Thomas AJ

References (13)

Title : In vivo nucleus basalis of Meynert degeneration in mild cognitive impairment with Lewy bodies - Schumacher_2021_Neuroimage.Clin_30_102604
Author(s) : Schumacher J , Taylor JP , Hamilton CA , Firbank M , Cromarty RA , Donaghy PC , Roberts G , Allan L , Lloyd J , Durcan R , Barnett N , O'Brien JT , Thomas AJ
Ref : Neuroimage Clin , 30 :102604 , 2021
Abstract :
PubMedSearch : Schumacher_2021_Neuroimage.Clin_30_102604
PubMedID: 33711623

Title : A comparison of the efficacy of donepezil in Parkinson's disease with dementia and dementia with Lewy bodies - Thomas_2005_Int.J.Geriatr.Psychiatry_20_938
Author(s) : Thomas AJ , Burn DJ , Rowan EN , Littlewood E , Newby J , Cousins D , Pakrasi S , Richardson J , Sanders J , McKeith IG
Ref : Int J Geriatr Psychiatry , 20 :938 , 2005
Abstract :
PubMedSearch : Thomas_2005_Int.J.Geriatr.Psychiatry_20_938
PubMedID: 16163744

Title : CI-1017, a functionally M1-selective muscarinic agonist: design, synthesis, and preclinical pharmacology - Tecle_2000_Pharm.Acta.Helv_74_141
Author(s) : Tecle H , Schwarz RD , Barrett SD , Callahan MJ , Caprathe BW , Davis RE , Doyle P , Emmerling M , Lauffer DJ , Mirzadegan T , Moreland DW , Lipiniski W , Nelson C , Raby C , Spencer C , Spiegel K , Thomas AJ , Jaen JC
Ref : Pharm Acta Helv , 74 :141 , 2000
Abstract :
PubMedSearch : Tecle_2000_Pharm.Acta.Helv_74_141
PubMedID: 10812951

Title : Identification and characterization of m1 selective muscarinic receptor antagonists1 - Augelli-Szafran_1999_J.Med.Chem_42_356
Author(s) : Augelli-Szafran CE , Blankley CJ , Jaen JC , Moreland DW , Nelson CB , Penvose-Yi JR , Schwarz RD , Thomas AJ
Ref : Journal of Medicinal Chemistry , 42 :356 , 1999
Abstract :
PubMedSearch : Augelli-Szafran_1999_J.Med.Chem_42_356
PubMedID: 9986705

Title : Design and synthesis of m1-selective muscarinic agonists: (R)-(-)-(Z)-1-Azabicyclo[2.2.1]heptan-3-one, O-(3-(3'-methoxyphenyl)-2-propynyl)oxime maleate (CI-1017), a functionally m1-selective muscarinic agonist - Tecle_1998_J.Med.Chem_41_2524
Author(s) : Tecle H , Barrett SD , Lauffer DJ , Augelli-Szafran C , Brann MR , Callahan MJ , Caprathe BW , Davis RE , Doyle PD , Eubanks D , Lipiniski W , Mirzadegan T , Moos WH , Moreland DW , Nelson CB , Pavia MR , Raby C , Schwarz RD , Spencer CJ , Thomas AJ , Jaen JC
Ref : Journal of Medicinal Chemistry , 41 :2524 , 1998
Abstract :
PubMedSearch : Tecle_1998_J.Med.Chem_41_2524
PubMedID: 9651157

Title : Poster: Aryleneyne 1-azabicyclo[2.2.1]heptan-3-one oximes: Potent muscarinic agonists -
Author(s) : Tecle H , Lauffer DJ , Davis RE , Mirzadegan T , Moreland DW , Schwarz RD , Thomas AJ , Raby C , Jaen JC
Ref : Life Sciences , 56(11-12) :1003 , 1995
PubMedID:

Title : Poster: Identification and characterization of m1 selective muscarinic antagonists -
Author(s) : Augelli-Szafran CE , Blankley CJ , Jaen JC , Moreland DW , Nelson CB , Penvose JR , Schwarz RD , Thomas AJ
Ref : Life Sciences , 56(11-12) :1017 , 1995
PubMedID:

Title : Poster: Pharmacological characterization of PD150714: An m1 selective muscarinic antagonist -
Author(s) : Nelson CB , Augelli-Szafran CE , Callahan MJ , Christoffersen C , Jaen JC , Meltzer LT , Penvose JR , Schwarz RD , Thomas AJ , Wiley J
Ref : Life Sciences , 56(11-12) :1017 , 1995
PubMedID:

Title : Poster: Effect of mutating aspart ate 103 to glutamate or asparagine in the Hm2 subtype on binding of agonists and antagonists of varied pKa and subtype selectivity -
Author(s) : Spencer CJ , Schwarz RD , Moreland DW , Thomas AJ , Tecle H
Ref : Life Sciences , 56(11-12) :1020 , 1995
PubMedID:

Title : Mutations of aspartate 103 in the Hm2 receptor and alterations in receptor binding properties of muscarinic agonists - Schwarz_1995_Life.Sci_56(11-12)_923
Author(s) : Schwarz RD , Spencer CJ , Jaen JC , Mirzadegan T , Moreland DW , Tecle H , Thomas AJ
Ref : Life Sciences , 56(11-12) :923 , 1995
Abstract :
PubMedSearch : Schwarz_1995_Life.Sci_56(11-12)_923
PubMedID: 10188794

Title : Characterization of muscarinic agonists in recombinant cell lines - Schwarz_1993_Life.Sci_52(5-6)_465
Author(s) : Schwarz RD , Davis RE , Jaen JC , Spencer CJ , Tecle H , Thomas AJ
Ref : Life Sciences , 52 :465 , 1993
Abstract :
PubMedSearch : Schwarz_1993_Life.Sci_52(5-6)_465
PubMedID: 8382764

Title : Cholinergic agents: effect of methyl substitution in a series of arecoline derivatives on binding to muscarinic acetylcholine receptors - Moos_1992_J.Pharm.Sci_81_1015
Author(s) : Moos WH , Bergmeier SC , Coughenour LL , Davis RE , Hershenson FM , Kester JA , McKee JS , Marriott JG , Schwarz RD , Tecle H , Thomas AJ
Ref : J Pharm Sci , 81 :1015 , 1992
Abstract :
PubMedSearch : Moos_1992_J.Pharm.Sci_81_1015
PubMedID: 1432612

Title : Poster: Inhibition of rat acetyl- and butyrylcholinesterase activity by tacrine and related aminoacridines -
Author(s) : Schwarz RD , Spencer CJ , Davis RE , Moos WH , Pavia MR , Thomas AJ
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :343 , 1991
PubMedID: