SCHEMBL31034887
human butyrylcholinesterase pseudo-irreversible inhibitor and slow substrate, precursor of a nanomolar selective alpha 2-adrenergic antagonist atipamezole
General
Type : Imidazole, Carboxamide, Indole, Inden, Adrenergic-Receptor-ligand, Pro-Drug
Chemical_Nomenclature : N,N-diethyl-4-(2-ethyl-1,3-dihydroinden-2-yl)imidazole-1-carboxamide
Canonical SMILES : CCC1(CC2=CC=CC=C2C1)C3=CN(C=N3)C(=O)N(CC)CC
InChI : InChI=1S\/C19H25N3O\/c1-4-19(11-15-9-7-8-10-16(15)12-19)17-13-22(14-20-17)18(23)21(5-2)6-3\/h7-10,13-14H,4-6,11-12H2,1-3H3
InChIKey : ONLXATXJFCFKHZ-UHFFFAOYSA-N
Other name(s) : N,N-Diethyl-4-(2-ethylindan-2-yl)-1H-imidazole-1-carboxamide
MW : 311.4
Formula : C19H25N3O
CAS_number :
PubChem : 172255854
UniChem : ONLXATXJFCFKHZ-UHFFFAOYSA-N
Target
Families : SCHEMBL31034887 ligand of proteins in family
BCHE
Protein :
human-BCHE
References (1)
| Title : Pleiotropic prodrugs for both symptomatic and disease-modifying treatment of Alzheimer's disease - Meden_2025_Acta.Pharm.Sin.B_15_4807 |
| Author(s) : Meden A , Znidarsic N , Knez D , Wang Y , Xu Z , Yang H , Zhang W , Pislar A , Perdih A , Brezar SK , Grgurevic N , Pajk S , Sun H , Gobec S |
| Ref : Acta Pharm Sin B , 15 :4807 , 2025 |
| Abstract : |
| PubMedSearch : Meden_2025_Acta.Pharm.Sin.B_15_4807 |
| PubMedID: 41049759 |