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Quinoline

General

Quinoline is a heterocyclic aromatic organic compound with the chemical formula C9H7N. 1-Benzopyridine. Building block for many inhibitors of enzymes
Inhibitor Main targeted enzyme families Type Structure
NPD14805 RsbQ-like Strigolactone receptors ligand Quinoline
DC661 Palmitoyl-protein_thioesterase Quinoline
Ferulic-Acid-Piperazine-Cpd13a ACHE Multitarget Piperazin Quinoline Feruloyl Metal ion chelator anti-Abeta-aggregation Antioxidant
DJ-53 Epoxide_hydrolase Urea derivative Quinoline Trifluoro
WZU-13 Carb_B_Chordata Benzamide Carboxamide Quinoline
CHEMBL4240861 ACHE Inden Multitarget BACE1-inhibitor Quinoline
Ezurpimtrostat Palmitoyl-protein_thioesterase Piperidine Quinoline
S21-1001 BCHE Piperazine Quinoline
BuChE-IN-TM-10 BCHE Feruloyl Hydroxycinnamic-ester Multitarget Isoquinoline Monoamine-oxidase-inhibitor
CHEMBL4177075 ACHE Carbamate Quinoline
CHEMBL4177075-INDY ACHE BCHE Multitarget Benzothiazol Carbamate Quinoline
Di-tert-butyl-phenol-octylamino-cycloheptaquinolin-18d BCHE Multitarget Derivative of Tacrine Quinoline Antioxidant tert-Butyl Alkyl linked bis-ligand
(S)Aporphine-N-benzylpyridinium ACHE Isoquinoline Pyridine Alkaloid
Amiridine-Admantyl-5d BCHE Quinoline Derivative of Tacrine Derivative of Amiridine Adamantyl NMDA-Ligand Multitarget Naphthalen
Amiridine-thiouracil-13c BCHE Quinoline Derivative of Tacrine Derivative of Amiridine Pyrimidine Sulfur Compound anti-Abeta-aggregation
BR102910 DPP4N_Peptidase_S9 Quinoline Carboxamide Pyrrolidine Cyanide Sulfur Compound
UAMC-1110 DPP4N_Peptidase_S9 Quinoline Carboxamide Pyrrolidine Cyanide
IOCB22-AP446 DPP4N_Peptidase_S9 Pyrrolidine Quinoline Carboxamide
spiro-b-lactam-pyrroloquinoline-6b S9N_PPCE_Peptidase_S9 Azaspiro beta-Lactam Pyrrolidine Quinoline
O-Methyl-Dauracine DPP4N_Peptidase_S9 Alkaloid Natural Quinoline
J8-A34 ACHE Piperidine Sulfur Compound Sulfonamide Quinoline Derivative of Donepezil
Compound19n-quinolinol ACHE Trifluoro anti-Abeta-aggregation Metal ion chelator Quinoline Multitarget Derivative of Donepezil
JS0-7ZPB BCHE Quinoline Piperazine Multitarget Monoamine-oxidase-inhibitor prop-2-yn-1-yl
WMY90-5f ACHE Quinoline Multitarget Monoamine-oxidase-inhibitor Derivative of Donepezil
DPH6 BCHE ACHE Quinoline Multitarget Monoamine-oxidase-inhibitor Derivative of Donepezil
AI6-7QBR BCHE Quinoline Piperazine tert-Butyl Multitarget Monoamine-oxidase-inhibitor prop-2-yn-1-yl
AI0-7QBQ BCHE ACHE Quinoline Multitarget Monoamine-oxidase-inhibitor
Di-tert-butyl-4-Amino-2,3-cycloheptaquinoline-8c BCHE Quinoline Multitarget Antioxidant tert-Butyl
Cinchonidine BCHE Natural Alkaloid Derivative of Cinchonine Quinoline Azabicyclo
Cinchonine BCHE Natural Alkaloid Derivative of Cinchonine Quinoline Azabicyclo
CD-Bzl BCHE Alkaloid Derivative of Cinchonine Quinoline Natural_modified
Tacrine-dihydropyrimidine-4e ACHE Multitarget Derivative of Tacrine Calcium Channel Antagonist Sulfur Compound Quinoline Pyrimidine
