human-NDRG1

Homo sapiens (Human) N-myc downstream-regulated gene 1 protein (cap43,rit42, ndr1 DRG1, PROXY1, RTP, TDD5)

Comment

NDRG1 appears to play a role in growth arrest and cell differentiation, possibly as a signaling protein shuttling between the cytoplasm and the nucleus. Kalaydjieva et al. (2000)<\/A> demonstrated that expression in peripheral nerve is particularly high in Schwann cells. Taken together, the findings pointed to NDRG1 having a role in the peripheral nervous system, possibly in Schwann cell signaling necessary for axonal survival. Mutation in NDRG1 is responsible for Lom type of hereditary motor and sensory neuropathy also called Charcot-Marie-tooth disease type 4D (Kalaydjieva et al. (2000)<\/A>) (old name human-ndr1) Another gene of the same family ratno-ndr4 (Bdm1) is associated with hot water epilepsy (Bhaduri et al. 2003<\/A>)

Relationship

Family : Ndr_family

Block : X

Position in NCBI Life Tree : Homo sapiens

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Deuterostomia N E > Chordata N E > Craniata N E > Vertebrata N E > Gnathostomata N E > Teleostomi N E > Euteleostomi N E > Sarcopterygii N E > Dipnotetrapodomorpha N E > Tetrapoda N E > Amniota N E > Mammalia N E > Theria N E > Eutheria N E > Boreoeutheria N E > Euarchontoglires N E > Primates N E > Haplorrhini N E > Simiiformes N E > Catarrhini N E > Hominoidea N E > Hominidae N E > Homininae N E > Homo N E > Homo sapiens N E

Molecular evidence

No mutation

No kinetic

No substrate

No inhibitor

Sequence

Peptide

MSREMQDVDL AEVKPLVEKG ETITGLLQEF DVQEQDIETL HGSVHVTLCG TPKGNRPVIL TYHDIGMNHK TCYNPLFNYE DMQEITQHFA VCHVDAPGQQ DGAASFPAGY MYPSMDQLAE MLPGVLQQFG LKSIIGMGTG AGAYILTRFA LNNPEMVEGL VLINVNPCAE GWMDWAASKI SGWTQALPDM VVSHLFGKEE MQSNVEVVHT YRQHIVNDMN PGNLHLFINA YNSRRDLEIE RPMPGTHTVT LQCPALLVVG DSSPAVDAVV ECNSKLDPTK TTLLKMADCG GLPQISQPAK LAEAFKYFVQ GMGYMPSASM TRLMRSRTAS GSSVTSLDGT RSRSHTSEGT RSRSHTSEGT RSRSHTSEGA HLDITPNSGA AGNSAGPKSM EVSC

References (51)

Title : A review on the role of NDRG1 in different cancers - Ghafouri-Fard_2023_Mol.Biol.Rep__
Author(s) : Ghafouri-Fard S , Ahmadi Teshnizi S , Hussen BM , Taheri M , Sharifi G
Ref : Mol Biol Rep , : , 2023
PubMedID: 37249826
Gene_locus related to this paper: human-NDRG1

Title : Exercise increases phosphorylation of the putative mTORC2 activity readout NDRG1 in human skeletal muscle - Knudsen_2022_Am.J.Physiol.Endocrinol.Metab_322_E63
Author(s) : Knudsen JR , Persson KW , Meister J , Carl CS , Raun SH , Andersen NR , Sylow L , Kiens B , Jensen TE , Richter EA , Kleinert M
Ref : American Journal of Physiology Endocrinol Metab , 322 :E63 , 2022
PubMedID: 34866401
Gene_locus related to this paper: human-NDRG1

Title : NDRG1 facilitates lytic replication of Kaposi's sarcoma-associated herpesvirus by maintaining the stability of the KSHV helicase - Dong_2021_PLoS.Pathog_17_e1009645
Author(s) : Dong L , Dong J , Xiang M , Lei P , Li Z , Zhang F , Sun X , Niu D , Bai L , Lan K
Ref : PLoS Pathog , 17 :e1009645 , 2021
PubMedID: 34077484
Gene_locus related to this paper: human-NDRG1

