan JP , Decker MW , Brioni JD , Donnelly-Roberts D , Anderson DJ , Bannon AW , Kang CH , Adams P , Piattoni-Kaplan M , Buckley MJ |
Ref : Journal of Pharmacology & Experimental Therapeutics , 271 :624 , 1994 |
Abstract : Sullivan_1994_J.Pharmacol.Exp.Ther_271_624 |
ESTHER : Sullivan_1994_J.Pharmacol.Exp.Ther_271_624 |
PubMedSearch : Sullivan_1994_J.Pharmacol.Exp.Ther_271_624 |
PubMedID: 7965777 |