CMP
General
Type : Organophosphate, Surrogate OP, Chromen
Chemical_Nomenclature : 7-[cyclohexyloxy(methyl)phosphoryl]oxy-4-methyl-2-oxochromene-3-carbonitrile
Canonical SMILES : CC1=C(C(=O)OC2=C1C=CC(=C2)OP(=O)(C)OC3CCCCC3)C#N
InChI : InChI=1S\/C18H20NO5P\/c1-12-15-9-8-14(10-17(15)22-18(20)16(12)11-19)24-25(2,21)23-13-6-4-3-5-7-13\/h8-10,13H,3-7H2,1-2H3
InChIKey : TVZHLDDYQNBRID-UHFFFAOYSA-N
Other name(s) : 3-Cyano-4-methyl-2-oxo-2H-coumarin-7-ylcyclohexyl methylphosphonate
MW : 361.3
Formula : C18H20NO5P
CAS_number :
PubChem : 49795038
UniChem : TVZHLDDYQNBRID-UHFFFAOYSA-N
Target
Families : CMP ligand of proteins in family
ACHE
Protein :
human-ACHE
References (2)
| Title : Imidazole as a Pendant Reactivation Ligand Increases Efficacy Scope for Reactivation and Resurrection of Organophosphorus-Inhibited\/Aged Cholinesterases by Quinone Methide Precursors - Lovins_2026_ACS.Chem.Neurosci__ |
| Author(s) : Lovins AR , Miller KA , Homoelle RK , Hoover HJ , McElroy CA , Callam CS , Hadad CM |
| Ref : ACS Chem Neurosci , : , 2026 |
| Abstract : |
| PubMedSearch : Lovins_2026_ACS.Chem.Neurosci__ |
| PubMedID: 41712538 |
| Title : Directed evolution of hydrolases for prevention of G-type nerve agent intoxication - Gupta_2011_Nat.Chem.Biol_7_120 |
| Author(s) : Gupta RD , Goldsmith M , Ashani Y , Simo Y , Mullokandov G , Bar H , Ben-David M , Leader H , Margalit R , Silman I , Sussman JL , Tawfik DS |
| Ref : Nat Chemical Biology , 7 :120 , 2011 |
| Abstract : |
| PubMedSearch : Gupta_2011_Nat.Chem.Biol_7_120 |
| PubMedID: 21217689 |