Title : The expression of YWHAZ and NDRG1 predicts aggressive outcome in human prostate cancer - Lage-Vickers_2021_Commun.Biol_4_103
Author(s) : Lage-Vickers S , Bizzotto J , Valacco MP , Sanchis P , Nemirovsky S , Labanca E , Scorticati C , Mazza O , Mitrofanova A , Navone N , Vazquez E , Cotignola J , Gueron G
Ref : Commun Biol , 4 :103 , 2021
PubMedID: 33483585
Gene_locus related to this paper: human-NDRG1

Title : Crystal and solution structure of NDRG1, a membrane-binding protein linked to myelination and tumour suppression - Mustonen_2021_FEBS.J_288_3507
Author(s) : Mustonen V , Muruganandam G , Loris R , Kursula P , Ruskamo S
Ref : Febs J , 288 :3507 , 2021
PubMedID: 33305529
Gene_locus related to this paper: human-NDRG1

Title : MiR-188-3p and miR-133b Suppress Cell Proliferation in Human Hepatocellular Carcinoma via Post-Transcriptional Suppression of NDRG1 - Luo_2021_Technol.Cancer.Res.Treat_20_15330338211033074
Author(s) : Luo Z , Fan Y , Liu X , Liu S , Kong X , Ding Z , Li Y , Wei L
Ref : Technol Cancer Research Treat , 20 :15330338211033074 , 2021
PubMedID: 34355586
Gene_locus related to this paper: human-NDRG1

Title : A novel homozygous NDRG1 mutation in a Chinese patient with Charcot-Marie-Tooth disease 4D - Chen_2018_J.Clin.Neurosci_53_231
Author(s) : Chen B , Niu S , Chen N , Pan H , Wang X , Zhang Z
Ref : J Clin Neurosci , 53 :231 , 2018
PubMedID: 29724652
Gene_locus related to this paper: human-NDRG1

Title : A novel NDRG1 mutation in a non-Romani patient with CMT4D\/HMSN-Lom - Piscosquito_2017_J.Peripher.Nerv.Syst_22_47
Author(s) : Piscosquito G , Magri S , Saveri P , Milani M , Ciano C , Farina L , Taroni F , Pareyson D
Ref : J Peripher Nerv Syst , 22 :47 , 2017
PubMedID: 27982524
Gene_locus related to this paper: human-NDRG1

Title : Identification and functional characterization of two missense mutations in NDRG1 associated with Charcot-Marie-Tooth disease type 4D - Li_2017_Hum.Mutat_38_1569
Author(s) : Li LX , Liu GL , Liu ZJ , Lu C , Wu ZY
Ref : Hum Mutat , 38 :1569 , 2017
PubMedID: 28776325
Gene_locus related to this paper: human-NDRG1

Title : Frequent genes in rare diseases: panel-based next generation sequencing to disclose causal mutations in hereditary neuropathies - Dohrn_2017_J.Neurochem_143_507
Author(s) : Dohrn MF , Glockle N , Mulahasanovic L , Heller C , Mohr J , Bauer C , Riesch E , Becker A , Battke F , Hortnagel K , Hornemann T , Suriyanarayanan S , Blankenburg M , Schulz JB , Claeys KG , Gess B , Katona I , Ferbert A , Vittore D , Grimm A , Wolking S , Schols L , Lerche H , Korenke GC , Fischer D , Schrank B , Kotzaeridou U , Kurlemann G , Drager B , Schirmacher A , Young P , Schlotter-Weigel B , Biskup S
Ref : Journal of Neurochemistry , 143 :507 , 2017
PubMedID: 28902413
Gene_locus related to this paper: human-NDRG1

Title : Ndrg1 promotes adipocyte differentiation and sustains their function - Cai_2017_Sci.Rep_7_7191
Author(s) : Cai K , El-Merahbi R , Loeffler M , Mayer AE , Sumara G
Ref : Sci Rep , 7 :7191 , 2017
PubMedID: 28775290
Gene_locus related to this paper: human-NDRG1

Title : N-myc downstream regulated gene 1(NDRG1) promotes the stem-like properties of lung cancer cells through stabilized c-Myc - Wang_2017_Cancer.Lett_401_53
Author(s) : Wang Y , Zhou Y , Tao F , Chai S , Xu X , Yang Y , Xu H , Wang K
Ref : Cancer Letters , 401 :53 , 2017
PubMedID: 28456659
Gene_locus related to this paper: human-NDRG1

