Isoindole

General

Fusion of benzene and pyrazole. Building block for many inhibitors of enzymes. Indole is an analog with only one nitrogen atom in position 1. Building block for many inhibitors of enzymes
Inhibitor Main targeted enzyme familyes Type Structure
SCHEMBL1532301 ACHE Indole Isoindole Acridine Alkyl linked bis-ligand Derivative of Tacrine Derivative of Donepezil
Allo-Ile-isoindoline DPP4N_Peptidase_S9 Isoindole
6H12-(R)2 ACHE Derivative of Tacrine Derivative of Valmerin Urea derivative GSK-3 kinase inhibitor Multitarget Isoindole Indole Triazol
6H13-(R)3 ACHE Derivative of Tacrine Derivative of Valmerin Urea derivative GSK-3 kinase inhibitor Multitarget Isoindole Indole Triazol
6H14-(S)6 ACHE Derivative of Tacrine Derivative of Valmerin Urea derivative GSK-3 kinase inhibitor Multitarget Isoindole Indole Triazol
R-Pro-(decarboxy-Pro)-X99 S9N_PPCE_Peptidase_S9 Pyrrolidine Isoindole Indole
Nijmegen-1 RsbQ-like Cotylimide Strigolactone receptors ligand Isoindole Indole Butenolide Phthalimido
isoquinolinederivative18 DPP4N_Peptidase_S9 Piperazine Isoindole Indole
1G244 DPP4N_Peptidase_S9 Piperazine Isoindole Indole
Phthalimido-Galanthaminium-4d ACHE Derivative of Galanthamine Alkaloid Natural_modified Alkyl linked bis-ligand Isoindole Phthalimido Benzazepin Azepine
Phthalimido-Galanthaminium-8d ACHE Derivative of Galanthamine Alkaloid Natural_modified Alkyl linked bis-ligand Isoindole Indole Phthalimido Benzazepin Azepine
Dialifor-oxon ACHE Organophosphate Insecticide Isoindole Indole Sulfur Compound
Dialifor ACHE Organophosphate Insecticide Isoindole Indole Sulfur Compound
PIMP ACHE Organophosphate Surrogate OP Nerve Agent G-series Derivative of Sarin Phthalimido Isoindole
Phosmet ACHE Organophosphate Insecticide Sulfur Compound Organothiophosphate Isoindole Indole
Phosmetoxon ACHE Organophosphate Insecticide Sulfur Compound Organothiophosphate Isoindole Indole Phthalimido