bovin-ABHD16B

Bos taurus (Bovine); Bos mutus (wild yak) Abhydrolase domain containing 16B

Comment

Other strains: Bos taurus (Bovine)\; Bos mutus (wild yak) || Shan et al.<\/A> identified a nonsense mutation in the bovine Abhydrolase domain containing 16B gene ABHD16B (SNP rs468948776 AC_000170 g.54429815G>A) associated with male subfertility in Holstein cattle. The mutation causes a premature stop codon at amino acid position Glu 218, resulting in a truncation of 235 C-terminal amino acids. ABHD16B is involved in lipid biosynthesis in testis and is crucial for fertilization

Relationship

Family : ABHD16

Block : X

Position in NCBI Life Tree : Bos taurus

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Deuterostomia N E > Chordata N E > Craniata N E > Vertebrata N E > Gnathostomata N E > Teleostomi N E > Euteleostomi N E > Sarcopterygii N E > Dipnotetrapodomorpha N E > Tetrapoda N E > Amniota N E > Mammalia N E > Theria N E > Eutheria N E > Boreoeutheria N E > Laurasiatheria N E > Cetartiodactyla N E > Ruminantia N E > Pecora N E > Bovidae N E > Bovinae N E > Bos N E > Bos taurus N E

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

MCVVCFVKAL VHVFKIYLTA NYTYNFRGWP VDFRWDDVRA AAGSGSSHRA LTCAAAAAGV WLLRGAALGE DSPVRLPRAA RSQAQCLLQQ IRELPSQLAS YALAHSLGRW LVYPGSMFLM TRALLPLLQQ GQERLVERYR GRRAKLVACD GNEIDTMFMD RRQDPGSHGR GLRLVICCEG NAGFYEMGCL SAPLEAGYSV LGWNHPGFGG STGAPFPQHD ANAMDVVVKY ALHRLHFPPA HVVVYGWSIG GFTATWATMT YPELGALVLD ATFDDLVPLA LKVMPHSWKG LVVRTVREHF NLNVAEQLCR YPGPVLLLRR TQDDVVSTAG HLRPLPSGVV EGNRGNELLL RLLQHRYPAV MAREGLAIVT RWLRAGSLAQ EAAFYARYRV DDEWCLSLLR SYLTHCEDQQ EDEETWGSHG LAFPWLVGQG LSPRRRRQLA LFLARKHLKN VEATHCSPLE PEDFQLPWRL

References (3)

Title : alpha\/beta-Hydrolase D16B Truncation Results in Premature Sperm Capacitation in Cattle - Shan_2022_Int.J.Mol.Sci_23_
Author(s) : Shan S , Xu F , Hirschfeld M , Herrmann C , Schulze M , Sharifi AR , Hoelker M , Brenig B
Ref : Int J Mol Sci , 23 : , 2022
Abstract :
PubMedSearch : Shan_2022_Int.J.Mol.Sci_23_
PubMedID: 35887122
Gene_locus related to this paper: bovin-ABHD16B , human-ABHD16B

Title : Association of alpha\/beta-Hydrolase D16B with Bovine Conception Rate and Sperm Plasma Membrane Lipid Composition - Shan_2020_Int.J.Mol.Sci_21_
Author(s) : Shan S , Xu F , Bleyer M , Becker S , Melbaum T , Wemheuer W , Hirschfeld M , Wacker C , Zhao S , Schutz E , Brenig B
Ref : Int J Mol Sci , 21 : , 2020
Abstract :
PubMedSearch : Shan_2020_Int.J.Mol.Sci_21_
PubMedID: 31963602
Gene_locus related to this paper: bovin-ABHD16B , human-ABHD16B , mouse-Abhd16b

Title : The yak genome and adaptation to life at high altitude - Qiu_2012_Nat.Genet_44_946
Author(s) : Qiu Q , Zhang G , Ma T , Qian W , Wang J , Ye Z , Cao C , Hu Q , Kim J , Larkin DM , Auvil L , Capitanu B , Ma J , Lewin HA , Qian X , Lang Y , Zhou R , Wang L , Wang K , Xia J , Liao S , Pan S , Lu X , Hou H , Wang Y , Zang X , Yin Y , Ma H , Zhang J , Wang Z , Zhang Y , Zhang D , Yonezawa T , Hasegawa M , Zhong Y , Liu W , Huang Z , Zhang S , Long R , Yang H , Lenstra JA , Cooper DN , Wu Y , Shi P , Liu J
Ref : Nat Genet , 44 :946 , 2012
Abstract :
PubMedSearch : Qiu_2012_Nat.Genet_44_946
PubMedID: 22751099
Gene_locus related to this paper: bosmu-l8ic43 , bovin-2neur , bovin-balip , bovin-BCHE , bovin-e1bbv2 , bovin-e1bn79 , bovin-est8 , bovin-f1mi11 , bovin-f1n385 , bovin-g3mxp5 , bovin-lipli , bovin-lipr2 , bovin-q2kj30 , bovin-q3sz79 , bovin-q3t0r6 , bovin-ABHDA , bovin-q08dw9 , bovin-ABHD16B , bovin-SPG21 , bovin-srac1 , bovin-TEX30 , 9ceta-l8iwv2 , 9ceta-l8idy3 , 9ceta-l8hsi3 , bovin-e1bjq9 , bovin-f1mc21 , 9ceta-l8hyl8 , bovin-LIPG , bovin-a0a3q1nm09 , bovin-f1n2i5 , bovin-a0aaa9t509