Local anesthetic

General

A local anesthetic (LA) is a medication that causes absence of pain sensation. In the context of surgery, a local anesthetic creates an absence of pain in a specific location of the body without a loss of consciousness, as opposed to a general anesthetic. When it is used on specific nerve pathways (local anesthetic nerve block), paralysis (loss of muscle power) also can be achieved.
Inhibitor Main targeted enzyme families Type Structure
Bucricaine ACHE Local anesthetic Derivative of Tacrine Acridine
2-Chloroprocaine BCHE Local anesthetic Not AlphaBeta Hydrolase target Organochlorine
Dibucaine BCHE Local anesthetic Quinoline Drug Not AlphaBeta Hydrolase target Carboxamide
Procainamide BCHE ACHE Local anesthetic Not AlphaBeta Hydrolase target Anti-Arrhythmia Agents Benzamide
Procaine BCHE Local anesthetic Drug Not AlphaBeta Hydrolase target
Tetracaine BCHE Local anesthetic Drug Not AlphaBeta Hydrolase target Organochlorine
Bucricaine ACHE Local anesthetic Derivative of Tacrine Acridine
2-Chloroprocaine BCHE Local anesthetic Not AlphaBeta Hydrolase target Organochlorine
Dibucaine BCHE Local anesthetic Quinoline Drug Not AlphaBeta Hydrolase target Carboxamide
Procainamide BCHE ACHE Local anesthetic Not AlphaBeta Hydrolase target Anti-Arrhythmia Agents Benzamide
Procaine BCHE Local anesthetic Drug Not AlphaBeta Hydrolase target
Tetracaine BCHE Local anesthetic Drug Not AlphaBeta Hydrolase target Organochlorine
Bucricaine ACHE Local anesthetic Derivative of Tacrine Acridine
2-Chloroprocaine BCHE Local anesthetic Not AlphaBeta Hydrolase target Organochlorine
Dibucaine BCHE Local anesthetic Quinoline Drug Not AlphaBeta Hydrolase target Carboxamide
Procainamide BCHE ACHE Local anesthetic Not AlphaBeta Hydrolase target Anti-Arrhythmia Agents Benzamide
Procaine BCHE Local anesthetic Drug Not AlphaBeta Hydrolase target
Tetracaine BCHE Local anesthetic Drug Not AlphaBeta Hydrolase target Organochlorine