SCHEMBL1532301
General
Type : Indole, Isoindole, Acridine, Alkyl linked bis-ligand, Derivative of Tacrine, Derivative of Donepezil
Chemical_Nomenclature : N-[3-[3-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]propyl-methylamino]propyl]-2-(1,3-dioxoisoindol-2-yl)acetamide
Canonical SMILES : CN(CCCNC1=C2CCCCC2=NC3=C1C=CC(=C3)Cl)CCCNC(=O)CN4C(=O)C5=CC=CC=C5C4=O
InChI : InChI=1S\/C30H34ClN5O3\/c1-35(16-6-14-32-27(37)19-36-29(38)21-8-2-3-9-22(21)30(36)39)17-7-15-33-28-23-10-4-5-11-25(23)34-26-18-20(31)12-13-24(26)28\/h2-3,8-9,12-13,18H,4-7,10-11,14-17,19H2,1H3,(H,32,37)(H,33,34)
InChIKey : ISOAVSDSNXGYJJ-UHFFFAOYSA-N
Other name(s) :
MW : 548.1
Formula : C30H34ClN5O3
CAS_number :
PubChem : 17989634
UniChem : ISOAVSDSNXGYJJ-UHFFFAOYSA-N
Target
Families : SCHEMBL1532301 ligand of proteins in family
ACHE
References (1)
| Title : Donepezil-tacrine hybrid related derivatives as new dual binding site inhibitors of AChE - Alonso_2005_Bioorg.Med.Chem_13_6588 |
| Author(s) : Alonso D , Dorronsoro I , Rubio L , Munoz P , Garcia-Palomero E , del Monte M , Bidon-Chanal A , Orozco M , Luque FJ , Castro A , Medina M , Martinez A |
| Ref : Bioorganic & Medicinal Chemistry , 13 :6588 , 2005 |
| Abstract : |
| PubMedSearch : Alonso_2005_Bioorg.Med.Chem_13_6588 |
| PubMedID: 16230018 |