Homo sapiens (Human) NDRG4, N-myc downstream-regulated gene 4 protein (smap-8) flj42011 flj16174 flj44611
Brain development-related molecule 1, N-myc downstream-regulated gene 4 protein, Vascular smooth muscle cell-associated protein 8, SMAP-8 old human-ndr4. A loss-of-function mutation p.T256M in NDRG4 is implicated in the pathogenesis of pulmonary atresia with ventricular septal defect (PA\/VSD) and tetralogy of Fallot (TOF)
Family : Ndr_family
Block : X
Position in NCBI Life Tree : Homo sapiens
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Deuterostomia N E > Chordata N E > Craniata N E > Vertebrata N E > Gnathostomata N E > Teleostomi N E > Euteleostomi N E > Sarcopterygii N E > Dipnotetrapodomorpha N E > Tetrapoda N E > Amniota N E > Mammalia N E > Theria N E > Eutheria N E > Boreoeutheria N E > Euarchontoglires N E > Primates N E > Haplorrhini N E > Simiiformes N E > Catarrhini N E > Hominoidea N E > Hominidae N E > Homininae N E > Homo N E > Homo sapiens N EMPECWDGEHD IETPYGLLHV VIRGSPKGNR PAILTYHDVG LNHKLCFNTF FNFEDMQEIT KHFVVCHVDA PGQQVGASQF PQGYQFPSME QLAAMLPSVV QHFGFKYVIG IGVGAGAYVL AKFALIFPDL VEGLVLVNID PNGKGWIDWA ATKLSGLTST LPDTVLSHLF SQEELVNNTE LVQSYRQQIG NVVNQANLQL FWNMYNSRRD LDINRPGTVP NAKTLRCPVM LVVGDNAPAE DGVVECNSKL DPTTTTFLKM ADSGGLPQVT QPGKLTEAFK YFLQGMGYIA YLKDRRLSGG AVPSASMTRL ARSRTASLTS ASSVDGSRPQ ACTHSESSEG LGQVNHTMEV SC
| Title : NDRG4 Alleviates Myocardial Infarction-Induced Apoptosis through the JAK2\/STAT3 Pathway - Zhao_2022_Comput.Math.Methods.Med_2022_4869470 |
| Author(s) : Zhao C , Ren Y , Zhang Y |
| Ref : Comput Math Methods Med , 2022 :4869470 , 2022 |
| Abstract : |
| PubMedSearch : Zhao_2022_Comput.Math.Methods.Med_2022_4869470 |
| PubMedID: 35126626 |
| Gene_locus related to this paper: human-NDRG4 |
| Title : A loss-of-function mutation p.T256M in NDRG4 is implicated in the pathogenesis of pulmonary atresia with ventricular septal defect (PA\/VSD) and tetralogy of Fallot (TOF) - Peng_2021_FEBS.Open.Bio_11_375 |
| Author(s) : Peng J , Wang Q , Meng Z , Wang J , Zhou Y , Zhou S , Song W , Chen S , Chen AF , Sun K |
| Ref : FEBS Open Bio , 11 :375 , 2021 |
| Abstract : |
| PubMedSearch : Peng_2021_FEBS.Open.Bio_11_375 |
| PubMedID: 33211401 |
| Gene_locus related to this paper: human-NDRG4 |
| Title : Identification of NDRG Family Member 4 (NDRG4) and CDC28 Protein Kinase Regulatory Subunit 2 (CKS2) as Key Prognostic Genes in Adrenocortical Carcinoma by Transcriptomic Analysis - Yang_2021_Med.Sci.Monit_27_e928523 |
| Author(s) : Yang Z , Cheng H , Zhang Y , Zhou Y |
| Ref : Med Sci Monit , 27 :e928523 , 2021 |
| Abstract : |
| PubMedSearch : Yang_2021_Med.Sci.Monit_27_e928523 |
| PubMedID: 33667214 |
| Gene_locus related to this paper: human-NDRG4 |
| Title : Hypermethylation-mediated silencing of NDRG4 promotes pancreatic ductal adenocarcinoma by regulating mitochondrial function - Shi_2020_BMB.Rep_53_658 |
| Author(s) : Shi HH , Liu HE , Luo XJ |
| Ref : BMB Rep , 53 :658 , 2020 |
| Abstract : |
| PubMedSearch : Shi_2020_BMB.Rep_53_658 |
| PubMedID: 33298240 |
| Gene_locus related to this paper: human-NDRG4 |
| Title : Exome sequencing identifies a novel homozygous variant in NDRG4 in a family with infantile myofibromatosis (Linhares et al., 2014) turns out to be EBV+ leiomyomatosis caused by CARMIL2 mutations - |
| Author(s) : Linhares ND , Freire MCM , Cardenas R , Pena HB , Bahia M , Pena SDJ |
| Ref : Eur Journal of Medical Genetics , 61 :106 , 2018 |
| PubMedID: 28223207 |
| Gene_locus related to this paper: human-NDRG4 |
