30GY
Name : Structure of recombinant human BChE in complex with (1-benzylpyrrolidin-3-yl)methyl N-(2-methylphenyl)carbamate Compound 14 (S)-(+)-14
Revelation date : 07-Oct-2026
Family : BCHE
Gene_locus : human-BCHE
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Brazzolotto, X.,Mastnak-Sokolov, P.,Kozak, U.,Gobec, S.,Nachon, F. 2026-04-24
Ligand : Inhibitor Benzylpyrrolidin-methyl-o-tolylcarbamate Ligand in structure: Ligplot
References (1)
| Title : Structure-Guided Design of a Brain-Penetrant Covalent Inhibitor of Human Butyrylcholinesterase with In Vivo Procognitive Efficacy - Mastnak-Sokolov_2026_J.Med.Chem__ |
| Author(s) : Mastnak-Sokolov Mastnak-Sokolov P , Kosak U , Meden Ae , Knez D , Zakelj S , Horvat S , Pislar A , Kljun J , Igert A , Dias J , Nachon F , Brazzolotto X , Novak M , Rydlova V , Karasova JZ , Soukup O , Manik A , Detka J , Salat K , Gobec S |
| Ref : Journal of Medicinal Chemistry , : , 2026 |
| Abstract : |
| PubMedSearch : Mastnak-Sokolov_2026_J.Med.Chem__ |
| PubMedID: |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
Databases
PDB-Sum : 30GY Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 30GY Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 30GY Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 30GY 3D, interactive encyclopedia of proteins - PROTEOPEDIA server