Title : The metastatic suppressor NDRG1 inhibits EMT, migration and invasion through interaction and promotion of caveolin-1 ubiquitylation in human colorectal cancer cells - Mi_2017_Oncogene_36_4323
Author(s) : Mi L , Zhu F , Yang X , Lu J , Zheng Y , Zhao Q , Wen X , Lu A , Wang M , Zheng M , Ji J , Sun J
Ref : Oncogene , 36 :4323 , 2017
PubMedID: 28346422
Gene_locus related to this paper: human-NDRG1

Title : N-myc downstream-regulated gene 1 promotes oxaliplatin-triggered apoptosis in colorectal cancer cells via enhancing the ubiquitination of Bcl-2 - Yang_2017_Oncotarget_8_47709
Author(s) : Yang X , Zhu F , Yu C , Lu J , Zhang L , Lv Y , Sun J , Zheng M
Ref : Oncotarget , 8 :47709 , 2017
PubMedID: 28537875
Gene_locus related to this paper: human-NDRG1

Title : Low Levels of NDRG1 in Nerve Tissue Are Predictive of Severe Paclitaxel-Induced Neuropathy - Sundar_2016_PLoS.One_11_e0164319
Author(s) : Sundar R , Jeyasekharan AD , Pang B , Soong RC , Kumarakulasinghe NB , Ow SG , Ho J , Lim JS , Tan DS , Wilder-Smith EP , Bandla A , Tan SS , Asuncion BR , Fazreen Z , Hoppe MM , Putti TC , Poh LM , Goh BC , Lee SC
Ref : PLoS ONE , 11 :e0164319 , 2016
PubMedID: 27716814
Gene_locus related to this paper: human-NDRG1

Title : Clinical, electrophysiological and pathological findings in a patient with Charcot-Marie-Tooth disease 4D caused by the NDRG1 Lom mutation -
Author(s) : Luigetti M , Taroni F , Milani M , Del Grande A , Romano A , Bisogni G , Conte A , Contaldo I , Mercuri E , Sabatelli M
Ref : Journal of Neurology Sci , 345 :271 , 2014
PubMedID: 25108819
Gene_locus related to this paper: human-NDRG1

Title : Exonic duplication CNV of NDRG1 associated with autosomal-recessive HMSN-Lom\/CMT4D - Okamoto_2014_Genet.Med_16_386
Author(s) : Okamoto Y , Goksungur MT , Pehlivan D , Beck CR , Gonzaga-Jauregui C , Muzny DM , Atik MM , Carvalho CM , Matur Z , Bayraktar S , Boone PM , Akyuz K , Gibbs RA , Battaloglu E , Parman Y , Lupski JR
Ref : Genet Med , 16 :386 , 2014
PubMedID: 24136616
Gene_locus related to this paper: human-NDRG1

Title : Genetics of the Charcot-Marie-Tooth disease in the Spanish Gypsy population: the hereditary motor and sensory neuropathy-Russe in depth - Sevilla_2013_Clin.Genet_83_565
Author(s) : Sevilla T , Martinez-Rubio D , Marquez C , Paradas C , Colomer J , Jaijo T , Millan J , Palau F , Espinos C , Millan JM
Ref : Clin Genet , 83 :565 , 2013
PubMedID: 22978647
Gene_locus related to this paper: human-NDRG1

Title : The expression and localization of N-myc downstream-regulated gene 1 in human trophoblasts - Shi_2013_PLoS.One_8_e75473
Author(s) : Shi XH , Larkin JC , Chen B , Sadovsky Y
Ref : PLoS ONE , 8 :e75473 , 2013
PubMedID: 24066183
Gene_locus related to this paper: human-NDRG1

Title : The stretcher spontaneous neurodegenerative mutation models Charcot-Marie-Tooth disease type 4D - Chandler_2013_F1000Res_2_46
Author(s) : Chandler D , Lopaticki S , Huang D , Hunter M , Angelicheva D , Kilpatrick T , King RH , Kalaydjieva L , Morahan G
Ref : F1000Res , 2 :46 , 2013
PubMedID: 24715951
Gene_locus related to this paper: human-NDRG1 , mouse-ndr1