M30D ACHE Monoamine-oxidase-inhibitor Multitarget Carbamate Quinoline
Cpd8f-quinoline-carboxamide Hormone-sensitive_lipase_like Quinoline Carboxamide
WWL153 PAF-Acetylhydrolase Piperazine Quinoline pNP
JMN4 PAF-Acetylhydrolase Piperazine Quinoline
(Isoquinolin-1-ylsulfanyl)-acetic-acid Pectinacetylesterase-Notum Fragment inhibitor of Notum Isoquinoline Quinoline Sulfur Compound
VL1-8MH Haloalkane_dehalogenase-HLD2 Fluorescent Probe HaloTag-ligand Isoquinoline Quinoline
Emetine Hydrolase_RBBP9_YdeN Natural Alkaloid Drug Isoquinoline Quinoline Quinolizine
8U2-7AIX7AY-compound5i ACHE BCHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant
8U5-7AIW-compound5g ACHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant
8UE-7AIV-compound5f ACHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant
8UQ-7AIU-compound5d ACHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant
8UK-7AIT-compound5c ACHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant
8UH-7AIS-compound5b ACHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant
SB31184-49R-4Y2U Epoxide_hydrolase Carbamate Quinoline tert-Butyloxycarbonyl tert-Butyl
beta-lactam-A295 DPP4N_Peptidase_S9 Quinoline Piperazine
4-Oxo-beta-Lactam-91-sub DPP4N_Peptidase_S9 Isoquinoline beta-Lactam Azetidin
4-Oxo-beta-Lactam-91 DPP4N_Peptidase_S9 Isoquinoline beta-Lactam
CHEMBL2152538 Not A\/B H target Isoquinoline Quinazoline Leaving group
Palmatine ACHE Natural Alkaloid Not A\/B H target Isoquinoline
Berberine ACHE BCHE Natural Alkaloid Not A\/B H target Isoquinoline Benzodioxo Antioxidant
S06-1011 BCHE Quinoline Imidazole Oxadiazol Benzimidazole
Tetracyclic-carbamate-cp8 BCHE PET probe Carbamate Natural_modified Derivative of Evodiamine Isoquinoline Quinazoline
Tetracyclic-carbamate-melatonine-3c BCHE Carbamate Natural_modified Derivative of Evodiamine Isoquinoline Quinazoline Derivative of Tryptamine Indole Alkyl linked bis-ligand
Tetracyclic-carbamate-ferulicacid-4a BCHE Carbamate Natural_modified Derivative of Evodiamine Isoquinoline Quinazoline Feruloyl Antioxidant Alkyl linked bis-ligand
Tetracyclic-carbamate-UW-MD-95 BCHE Carbamate Natural_modified Derivative of Evodiamine Isoquinoline Quinazoline
Chlorophenyl-quinolin-1,3,4-oxadiazol-thio-acetamide ACHE Sulfur Compound Quinoline Oxadiazol Carboxamide
CHEMBL4454960 BCHE Morpholine Isoquinoline Carbamate Quinazoline
ZINC20166201-cpd8 BCHE Piperazine Quinoline
8012-9656 BCHE Quinoline Imidazole Oxadiazol Benzimidazole
Isoquinoline-45-JV8 Pectinacetylesterase-Notum Isoquinoline
Tetracyclic-carbamate-photoswitch-azo BCHE Carbamate Natural_modified Derivative of Evodiamine Isoquinoline Quinazoline Photoswitch
6F7Q-cpd11 BCHE Multitarget Antioxidant Piperidine Quinoline Metal ion chelator Inden Carboxamide
Amodiaquine ACHE Quinoline Not A\/B H target Drug
FAPI-04 DPP4N_Peptidase_S9 Piperazine Quinoline PET probe Carboxamide tert-Butyl tert-Butyloxycarbonyl
