Esterase_phb_PHAZ
Relationship
Comment
This is a circularly permuted variant of the alpha/beta hydrolase fold. so could be recognised as a subfamily of Esterase_phb (circular permutation: the first 100 residues are found in c-terminus in Esterase phb)
Database
Interpro : IPR010126 Esterase, PHB depolymerase
PIRSF : No PIRSF
Pdoc : No Pdoc
Pfam : PF10503 Esterase_phd
Prints : No Print
EC Number : No EC Number
Sequences
| Peptide in | Fasta |
| Nucleotide in | Fasta |
| Alignment with Multalin | Text only |
| Seed alignment with MAFFT | No colour / coloured with Mview |
| Alignment with MAFFT | No colour / coloured with Mview |
| Dendrogram | The dnd file |
| Structure | Name | Proteins |
|---|---|---|
| 2D80 | Crystal structure of PHB depolymerase from Penicillium funiculosum | penfu-PHAZ |
| 2D81 | Crystal structure of PHB depolymerase from Penicillium funiculosum (S39A) complexed with R3HB trimer | penfu-PHAZ |
| Gene_locus | Name | Species |
|---|---|---|
| rhoru-q6ynp7 | Rhodospirillum rubrum Poly(3-hydroxyalkanoate) depolymerase phaZ1 | Rhodospirillum rubrum |
| aspfu-q4w9v8 | Neosartorya fumigata (strain ATCC MYA-4609 \/ Af293 \/ CBS 101355 \/ FGSC A1100) (Aspergillus fumigatus) Carboxylic ester hydrolase | Aspergillus fumigatus Af293 |
| 9burk-Q5YEW3 | Schlegelella sp. KB1a PHB depolymerase (phaZ) gene | Schlegelella sp. KB1a |
| acisp-Q9ZNH8 | Acidovorax sp. TP4 phb depolymerase | Acidovorax sp. TP4 |
| calma-PHAZ | Caldimonas manganoxidans phb depolymerase precursor | Caldimonas manganoxidans |
| comac-PHAZCAC | Comamonas acidovorans (Pseudomonas acidovorans) polyhydroxybutyrate depolymerase | Comamonas acidovorans |
| comte-PHAZ | Comamonas testosteroni (Pseudomonas testosteroni), Comamonas sp, poly(3-hydroxybutyrate) depolymerase | Comamonas testosteroni |
| penfu-PHAZ |  Penicillium funiculosum Polyhydroxybutyrate Depolymerase |
Penicillium funiculosum |
| 9euro-a0a421cwa8 | Aspergillus turcosus Polyhydroxybutyrate Depolymerase CBM1 domain-containing protein | Aspergillus turcosus |
| strex-PHAZ | Streptomyces exfoliatus (Streptomyces hydrogenans) poly(3-hydroxybutyrate) depolymerase | Streptomyces exfoliatus |
| Substrate | Chemical Nomenclature | Proteins |
|---|---|---|
| Polybutylene-succinate-co-adipate | aspor-cutas calma-PHAZ burgl-lipas sacvd-c7mve8 psea2-s6bc01 burvg-a4jm54 9burk-i3rta9 | |
| Polybutylene-succinate | aspor-cutas canar-LipB fusso-cutas acide-PBSA paeam-PLAA amymu-a0a0h3des9 aspfu-q4w9v8 sacvd-c7mve8 psea2-s6bc01 crysp-Q874E9 | |
| Polyethylene-succinate | 9zzzz-A0A0G3FEJ8 aspfu-q4w9v8 psecl-LIP1 psecl-LIP2 | |
| RB3 | (3R)-3-[(3R)-3-[(3R)-3-hydroxybutanoyl]oxybutanoyl]oxybutanoic acid | psele-PHAZ7 penfu-PHAZ aspfu-q4w9v8 |
| PHB | poly(3-hydroxybutyrate) | psesp-PHBDP1 aspfu-q4w9v8 crysp-Q874E9 alceu-phbc |
References (2)
| Title : The PHA Depolymerase Engineering Database: A systematic analysis tool for the diverse family of polyhydroxyalkanoate (PHA) depolymerases - Knoll_2009_BMC.Bioinformatics_10_89 |
| Author(s) : Knoll M , Hamm TM , Wagner F , Martinez V , Pleiss J |
| Ref : BMC Bioinformatics , 10 :89 , 2009 |
| Abstract : |
| PubMedSearch : Knoll_2009_BMC.Bioinformatics_10_89 |
| PubMedID: 19296857 |
| Title : The crystal structure of polyhydroxybutyrate depolymerase from Penicillium funiculosum provides insights into the recognition and degradation of biopolyesters - Hisano_2006_J.Mol.Biol_356_993 |
| Author(s) : Hisano T , Kasuya K , Tezuka Y , Ishii N , Kobayashi T , Shiraki M , Oroudjev E , Hansma H , Iwata T , Doi Y , Saito T , Miki K |
| Ref : Journal of Molecular Biology , 356 :993 , 2006 |
| Abstract : |
| PubMedSearch : Hisano_2006_J.Mol.Biol_356_993 |
| PubMedID: 16405909 |
| Gene_locus related to this paper: penfu-PHAZ |