Mirzadegan T

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Full name : Mirzadegan Tara

First name : Tara

Mail : Computer-aided Drug Design, Janssen Research & Development, LLC, San Diego, California 9212

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Country : USA

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References (8)

Title : Sequence analyses of G-protein-coupled receptors: similarities to rhodopsin -
Author(s) : Mirzadegan T , Benko G , Filipek S , Palczewski K
Ref : Biochemistry , 42 :2759 , 2003
PubMedID: 12627940

Title : CI-1017, a functionally M1-selective muscarinic agonist: design, synthesis, and preclinical pharmacology - Tecle_2000_Pharm.Acta.Helv_74_141
Author(s) : Tecle H , Schwarz RD , Barrett SD , Callahan MJ , Caprathe BW , Davis RE , Doyle P , Emmerling M , Lauffer DJ , Mirzadegan T , Moreland DW , Lipiniski W , Nelson C , Raby C , Spencer C , Spiegel K , Thomas AJ , Jaen JC
Ref : Pharm Acta Helv , 74 :141 , 2000
Abstract :
PubMedSearch : Tecle_2000_Pharm.Acta.Helv_74_141
PubMedID: 10812951

Title : Design and synthesis of m1-selective muscarinic agonists: (R)-(-)-(Z)-1-Azabicyclo[2.2.1]heptan-3-one, O-(3-(3'-methoxyphenyl)-2-propynyl)oxime maleate (CI-1017), a functionally m1-selective muscarinic agonist - Tecle_1998_J.Med.Chem_41_2524
Author(s) : Tecle H , Barrett SD , Lauffer DJ , Augelli-Szafran C , Brann MR , Callahan MJ , Caprathe BW , Davis RE , Doyle PD , Eubanks D , Lipiniski W , Mirzadegan T , Moos WH , Moreland DW , Nelson CB , Pavia MR , Raby C , Schwarz RD , Spencer CJ , Thomas AJ , Jaen JC
Ref : Journal of Medicinal Chemistry , 41 :2524 , 1998
Abstract :
PubMedSearch : Tecle_1998_J.Med.Chem_41_2524
PubMedID: 9651157

Title : Mutations of aspartate 103 in the Hm2 receptor and alterations in receptor binding properties of muscarinic agonists - Schwarz_1995_Life.Sci_56(11-12)_923
Author(s) : Schwarz RD , Spencer CJ , Jaen JC , Mirzadegan T , Moreland DW , Tecle H , Thomas AJ
Ref : Life Sciences , 56(11-12) :923 , 1995
Abstract :
PubMedSearch : Schwarz_1995_Life.Sci_56(11-12)_923
PubMedID: 10188794

Title : Poster: Aryleneyne 1-azabicyclo[2.2.1]heptan-3-one oximes: Potent muscarinic agonists -
Author(s) : Tecle H , Lauffer DJ , Davis RE , Mirzadegan T , Moreland DW , Schwarz RD , Thomas AJ , Raby C , Jaen JC
Ref : Life Sciences , 56(11-12) :1003 , 1995
PubMedID:

Title : Synthesis and SAR of bulky 1-azabicyclo[2.2.1]-3-one oximes as muscarinic receptor subtype selective agonists - Tecle_1993_Life.Sci_52(5-6)_505
Author(s) : Tecle H , Lauffer DJ , Mirzadegan T , Moos WH , Moreland DW , Pavia MR , Schwarz RD , Davis RE
Ref : Life Sciences , 52 :505 , 1993
Abstract :
PubMedSearch : Tecle_1993_Life.Sci_52(5-6)_505
PubMedID: 8382765

Title : Poster: Molecular modeling studies of the m1 and m2 muscarinic receptors leading to the design of selective m1 agonists -
Author(s) : Mirzadegan T , Tecle H , Lauffer DJ , Humblet C
Ref : Life Sciences , 52(5-6) :561 , 1993
PubMedID:

Title : Modeling rhodopsin, a member of G-protein coupled receptors, by computer graphics. Interpretation of chemical shifts of fluorinated rhodopsins - Mirzadegan_1992_Photochem.Photobiol_56_883
Author(s) : Mirzadegan T , Humblet C , Ripka WC , Colmenares LU , Liu RS
Ref : Photochem Photobiol , 56 :883 , 1992
Abstract :
PubMedSearch : Mirzadegan_1992_Photochem.Photobiol_56_883
PubMedID: 1492134