Title : CMT4D (NDRG1 mutation): genotype-phenotype correlations - Ricard_2013_J.Peripher.Nerv.Syst_18_261
Author(s) : Ricard E , Mathis S , Magdelaine C , Delisle MB , Magy L , Funalot B , Vallat JM
Ref : J Peripher Nerv Syst , 18 :261 , 2013
PubMedID: 24028195
Gene_locus related to this paper: human-NDRG1

Title : Inhibition of N-Myc down regulated gene 1 in in vitro cultured human glioblastoma cells - Said_2012_World.J.Clin.Oncol_3_104
Author(s) : Said HM , Polat B , Stein S , Guckenberger M , Hagemann C , Staab A , Katzer A , Anacker J , Flentje M , Vordermark D
Ref : World J Clin Oncol , 3 :104 , 2012
PubMedID: 22787578
Gene_locus related to this paper: human-NDRG1

Title : Differentiation-related gene-1 decreases Bim stability by proteasome-mediated degradation - Ambrosini_2009_Cancer.Res_69_6115
Author(s) : Ambrosini G , Seelman SL , Schwartz GK
Ref : Cancer Research , 69 :6115 , 2009
PubMedID: 19622774
Gene_locus related to this paper: human-NDRG1

Title : Hereditary motor and sensory neuropathy Lom type in a Serbian family - Dackovic_2008_Acta.Myol_27_59
Author(s) : Dackovic J , Keckarevic-Markovic M , Komazec Z , Rakocevic-Stojanovic V , Lavrnic D , Stevic Z , Ribaric K , Romac S , Apostolski S
Ref : Acta Myol , 27 :59 , 2008
PubMedID: 19364063
Gene_locus related to this paper: human-NDRG1

Title : The p.R1109X mutation in SH3TC2 gene is predominant in Spanish Gypsies with Charcot-Marie-Tooth disease type 4 - Claramunt_2007_Clin.Genet_71_343
Author(s) : Claramunt R , Sevilla T , Lupo V , Cuesta A , Millan JM , Vilchez JJ , Palau F , Espinos C
Ref : Clin Genet , 71 :343 , 2007
PubMedID: 17470135
Gene_locus related to this paper: human-NDRG1

Title : NDRG1-linked Charcot-Marie-Tooth disease (CMT4D) with central nervous system involvement - Echaniz-Laguna_2007_Neuromuscul.Disord_17_163
Author(s) : Echaniz-Laguna A , Degos B , Bonnet C , Latour P , Hamadouche T , Levy N , Leheup B
Ref : Neuromuscular Disorders , 17 :163 , 2007
PubMedID: 17142040
Gene_locus related to this paper: human-NDRG1

Title : 17Beta-estradiol induces down-regulation of Cap43\/NDRG1\/Drg-1, a putative differentiation-related and metastasis suppressor gene, in human breast cancer cells - Fotovati_2006_Clin.Cancer.Res_12_3010
Author(s) : Fotovati A , Fujii T , Yamaguchi M , Kage M , Shirouzu K , Oie S , Basaki Y , Ono M , Yamana H , Kuwano M
Ref : Clin Cancer Research , 12 :3010 , 2006
PubMedID: 16707596
Gene_locus related to this paper: human-NDRG1

Title : Cellular differentiation determines the expression of the hypoxia-inducible protein NDRG1 in pancreatic cancer - Angst_2006_Br.J.Cancer_95_307
Author(s) : Angst E , Sibold S , Tiffon C , Weimann R , Gloor B , Candinas D , Stroka D
Ref : Br J Cancer , 95 :307 , 2006
PubMedID: 16832411
Gene_locus related to this paper: human-NDRG1

Title : Tumor growth suppression in pancreatic cancer by a putative metastasis suppressor gene Cap43\/NDRG1\/Drg-1 through modulation of angiogenesis - Maruyama_2006_Cancer.Res_66_6233
Author(s) : Maruyama Y , Ono M , Kawahara A , Yokoyama T , Basaki Y , Kage M , Aoyagi S , Kinoshita H , Kuwano M
Ref : Cancer Research , 66 :6233 , 2006
PubMedID: 16778198
Gene_locus related to this paper: human-NDRG1