| Title : Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing - Yang_2016_Cell_164_805 |
| Author(s) : Yang X , Coulombe-Huntington J , Kang S , Sheynkman GM , Hao T , Richardson A , Sun S , Yang F , Shen YA , Murray RR , Spirohn K , Begg BE , Duran-Frigola M , MacWilliams A , Pevzner SJ , Zhong Q , Trigg SA , Tam S , Ghamsari L , Sahni N , Yi S , Rodriguez MD , Balcha D , Tan G , Costanzo M , Andrews B , Boone C , Zhou XJ , Salehi-Ashtiani K , Charloteaux B , Chen AA , Calderwood MA , Aloy P , Roth FP , Hill DE , Iakoucheva LM , Xia Y , Vidal M |
| Ref : Cell , 164 :805 , 2016 |
| Abstract : |
| PubMedSearch : Yang_2016_Cell_164_805 |
| PubMedID: 26871637 |
| Gene_locus related to this paper: human-NDRG4 |
| Title : Exome sequencing identifies a novel homozygous variant in NDRG4 in a family with infantile myofibromatosis - Linhares_2014_Eur.J.Med.Genet_57_643 |
| Author(s) : Linhares ND , Freire MC , Cardenas RG , Pena HB , Bahia M , Pena SD |
| Ref : Eur Journal of Medical Genetics , 57 :643 , 2014 |
| Abstract : |
| PubMedSearch : Linhares_2014_Eur.J.Med.Genet_57_643 |
| PubMedID: 25241110 |
| Gene_locus related to this paper: human-NDRG4 |
| Title : Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones - Nakajima_2002_DNA.Res_9_99 |
| Author(s) : Nakajima D , Okazaki N , Yamakawa H , Kikuno R , Ohara O , Nagase T |
| Ref : DNA Research , 9 :99 , 2002 |
| Abstract : |
| PubMedSearch : Nakajima_2002_DNA.Res_9_99 |
| PubMedID: 12168954 |
| Gene_locus related to this paper: human-NDRG4 |
| Title : Characterization and expression of three novel differentiation-related genes belong to the human NDRG gene family - Qu_2002_Mol.Cell.Biochem_229_35 |
| Author(s) : Qu X , Zhai Y , Wei H , Zhang C , Xing G , Yu Y , He F |
| Ref : Molecular & Cellular Biochemistry , 229 :35 , 2002 |
| Abstract : |
| PubMedSearch : Qu_2002_Mol.Cell.Biochem_229_35 |
| PubMedID: 11936845 |
| Gene_locus related to this paper: human-NDRG1 , human-NDRG2 , human-NDRG3 , human-NDRG4 |
| Title : Characterization of the human NDRG gene family: a newly identified member, NDRG4, is specifically expressed in brain and heart - Zhou_2001_Genomics_73_86 |
| Author(s) : Zhou RH , Kokame K , Tsukamoto Y , Yutani C , Kato H , Miyata T |
| Ref : Genomics , 73 :86 , 2001 |
| Abstract : |
| PubMedSearch : Zhou_2001_Genomics_73_86 |
| PubMedID: 11352569 |
| Gene_locus related to this paper: human-NDRG2 , human-NDRG3 , human-NDRG4 |
| Title : Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs - Wiemann_2001_Genome.Res_11_422 |
| Author(s) : Wiemann S , Weil B , Wellenreuther R , Gassenhuber J , Glassl S , Ansorge W , Boecher M , Bloecker H , Bauersachs S , Blum H , Lauber J , Duesterhoeft A , Beyer A , Koehrer K , Strack N , Mewes H-W , Ottenwaelder B , Obermaier B , Tampe J , Heubner D , Wambutt R , Korn B , Klein M , Poustka A , Bocher M , Blocker H , Dusterhoft A , Kohrer K , Mewes HW , Ottenwalder B |
| Ref : Genome Res , 11 :422 , 2001 |
| Abstract : |
| PubMedSearch : Wiemann_2001_Genome.Res_11_422 |
| PubMedID: 11230166 |
| Gene_locus related to this paper: human-FAM135A , human-KANSL3 , human-NDRG2 , human-NDRG4 |
| Title : Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain - Hirosawa_1999_DNA.Res_6_329 |
| Author(s) : Hirosawa M , Nagase T , Ishikawa K-I , Kikuno R , Nomura N , Ohara O , Ishikawa K |
| Ref : DNA Research , 6 :329 , 1999 |
| Abstract : |
| PubMedSearch : Hirosawa_1999_DNA.Res_6_329 |
| PubMedID: 10574461 |
| Gene_locus related to this paper: human-NDRG4 |