Full name : Spencer Carol J
First name : Carol J
Mail : Parke-Davis Pharmaceutical Research, Division of Warner Lambert Company, Ann Arbor, Michigan
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Country : USA
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Comment
| Title : Milameline (CI-979\/RU35926): a muscarinic receptor agonist with cognition-activating properties: biochemical and in vivo characterization - Schwarz_1999_J.Pharmacol.Exp.Ther_291_812 |
| Author(s) : Schwarz RD , Callahan MJ , Coughenour LL , Dickerson MR , Kinsora JJ , Lipinski WJ , Raby CA , Spencer CJ , Tecle H |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 291 :812 , 1999 |
| Abstract : |
| PubMedSearch : Schwarz_1999_J.Pharmacol.Exp.Ther_291_812 |
| PubMedID: 10525104 |
| Title : Design and synthesis of m1-selective muscarinic agonists: (R)-(-)-(Z)-1-Azabicyclo[2.2.1]heptan-3-one, O-(3-(3'-methoxyphenyl)-2-propynyl)oxime maleate (CI-1017), a functionally m1-selective muscarinic agonist - Tecle_1998_J.Med.Chem_41_2524 |
| Author(s) : Tecle H , Barrett SD , Lauffer DJ , Augelli-Szafran C , Brann MR , Callahan MJ , Caprathe BW , Davis RE , Doyle PD , Eubanks D , Lipiniski W , Mirzadegan T , Moos WH , Moreland DW , Nelson CB , Pavia MR , Raby C , Schwarz RD , Spencer CJ , Thomas AJ , Jaen JC |
| Ref : Journal of Medicinal Chemistry , 41 :2524 , 1998 |
| Abstract : |
| PubMedSearch : Tecle_1998_J.Med.Chem_41_2524 |
| PubMedID: 9651157 |
| Title : In vitro and in vivo evaluation of the subtype-selective muscarinic agonist PD 151832 - Jaen_1995_Life.Sci_56(11-12)_845 |
| Author(s) : Jaen JC , Barrett S , Brann M , Callahan M , Davis R , Doyle P , Eubanks D , Lauffer DJ , Lauffer L , Lipinski W , Moreland DW , Nelson C , Raby C , Schwarz RD , Spencer CJ , Tecle H |
| Ref : Life Sciences , 56(11-12) :845 , 1995 |
| Abstract : |
| PubMedSearch : Jaen_1995_Life.Sci_56(11-12)_845 |
| PubMedID: 10188784 |
| Title : Mutations of aspartate 103 in the Hm2 receptor and alterations in receptor binding properties of muscarinic agonists - Schwarz_1995_Life.Sci_56(11-12)_923 |
| Author(s) : Schwarz RD , Spencer CJ , Jaen JC , Mirzadegan T , Moreland DW , Tecle H , Thomas AJ |
| Ref : Life Sciences , 56(11-12) :923 , 1995 |
| Abstract : |
| PubMedSearch : Schwarz_1995_Life.Sci_56(11-12)_923 |
| PubMedID: 10188794 |
| Title : Poster: Effect of mutating aspart ate 103 to glutamate or asparagine in the Hm2 subtype on binding of agonists and antagonists of varied pKa and subtype selectivity - |
| Author(s) : Spencer CJ , Schwarz RD , Moreland DW , Thomas AJ , Tecle H |
| Ref : Life Sciences , 56(11-12) :1020 , 1995 |
| PubMedID: |
| Title : Poster: Mutations of aspartate 103 in human muscarinic receptor subtype m2 expressed in cos-7 cells: Effects on receptor binding and signal transduction - |
| Author(s) : Spencer CJ , Schwarz RD , Lauffer L |
| Ref : Life Sciences , 52(5-6) :562 , 1993 |
| PubMedID: |
| Title : Characterization of muscarinic agonists in recombinant cell lines - Schwarz_1993_Life.Sci_52(5-6)_465 |
| Author(s) : Schwarz RD , Davis RE , Jaen JC , Spencer CJ , Tecle H , Thomas AJ |
| Ref : Life Sciences , 52 :465 , 1993 |
| Abstract : |
| PubMedSearch : Schwarz_1993_Life.Sci_52(5-6)_465 |
| PubMedID: 8382764 |
| Title : Poster: Comparisons between human muscarinic receptor subtypes coupled to phospholipase C and those coupled to adenylyl cyclase: Effect of receptor reserve - |
| Author(s) : Lauffer L , Schwarz RD , Spencer CJ |
| Ref : Life Sciences , 52(5-6) :563 , 1993 |
| PubMedID: |
| Title : Poster: Inhibition of rat acetyl- and butyrylcholinesterase activity by tacrine and related aminoacridines - |
| Author(s) : Schwarz RD , Spencer CJ , Davis RE , Moos WH , Pavia MR , Thomas AJ |
| Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :343 , 1991 |
| PubMedID: |
| Title : Poster: Muscarinic receptor binding, phosphatidylinositol (PI) turnover and Ca2+ mobilization in cells transformed to selectiveIy express rat m1 muscarinic receptors - |
| Author(s) : Schwarz RD , Coughenour LL , Dudley DT , Boyd DK , Fergus JH , Myers SL , Spencer CJ , Clark CR |
| Ref : Trends in Pharmacological Sciences , Suppl :116 , 1989 |
| PubMedID: |
| Title : Control of the Release of [3H]-Acetylcholine from Rat Hippocampal Slices by Aminopyridines and Phencyclidine - |
| Author(s) : Schwarz RD , Spencer CJ , Bernabei AA , Pugsley TA |
| Ref : Advances in Behavioral Biology , 30 :653 , 1986 |
| PubMedID: |