Title : Complete sequencing and characterization of 21,243 full-length human cDNAs - Ota_2004_Nat.Genet_36_40
Author(s) : Ota T , Suzuki Y , Nishikawa T , Otsuki T , Sugiyama T , Irie R , Wakamatsu A , Hayashi K , Sato H , Nagai K , Kimura K , Makita H , Sekine M , Obayashi M , Nishi T , Shibahara T , Tanaka T , Ishii S , Yamamoto J , Saito K , Kawai Y , Isono Y , Nakamura Y , Nagahari K , Murakami K , Yasuda T , Iwayanagi T , Wagatsuma M , Shiratori A , Sudo H , Hosoiri T , Kaku Y , Kodaira H , Kondo H , Sugawara M , Takahashi M , Kanda K , Yokoi T , Furuya T , Kikkawa E , Omura Y , Abe K , Kamihara K , Katsuta N , Sato K , Tanikawa M , Yamazaki M , Ninomiya K , Ishibashi T , Yamashita H , Murakawa K , Fujimori K , Tanai H , Kimata M , Watanabe M , Hiraoka S , Chiba Y , Ishida S , Ono Y , Takiguchi S , Watanabe S , Yosida M , Hotuta T , Kusano J , Kanehori K , Takahashi-Fujii A , Hara H , Tanase TO , Nomura Y , Togiya S , Komai F , Hara R , Takeuchi K , Arita M , Imose N , Musashino K , Yuuki H , Oshima A , Sasaki N , Aotsuka S , Yoshikawa Y , Matsunawa H , Ichihara T , Shiohata N , Sano S , Moriya S , Momiyama H , Satoh N , Takami S , Terashima Y , Suzuki O , Nakagawa S , Senoh A , Mizoguchi H , Goto Y , Shimizu F , Wakebe H , Hishigaki H , Watanabe T , Sugiyama A , Takemoto M , Kawakami B , Watanabe K , Kumagai A , Itakura S , Fukuzumi Y , Fujimori Y , Komiyama M , Tashiro H , Tanigami A , Fujiwara T , Ono T , Yamada K , Fujii Y , Ozaki K , Hirao M , Ohmori Y , Kawabata A , Hikiji T , Kobatake N , Inagaki H , Ikema Y , Okamoto S , Okitani R , Kawakami T , Noguchi S , Itoh T , Shigeta K , Senba T , Matsumura K , Nakajima Y , Mizuno T , Morinaga M , Sasaki M , Togashi T , Oyama M , Hata H , Komatsu T , Mizushima-Sugano J , Satoh T , Shirai Y , Takahashi Y , Nakagawa K , Okumura K , Nagase T , Nomura N , Kikuchi H , Masuho Y , Yamashita R , Nakai K , Yada T , Ohara O , Isogai T , Sugano S
Ref : Nat Genet , 36 :40 , 2004
PubMedID: 14702039
Gene_locus related to this paper: human-ABHD1 , human-ABHD4 , human-ABHD12 , human-ABHD16A , human-ACOT1 , human-LDAH , human-ABHD18 , human-CES1 , human-CES4A , human-CES5A , human-CPVL , human-DAGLB , human-EPHX2 , human-KANSL3 , human-LIPA , human-LPL , human-MEST , human-NDRG1 , human-NLGN1 , human-NLGN4X , human-PRCP , human-PRSS16 , human-SERAC1 , human-TMEM53

Title : NDRG1 is necessary for p53-dependent apoptosis - Stein_2004_J.Biol.Chem_279_48930
Author(s) : Stein S , Thomas EK , Herzog B , Westfall MD , Rocheleau JV , Jackson RS, 2nd , Wang M , Liang P
Ref : Journal of Biological Chemistry , 279 :48930 , 2004
PubMedID: 15377670
Gene_locus related to this paper: human-NDRG1

Title : Hypoxia upregulates the expression of the NDRG1 gene leading to its overexpression in various human cancers - Cangul_2004_BMC.Genet_5_27
Author(s) : Cangul H
Ref : BMC Genet , 5 :27 , 2004
PubMedID: 15341671
Gene_locus related to this paper: human-NDRG1

Title : N-myc downstream-regulated gene 1 expression in injured sciatic nerves - Hirata_2004_Glia_47_325
Author(s) : Hirata K , Masuda K , Morikawa W , He JW , Kuraoka A , Kuwano M , Kawabuchi M
Ref : Glia , 47 :325 , 2004
PubMedID: 15293230
Gene_locus related to this paper: human-NDRG1

