E1K

General

Type : Derivative of Tacrine

Chemical_Nomenclature : 6-chloranyl-10-methyl-1,2,3,4-tetrahydroacridin-10-ium-9-amine

Canonical SMILES : C[n+]1c2CCCCc2c(N)c2ccc(Cl)cc12

InChI : InChI=1S\/C14H15ClN2\/c1-17-12-5-3-2-4-10(12)14(16)11-7-6-9(15)8-13(11)17\/h6-8,16H,2-5H2,1H3\/p+1

InChIKey : NNLSQYGKFPZYHI-UHFFFAOYSA-O

Other name(s) :


MW : 247.74

Formula : C14H16ClN2

CAS_number :

PubChem : 132472270

UniChem : NNLSQYGKFPZYHI-UHFFFAOYSA-O

Target

Families : E1K ligand of proteins in family
ACHE

Structure :
6G1U

Protein :
torca-ACHE

References (1)

Title : Increasing Polarity in Tacrine and Huprine Derivatives: Potent Anticholinesterase Agents for the Treatment of Myasthenia Gravis - Galdeano_2018_Molecules_23_
Author(s) : Galdeano C , Coquelle N , Cieslikiewicz-Bouet M , Bartolini M , Perez B , Clos MV , Silman I , Jean L , Colletier JP , Renard PY , Munoz-Torrero D
Ref : Molecules , 23 : , 2018
Abstract :
PubMedSearch : Galdeano_2018_Molecules_23_
PubMedID: 29534488
Gene_locus related to this paper: torca-ACHE