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Substrate Report for: Cis-stilbene-oxide

General
Type Epoxide
Chemical_Nomenclature (2R,3S)-2,3-diphenyloxirane
Canonical SMILES C1=CC=C(C=C1)C2C(O2)C3=CC=CC=C3
InChI InChI=1S/C14H12O/c1-3-7-11(8-4-1)13-14(15-13)12-9-5-2-6-10-12/h1-10,13-14H/t13-,14+
InChIKey ARCJQKUWGAZPFX-OKILXGFUSA-N
Other name(s) Cis-Stilbene oxide ; (2R,3S)-2,3-diphenyloxirane ; UNII-GIX80CN6Z7 ; 1689-71-0 ; CCRIS 2080 ; Trans-Stilbene oxide ; cSO
________________________________________________________________________________________________
MW|196.24
Formula|C14H12O
CAS_number|
PubChem|98511
UniChem|ARCJQKUWGAZPFX-OKILXGFUSA-N
IUPHAR|
Wikipedia|

Target
Families | Cis-stilbene-oxide ligand of proteins in family: CFTR-inhibitory-factor_Cif, Epoxide_hydrolase
Stucture | 1 structure: 5TNE: Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted (2R,3S)-2,3-diphenyloxirane (cis-stilbene oxide) cSO
Protein | pseae-PA2934, yeast-SCYNR064C, human-EPHX1, ratno-hyep, drome-CG15102, arath-At2g26740, mouse-EPHX1

References:
Search PubMed for references concerning: Cis-stilbene-oxide

8 more
    Title: Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase
    Hvorecny KL, Bahl CD, Kitamura S, Lee KSS, Hammock BD, Morisseau C, Madden DR
    Ref: Structure, 25:697, 2017 : PubMed

            

    Title: Development of fluorescent substrates for microsomal epoxide hydrolase and application to inhibition studies
    Morisseau C, Bernay M, Escaich A, Sanborn JR, Lango J, Hammock BD
    Ref: Analytical Biochemistry, 414:154, 2011 : PubMed

            

    Title: The Saccharomyces cerevisiae ORF YNR064c protein has characteristics of an 'orphaned' epoxide hydrolase
    Elfstrom LT, Widersten M
    Ref: Biochimica & Biophysica Acta, 1748:213, 2005 : PubMed