| Title : Design, synthesis, biological evaluation, and X-ray single crystal structure of novel computer-aided-drug-designbased alpha-mangostin derivatives: Multifunctional ligands against Alzheimer's disease - Chen_2025_Arch.Pharm.(Weinheim)_358_e2400671 |
| Author(s) : Chen Q , Li X , Xiao W , Sun Y , Shen R , Kou X , Yang A |
| Ref : Arch Pharm (Weinheim) , 358 :e2400671 , 2025 |
| Abstract : |
| PubMedSearch : Chen_2025_Arch.Pharm.(Weinheim)_358_e2400671 |
| PubMedID: 40059628 |
| Title : Study of multifunctional anti-AD ligands: design, synthesis, X-ray crystal structure and biological evaluation of diosmetin derivatives - Yang_2024_Mol.Divers__ |
| Author(s) : Yang A , Yi X , Zhang H , Chen Q , Shen R , Kou X |
| Ref : Mol Divers , : , 2024 |
| Abstract : |
| PubMedSearch : Yang_2024_Mol.Divers__ |
| PubMedID: 38935304 |
| Title : Diosmetin derivatives as multifunctional anti-AD ligands: Design, synthesis, and biological evaluation - Yang_2024_Chem.Biol.Drug.Des_103_e14529 |
| Author(s) : Yang A , Yi X , Zhang H , Shen R , Kou X |
| Ref : Chemical Biology Drug Des , 103 :e14529 , 2024 |
| Abstract : |
| PubMedSearch : Yang_2024_Chem.Biol.Drug.Des_103_e14529 |
| PubMedID: 38670598 |
| Title : Soluble epoxide hydrolase deficiency attenuates airway inflammation in COPD via IRE1alpha\/JNK\/AP-1 signaling pathway - Yu_2023_J.Inflamm.(Lond)_20_36 |
| Author(s) : Yu Y , Yang A , He X , Wu B , Wu Y , Li Y , Nie S , Xu B , Wang H , Yu G |
| Ref : J Inflamm (Lond) , 20 :36 , 2023 |
| Abstract : |
| PubMedSearch : Yu_2023_J.Inflamm.(Lond)_20_36 |
| PubMedID: 37915073 |
| Title : N-Amidation of Nitrogen-Containing Heterocyclic Compounds: Can We Apply Enzymatic Tools? - Yang_2023_Bioengineering.(Basel)_10_ |
| Author(s) : Yang A , Miao X , Yang L , Xu C , Liu W , Xian M , Zou H |
| Ref : Bioengineering (Basel) , 10 : , 2023 |
| Abstract : |
| PubMedSearch : Yang_2023_Bioengineering.(Basel)_10_ |
| PubMedID: 36829716 |
| Title : Emodin derivatives as promising multi-aspect intervention agents for amyloid aggregation: molecular docking\/dynamics simulation, bioactivities evaluation, and cytoprotection - Shen_2023_Mol.Divers__2 |
| Author(s) : Shen R , Zhao W , Li X , Liu J , Yang A , Kou X |
| Ref : Mol Divers , : , 2023 |
| Abstract : |
| PubMedSearch : Shen_2023_Mol.Divers__2 |
| PubMedID: 37737959 |
| Title : Design, Synthesis, Calculation and Biological Activity Studies Based on Privileged Coumarin Derivatives as Multifunctional Anti-AD Lead Compound - Wang_2022_Chem.Biodivers__ |
| Author(s) : Wang H , Su M , Shi X , Li X , Zhang X , Yang A , Shen R |
| Ref : Chem Biodivers , : , 2022 |
| Abstract : |
| PubMedSearch : Wang_2022_Chem.Biodivers__ |
| PubMedID: 36461922 |
| Title : A multifunctional anti-AD approach: Design, synthesis, X-ray crystal structure, biological evaluation and molecular docking of chrysin derivatives - Yang_2022_Eur.J.Med.Chem_233_114216 |
| Author(s) : Yang A , Liu C , Zhang H , Wu J , Shen R , Kou X |
| Ref : Eur Journal of Medicinal Chemistry , 233 :114216 , 2022 |
| Abstract : |
| PubMedSearch : Yang_2022_Eur.J.Med.Chem_233_114216 |
| PubMedID: 35227980 |
| Title : Novel chrysin derivatives as hidden multifunctional agents for anti-Alzheimer's disease: design, synthesis and in vitro evaluation - Liu_2021_Eur.J.Pharm.Sci__105976 |
| Author(s) : Liu C , Kou X , Wang X , Wu J , Yang A , Shen R |
| Ref : Eur J Pharm Sci , :105976 , 2021 |
| Abstract : |
| PubMedSearch : Liu_2021_Eur.J.Pharm.Sci__105976 |
| PubMedID: 34419572 |