CHEMBL1951424 DPP4N_Peptidase_S9 Piperidine Cyanide Quinoline Pyrrolidine
CHEMBL2058971 DPP4N_Peptidase_S9 Trifluoro Pyrrolidine Quinoline Thiazolidine Sulfur Compound
TAK-294 DPP4N_Peptidase_S9 Isoquinoline
Tetrahydroisoquinoline-derivative DPP4N_Peptidase_S9 Isoquinoline Carboxamide
Donepezil-8-Hydroxyquinoline-2b BCHE Quinoline Multitarget Antioxidant Derivative of Donepezil
ST052207 BCHE Quinoline Carbazol
CHEMBL3125351 Cholesterol_esterase Quinoline Indole
CHEMBL3125346 Cholesterol_esterase Quinoline Indole
Tacrine(8)-4-aminoquinoline ACHE Derivative of Tacrine Quinoline Alkyl linked bis-ligand
40V BCHE Piperidine Quinoline Multitarget Carboxamide Metal ion chelator Inden
T-82(1) ACHE Piperidine Quinoline
TZ2PIQA5 ACHE Acridine Quinoline Derivative of Tacrine Alkyl linked bis-ligand Triazol
FBQ ACHE Trifluoro Transition state analogue Quinoline Derivative of Tacrine Sulfur Compound
2-Methoxyhuprine ACHE Derivative of Huperzine Derivative of Tacrine Quinoline Natural_modified
Acridine ACHE Acridine Quinoline
Atracurium BCHE Not A\/B H target Neuromuscular Nondepolarizing Agents Drug Isoquinoline Propionate
Quinolinetrione-tacrine-Cpd3 ACHE Quinoline Multitarget Derivative of Tacrine Acridine Alkyl linked bis-ligand anti-Abeta-aggregation
DEPQ ACHE Organophosphate Quinoline
Dibucaine BCHE Local anesthetic Quinoline Drug Not A\/B H target Carboxamide
Naftalofos ACHE Insecticide Isoquinoline Organophosphate
Duador BCHE Pyrrolidine Neuromuscular Nondepolarizing Agents Quinoline Not A\/B H target
HuprineW ACHE Derivative of Huperzine Derivative of Tacrine Quinoline Natural_modified
HuprineX ACHE Derivative of Huperzine Derivative of Tacrine Quinoline Natural_modified
MEPQ ACHE Organophosphate Quinoline
BChE-IN-21 BCHE Pyridine Quinoline Carboxamide
Jatrorrhizine Natural Alkaloid Not A\/B H target Isoquinoline
Mivacurium BCHE Neuromuscular Nondepolarizing Agents Isoquinoline Bisquaternary Drug Not A\/B H target
N-Methyl-7-dimethylcarbamoxyquinolinium ACHE BCHE Carbamate Quinoline
N-Methyl-7-hydroxyquinolinium BCHE Quinoline
NIK-247 ACHE BCHE Quinoline Derivative of Tacrine Derivative of Amiridine
Tryptophan-tetrahydroisoquinoline-Cpd7g BCHE Quinoline Derivative of Tryptophan Isoquinoline
Bis-alkylene-Amiridine-3c BCHE Derivative of Amiridine Quinoline Alkyl linked bis-ligand
Quilostigmine ACHE Derivative of physostigmine-eserine Carbamate Isoquinoline Indole
(R)-Tacrine(10)-Hupyridone ACHE Derivative of Huperzine Derivative of Tacrine Quinoline Alkyl linked bis-ligand
(S,S)-(-)-bis(12)-hupyridone ACHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand
(S,S)-(-)-bis(10)-hupyridone ACHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand
Hupyridone ACHE Derivative of Huperzine Quinoline
Doxacurium BCHE Neuromuscular Nondepolarizing Agents Isoquinoline Bisquaternary Not A\/B H target
Cisatracurium BCHE Propionate Isoquinoline Neuromuscular Nondepolarizing Agents Nicotinic antagonist Bisquaternary Not A\/B H target