Title : Association of N-myc downregulated gene 1 with heat-shock cognate protein 70 in mast cells - Sugiki_2004_Biol.Pharm.Bull_27_628
Author(s) : Sugiki T , Taketomi Y , Kikuchi-Yanoshita R , Murakami M , Kudo I
Ref : Biol Pharm Bull , 27 :628 , 2004
PubMedID: 15133235
Gene_locus related to this paper: human-NDRG1

Title : Expression analysis of the N-Myc downstream-regulated gene 1 indicates that myelinating Schwann cells are the primary disease target in hereditary motor and sensory neuropathy-Lom - Berger_2004_Neurobiol.Dis_17_290
Author(s) : Berger P , Sirkowski EE , Scherer SS , Suter U
Ref : Neurobiol Dis , 17 :290 , 2004
PubMedID: 15474366
Gene_locus related to this paper: human-NDRG1

Title : N-myc downregulated gene 1 is a phosphorylated protein in mast cells - Sugiki_2004_Biol.Pharm.Bull_27_624
Author(s) : Sugiki T , Murakami M , Taketomi Y , Kikuchi-Yanoshita R , Kudo I
Ref : Biol Pharm Bull , 27 :624 , 2004
PubMedID: 15133234
Gene_locus related to this paper: human-NDRG1

Title : Correlation of N-myc downstream-regulated gene 1 overexpression with progressive growth of colorectal neoplasm - Wang_2004_World.J.Gastroenterol_10_550
Author(s) : Wang Z , Wang F , Wang WQ , Gao Q , Wei WL , Yang Y , Wang GY
Ref : World J Gastroenterol , 10 :550 , 2004
PubMedID: 14966915
Gene_locus related to this paper: human-NDRG1

Title : The growth-inhibitory Ndrg1 gene is a Myc negative target in human neuroblastomas and other cell types with overexpressed N- or c-myc - Li_2003_Mol.Cell.Biochem_250_91
Author(s) : Li J , Kretzner L
Ref : Molecular & Cellular Biochemistry , 250 :91 , 2003
PubMedID: 12962147
Gene_locus related to this paper: human-NDRG1

Title : Mutation screening of the N-myc downstream-regulated gene 1 (NDRG1) in patients with Charcot-Marie-Tooth Disease - Hunter_2003_Hum.Mutat_22_129
Author(s) : Hunter M , Bernard R , Freitas E , Boyer A , Morar B , Martins IJ , Tournev I , Jordanova A , Guergelcheva V , Ishpekova B , Kremensky I , Nicholson G , Schlotter B , Lochmuller H , Voit T , Colomer J , Thomas PK , Levy N , Kalaydjieva L
Ref : Hum Mutat , 22 :129 , 2003
PubMedID: 12872253
Gene_locus related to this paper: human-NDRG1

Title : Identification of NDRG1 as an early inducible gene during in vitro maturation of cultured mast cells - Taketomi_2003_Biochem.Biophys.Res.Commun_306_339
Author(s) : Taketomi Y , Sugiki T , Saito T , Ishii S , Hisada M , Suzuki-Nishimura T , Uchida MK , Moon TC , Chang HW , Natori Y , Miyazawa S , Kikuchi-Yanoshita R , Murakami M , Kudo I
Ref : Biochemical & Biophysical Research Communications , 306 :339 , 2003
PubMedID: 12804568
Gene_locus related to this paper: human-NDRG1

Title : The Drg-1 gene suppresses tumor metastasis in prostate cancer - Bandyopadhyay_2003_Cancer.Res_63_1731
Author(s) : Bandyopadhyay S , Pai SK , Gross SC , Hirota S , Hosobe S , Miura K , Saito K , Commes T , Hayashi S , Watabe M , Watabe K
Ref : Cancer Research , 63 :1731 , 2003
PubMedID: 12702552
Gene_locus related to this paper: human-NDRG1

Title : Expression of NDRG1, a differentiation-related gene, in human tissues - Lachat_2002_Histochem.Cell.Biol_118_399
Author(s) : Lachat P , Shaw P , Gebhard S , van Belzen N , Chaubert P , Bosman FT
Ref : Histochemistry & Cell Biology , 118 :399 , 2002
PubMedID: 12432451
Gene_locus related to this paper: human-NDRG1

