Title : CI-1017, a functionally M1-selective muscarinic agonist: design, synthesis, and preclinical pharmacology - Tecle_2000_Pharm.Acta.Helv_74_141 |
Author(s) : Tecle H , Schwarz RD , Barrett SD , Callahan MJ , Caprathe BW , Davis RE , Doyle P , Emmerling M , Lauffer DJ , Mirzadegan T , Moreland DW , Lipiniski W , Nelson C , Raby C , Spencer C , Spiegel K , Thomas AJ , Jaen JC |
Ref : Pharm Acta Helv , 74 :141 , 2000 |
Abstract : |
PubMedSearch : Tecle_2000_Pharm.Acta.Helv_74_141 |
PubMedID: 10812951 |
Title : Combining tacrine with milameline reverses a scopolamine-induced impairment of continuous performance in rhesus monkeys - Callahan_1999_Psychopharmacology.(Berl)_144_234 |
Author(s) : Callahan MJ |
Ref : Psychopharmacology (Berl) , 144 :234 , 1999 |
Abstract : |
PubMedSearch : Callahan_1999_Psychopharmacology.(Berl)_144_234 |
PubMedID: 10435389 |
Title : Milameline (CI-979\/RU35926): a muscarinic receptor agonist with cognition-activating properties: biochemical and in vivo characterization - Schwarz_1999_J.Pharmacol.Exp.Ther_291_812 |
Author(s) : Schwarz RD , Callahan MJ , Coughenour LL , Dickerson MR , Kinsora JJ , Lipinski WJ , Raby CA , Spencer CJ , Tecle H |
Ref : Journal of Pharmacology & Experimental Therapeutics , 291 :812 , 1999 |
Abstract : |
PubMedSearch : Schwarz_1999_J.Pharmacol.Exp.Ther_291_812 |
PubMedID: 10525104 |
Title : Design and synthesis of m1-selective muscarinic agonists: (R)-(-)-(Z)-1-Azabicyclo[2.2.1]heptan-3-one, O-(3-(3'-methoxyphenyl)-2-propynyl)oxime maleate (CI-1017), a functionally m1-selective muscarinic agonist - Tecle_1998_J.Med.Chem_41_2524 |
Author(s) : Tecle H , Barrett SD , Lauffer DJ , Augelli-Szafran C , Brann MR , Callahan MJ , Caprathe BW , Davis RE , Doyle PD , Eubanks D , Lipiniski W , Mirzadegan T , Moos WH , Moreland DW , Nelson CB , Pavia MR , Raby C , Schwarz RD , Spencer CJ , Thomas AJ , Jaen JC |
Ref : Journal of Medicinal Chemistry , 41 :2524 , 1998 |
Abstract : |
PubMedSearch : Tecle_1998_J.Med.Chem_41_2524 |
PubMedID: 9651157 |
Title : Poster: Pharmacological characterization of PD150714: An m1 selective muscarinic antagonist - |
Author(s) : Nelson CB , Augelli-Szafran CE , Callahan MJ , Christoffersen C , Jaen JC , Meltzer LT , Penvose JR , Schwarz RD , Thomas AJ , Wiley J |
Ref : Life Sciences , 56(11-12) :1017 , 1995 |
PubMedID: |
Title : PD 142676 (CI 1002), a novel anticholinesterase and muscarinic antagonist - Emmerling_1994_Mol.Neurobiol_9_93 |
Author(s) : Emmerling MR , Gregor VE , Schwarz RD , Scholten JD , Callahan MJ , Lee C , Moore CJ , Raby C , Lipinski WJ , Davis RE |
Ref : Molecular Neurobiology , 9 :93 , 1994 |
Abstract : |
PubMedSearch : Emmerling_1994_Mol.Neurobiol_9_93 |
PubMedID: 7888109 |
Title : Subtype selective muscarinic agonists: potential therapeutic agents for Alzheimer's disease - |
Author(s) : Davis RD , Raby C , Callahan MJ , Lipinski W , Schwarz RD , Dudley DT , Lauffer DJ , Reece P , Jaen JC , Tecle H |
Ref : Prog Brain Res , 98 :439 , 1993 |
PubMedID: 8248534 |