| Title : Syntheses and structure-activity relationship (SAR) studies of 2,5-diazabicyclo[2.2.1]heptanes as novel alpha7 neuronal nicotinic receptor (NNR) ligands - Li_2010_Bioorg.Med.Chem.Lett_20_3636 |
| Author(s) : Li T , Bunnelle WH , Ryther KB , Anderson DJ , Malysz J , Helfrich R , Gronlien JH , Hakerud M , Peters D , Schrimpf MR , Gopalakrishnan M , Ji J |
| Ref : Bioorganic & Medicinal Chemistry Lett , 20 :3636 , 2010 |
| Abstract : Li_2010_Bioorg.Med.Chem.Lett_20_3636 |
| ESTHER : Li_2010_Bioorg.Med.Chem.Lett_20_3636 |
| PubMedSearch : Li_2010_Bioorg.Med.Chem.Lett_20_3636 |
| PubMedID: 20472430 |
| Title : Structure-activity studies related to ABT-594, a potent nonopioid analgesic agent: effect of pyridine and azetidine ring substitutions on nicotinic acetylcholine receptor binding affinity and analgesic activity in mice - Holladay_1998_Bioorg.Med.Chem.Lett_8_2797 |
| Author(s) : Holladay MW , Bai H , Li Y , Lin NH , Daanen JF , Ryther KB , Wasicak JT , Kincaid JF , He Y , Hettinger AM , Huang P , Anderson DJ , Bannon AW , Buckley MJ , Campbell JE , Donnelly-Roberts D , Gunther KL , Kim DJ , Kuntzweiler TA , Sullivan JP , Decker MW , Arneric SP |
| Ref : Bioorganic & Medicinal Chemistry Lett , 8 :2797 , 1998 |
| Abstract : Holladay_1998_Bioorg.Med.Chem.Lett_8_2797 |
| ESTHER : Holladay_1998_Bioorg.Med.Chem.Lett_8_2797 |
| PubMedSearch : Holladay_1998_Bioorg.Med.Chem.Lett_8_2797 |
| PubMedID: 9873625 |
| Title : Identification and initial structure-activity relationships of (R)-5-(2-azetidinylmethoxy)-2-chloropyridine (ABT-594), a potent, orally active, non-opiate analgesic agent acting via neuronal nicotinic acetylcholine receptors - Holladay_1998_J.Med.Chem_41_407 |
| Author(s) : Holladay MW , Wasicak JT , Lin NH , He Y , Ryther KB , Bannon AW , Buckley MJ , Kim DJ , Decker MW , Anderson DJ , Campbell JE , Kuntzweiler TA , Donnelly-Roberts D , Piattoni-Kaplan M , Briggs CA , Williams M , Arneric SP |
| Ref : Journal of Medicinal Chemistry , 41 :407 , 1998 |
| Abstract : Holladay_1998_J.Med.Chem_41_407 |
| ESTHER : Holladay_1998_J.Med.Chem_41_407 |
| PubMedSearch : Holladay_1998_J.Med.Chem_41_407 |
| PubMedID: 9484491 |
| Title : Synthesis and structure-activity relationships of pyridine-modified analogs of 3-[2-((S)-pyrrolidinyl)methoxy]pyridine, A-84543, a potent nicotinic acetylcholine receptor agonist - Lin_1998_Bioorg.Med.Chem.Lett_8_249 |
| Author(s) : Lin NH , Gunn DE , Li Y , He Y , Bai H , Ryther KB , Kuntzweiler T , Donnelly-Roberts D , Anderson DJ , Campbell JE , Sullivan JP , Arneric SP , Holladay MW |
| Ref : Bioorganic & Medicinal Chemistry Lett , 8 :249 , 1998 |
| Abstract : Lin_1998_Bioorg.Med.Chem.Lett_8_249 |
| ESTHER : Lin_1998_Bioorg.Med.Chem.Lett_8_249 |
| PubMedSearch : Lin_1998_Bioorg.Med.Chem.Lett_8_249 |
| PubMedID: 9871663 |
| Title : Antinociceptive effects of the novel neuronal nicotinic acetylcholine receptor agonist, ABT-594, in mice - Decker_1998_Eur.J.Pharmacol_346_23 |
| Author(s) : Decker MW , Bannon AW , Buckley MJ , Kim DJ , Holladay MW , Ryther KB , Lin NH , Wasicak JT , Williams M , Arneric SP |
| Ref : European Journal of Pharmacology , 346 :23 , 1998 |
| Abstract : Decker_1998_Eur.J.Pharmacol_346_23 |
| ESTHER : Decker_1998_Eur.J.Pharmacol_346_23 |
| PubMedSearch : Decker_1998_Eur.J.Pharmacol_346_23 |
| PubMedID: 9617748 |
| Title : ABT-089 [2-methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine]: I. A potent and selective cholinergic channel modulator with neuroprotective properties - Sullivan_1997_J.Pharmacol.Exp.Ther_283_235 |
| Author(s) : Sullivan JP , Donnelly-Roberts D , Briggs CA , Anderson DJ , Gopalakrishnan M , Xue IC , Piattoni-Kaplan M , Molinari E , Campbell JE , McKenna DG , Gunn DE , Lin NH , Ryther KB , He Y , Holladay MW , Wonnacott S , Williams M , Arneric SP |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 283 :235 , 1997 |
| Abstract : Sullivan_1997_J.Pharmacol.Exp.Ther_283_235 |
| ESTHER : Sullivan_1997_J.Pharmacol.Exp.Ther_283_235 |
| PubMedSearch : Sullivan_1997_J.Pharmacol.Exp.Ther_283_235 |
| PubMedID: 9336329 |
| Title : Functional characterization of the novel neuronal nicotinic acetylcholine receptor ligand GTS-21 in vitro and in vivo - Briggs_1997_Pharmacol.Biochem.Behav_57_231 |
| Author(s) : Briggs CA , Anderson DJ , Brioni JD , Buccafusco JJ , Buckley MJ , Campbell JE , Decker MW , Donnelly-Roberts D , Elliott RL , Gopalakrishnan M , Holladay MW , Hui YH , Jackson WJ , Kim DJ , Marsh KC , O'Neill A , Prendergast MA , Ryther KB , Sullivan JP , Arneric SP |
| Ref : Pharmacol Biochem Behav , 57 :231 , 1997 |
| Abstract : Briggs_1997_Pharmacol.Biochem.Behav_57_231 |
| ESTHER : Briggs_1997_Pharmacol.Biochem.Behav_57_231 |
| PubMedSearch : Briggs_1997_Pharmacol.Biochem.Behav_57_231 |
| PubMedID: 9164577 |
| Title : Structure-activity studies on 2-methyl-3-(2(S)-pyrrolidinylmethoxy) pyridine (ABT-089): an orally bioavailable 3-pyridyl ether nicotinic acetylcholine receptor ligand with cognition-enhancing properties - Lin_1997_J.Med.Chem_40_385 |
| Author(s) : Lin NH , Gunn DE , Ryther KB , Garvey DS , Donnelly-Roberts D , Decker MW , Brioni JD , Buckley MJ , Rodrigues AD , Marsh KG , Anderson DJ , Buccafusco JJ , Prendergast MA , Sullivan JP , Williams M , Arneric SP , Holladay MW |
| Ref : Journal of Medicinal Chemistry , 40 :385 , 1997 |
| Abstract : Lin_1997_J.Med.Chem_40_385 |
| ESTHER : Lin_1997_J.Med.Chem_40_385 |
| PubMedSearch : Lin_1997_J.Med.Chem_40_385 |
| PubMedID: 9022806 |