Title : Characterization and expression of three novel differentiation-related genes belong to the human NDRG gene family - Qu_2002_Mol.Cell.Biochem_229_35
Author(s) : Qu X , Zhai Y , Wei H , Zhang C , Xing G , Yu Y , He F
Ref : Molecular & Cellular Biochemistry , 229 :35 , 2002
PubMedID: 11936845
Gene_locus related to this paper: human-NDRG1 , human-NDRG2 , human-NDRG3 , human-NDRG4

Title : The regulation of hypoxic genes by calcium involves c-Jun\/AP-1, which cooperates with hypoxia-inducible factor 1 in response to hypoxia - Salnikow_2002_Mol.Cell.Biol_22_1734
Author(s) : Salnikow K , Kluz T , Costa M , Piquemal D , Demidenko ZN , Xie K , Blagosklonny MV
Ref : Molecular & Cellular Biology , 22 :1734 , 2002
PubMedID: 11865053
Gene_locus related to this paper: human-NDRG1

Title : N-myc downstream-regulated gene 1 is mutated in hereditary motor and sensory neuropathy-Lom - Kalaydjieva_2000_Am.J.Hum.Genet_67_47
Author(s) : Kalaydjieva L , Gresham D , Gooding R , Heather L , Baas F , de Jonge R , Blechschmidt K , Angelicheva D , Chandler D , Worsley P , Rosenthal A , King RH , Thomas PK
Ref : American Journal of Human Genetics , 67 :47 , 2000
PubMedID: 10831399
Gene_locus related to this paper: human-NDRG1

Title : Drg-1 as a differentiation-related, putative metastatic suppressor gene in human colon cancer - Guan_2000_Cancer.Res_60_749
Author(s) : Guan RJ , Ford HL , Fu Y , Li Y , Shaw LM , Pardee AB
Ref : Cancer Research , 60 :749 , 2000
PubMedID: 10676663
Gene_locus related to this paper: human-NDRG1

Title : Differential expression of the RTP\/Drg1\/Ndr1 gene product in proliferating and growth arrested cells - Piquemal_1999_Biochim.Biophys.Acta_1450_364
Author(s) : Piquemal D , Joulia D , Balaguer P , Basset A , Marti J , Commes T
Ref : Biochimica & Biophysica Acta , 1450 :364 , 1999
PubMedID: 10395947
Gene_locus related to this paper: human-NDRG1

Title : Cap43, a novel gene specifically induced by Ni2+ compounds - Zhou_1998_Cancer.Res_58_2182
Author(s) : Zhou D , Salnikow K , Costa M
Ref : Cancer Research , 58 :2182 , 1998
PubMedID: 9605764
Gene_locus related to this paper: human-NDRG1

Title : Inhibition of tumor cell growth by RTP\/rit42 and its responsiveness to p53 and DNA damage - Kurdistani_1998_Cancer.Res_58_4439
Author(s) : Kurdistani SK , Arizti P , Reimer CL , Sugrue MM , Aaronson SA , Lee SW
Ref : Cancer Research , 58 :4439 , 1998
PubMedID: 9766676
Gene_locus related to this paper: human-NDRG1

Title : A novel gene which is up-regulated during colon epithelial cell differentiation and down-regulated in colorectal neoplasms - van Belzen_1997_Lab.Invest_77_85
Author(s) : van Belzen N , Dinjens WNM , Diesveld MPG , Groen NA , van der Made ACJ , Nozawa Y , Vlietstra R , Trapman J , Bosman FT , Dinjens WN , Diesveld MP , van der Made AC
Ref : Lab Invest , 77 :85 , 1997
PubMedID: 9251681
Gene_locus related to this paper: human-NDRG1

Title : Homocysteine-respondent genes in vascular endothelial cells identified by differential display analysis. GRP78\/BiP and novel genes - Kokame_1996_J.Biol.Chem_271_29659
Author(s) : Kokame K , Kato H , Miyata T
Ref : Journal of Biological Chemistry , 271 :29659 , 1996
PubMedID: 8939898
Gene_locus related to this paper: human-NDRG1