| Title : A review on alpha-mangostin as a potential multi-target-directed ligand for Alzheimer's disease - Yang_2021_Eur.J.Pharmacol__173950 |
| Author(s) : Yang A , Liu C , Wu J , Kou X , Shen R |
| Ref : European Journal of Pharmacology , :173950 , 2021 |
| Abstract : |
| PubMedSearch : Yang_2021_Eur.J.Pharmacol__173950 |
| PubMedID: 33607107 |
| Title : Design, synthesis and biological evaluation of naringenin carbamate derivatives as potential multifunctional agents for the treatment of Alzheimer's disease - Wu_2021_Bioorg.Med.Chem.Lett__128316 |
| Author(s) : Wu J , Kou X , Ju H , Zhang H , Yang A , Shen R |
| Ref : Bioorganic & Medicinal Chemistry Lett , :128316 , 2021 |
| Abstract : |
| PubMedSearch : Wu_2021_Bioorg.Med.Chem.Lett__128316 |
| PubMedID: 34391893 |
| Title : Design, synthesis and biological evaluation of xanthone derivatives for possible treatment of Alzheimer's disease based on multi-target strategy - Yang_2020_Chem.Biodivers_17_e2000442 |
| Author(s) : Yang A , Yu Q , Ju H , Song L , Kou X , Shen R |
| Ref : Chem Biodivers , 17 :e2000442 , 2020 |
| Abstract : |
| PubMedSearch : Yang_2020_Chem.Biodivers_17_e2000442 |
| PubMedID: 32692899 |
| Title : Adipocyte lipolysis: from molecular mechanisms of regulation to disease and therapeutics - Yang_2020_Biochem.J_477_985 |
| Author(s) : Yang A , Mottillo EP |
| Ref : Biochemical Journal , 477 :985 , 2020 |
| Abstract : |
| PubMedSearch : Yang_2020_Biochem.J_477_985 |
| PubMedID: 32168372 |
| Title : Design, synthesis and anti-Alzheimer's disease activity study of xanthone derivatives based on multi-target strategy - Kou_2019_Bioorg.Med.Chem.Lett__126927 |
| Author(s) : Kou X , Song L , Wang Y , Yu Q , Ju H , Yang A , Shen R |
| Ref : Bioorganic & Medicinal Chemistry Lett , :126927 , 2019 |
| Abstract : |
| PubMedSearch : Kou_2019_Bioorg.Med.Chem.Lett__126927 |
| PubMedID: 31901382 |
| Title : Neurotransmitter Imbalance in the Brain and Alzheimer's Disease Pathology - Snowden_2019_J.Alzheimers.Dis_72_35 |
| Author(s) : Snowden SG , Ebshiana AA , Hye A , Pletnikova O , O'Brien R , Yang A , Troncoso J , Legido-Quigley C , Thambisetty M |
| Ref : J Alzheimers Dis , 72 :35 , 2019 |
| Abstract : |
| PubMedSearch : Snowden_2019_J.Alzheimers.Dis_72_35 |
| PubMedID: 31561368 |
| Title : Dynamic interactions of ABHD5 with PNPLA3 regulate triacylglycerol metabolism in brown adipocytes - Yang_2019_Nat.Metab_1_560 |
| Author(s) : Yang A , Mottillo EP , Mladenovic-Lucas L , Zhou L , Granneman JG |
| Ref : Nat Metab , 1 :560 , 2019 |
| Abstract : |
| PubMedSearch : Yang_2019_Nat.Metab_1_560 |
| PubMedID: 31497752 |
| Gene_locus related to this paper: human-ABHD5 |
| Title : Encapsulating drugs in biodegradable ultrafine fibers through co-axial electrospinning - Huang_2006_J.Biomed.Mater.Res.A_77_169 |
| Author(s) : Huang ZM , He CL , Yang A , Zhang Y , Han XJ , Yin J , Wu Q |
| Ref : J Biomed Mater Res A , 77 :169 , 2006 |
| Abstract : |
| PubMedSearch : Huang_2006_J.Biomed.Mater.Res.A_77_169 |
| PubMedID: 16392131 |
| Title : The repression of human differentiation-related gene NDRG2 expression by Myc via Miz-1-dependent interaction with the NDRG2 core promoter - Zhang_2006_J.Biol.Chem_281_39159 |
| Author(s) : Zhang J , Li F , Liu X , Shen L , Liu J , Su J , Zhang W , Deng Y , Wang L , Liu N , Han W , Ji S , Yang A , Han H , Yao L |
| Ref : Journal of Biological Chemistry , 281 :39159 , 2006 |
| Abstract : |
| PubMedSearch : Zhang_2006_J.Biol.Chem_281_39159 |
| PubMedID: 17050536 |