Title : Enhancing Drug Discovery and Development through the Integration of Medicinal Chemistry, Chemical Biology, and Academia-Industry Partnerships: Insights from Roche's Endocannabinoid System Projects - Aebi_2024_Chimia.(Aarau)_78_499 |
Author(s) : Aebi J , Atz K , Ametamey SM , Benz J , Blaising J , Butini S , Campiani G , Carreira EM , Collin L , De Lago E , Gazzi T , Gertsch J , Gobbi L , Guba W , Fernandez-Ruiz J , Fingerle J , Haider A , He Y , Heitman LH , Honer M , Hunziker D , Kuhn B , Maccarrone M , Marki HP , Martin RE , Mohr P , Mu L , Nazare M , Nippa DF , Oddi S , O'Hara F , Pacher P , Romero J , Rover S , Rufer AC , Schibli R , Schneider G , Stepan AF , Sykes DA , Ullmer C , van der Stelt M , Veprintsev DB , Wittwer MB , Grether U |
Ref : Chimia (Aarau) , 78 :499 , 2024 |
Abstract : |
PubMedSearch : Aebi_2024_Chimia.(Aarau)_78_499 |
PubMedID: 39221845 |
Title : Aryl- and heteroaryl-substituted aminobenzo[a]quinolizines as dipeptidyl peptidase IV inhibitors - Boehringer_2010_Bioorg.Med.Chem.Lett_20_1106 |
Author(s) : Boehringer M , Fischer H , Hennig M , Hunziker D , Huwyler J , Kuhn B , Loeffler BM , Luebbers T , Mattei P , Narquizian R , Sebokova E , Sprecher U , Wessel HP |
Ref : Bioorganic & Medicinal Chemistry Lett , 20 :1106 , 2010 |
Abstract : |
PubMedSearch : Boehringer_2010_Bioorg.Med.Chem.Lett_20_1106 |
PubMedID: 20031408 |
Gene_locus related to this paper: human-DPP4 |
Title : 1,3-disubstituted 4-aminopiperidines as useful tools in the optimization of the 2-aminobenzo[a]quinolizine dipeptidyl peptidase IV inhibitors - Lubbers_2007_Bioorg.Med.Chem.Lett_17_2966 |
Author(s) : Lubbers T , Bohringer M , Gobbi L , Hennig M , Hunziker D , Kuhn B , Loffler B , Mattei P , Narquizian R , Peters JU , Ruff Y , Wessel HP , Wyss P |
Ref : Bioorganic & Medicinal Chemistry Lett , 17 :2966 , 2007 |
Abstract : |
PubMedSearch : Lubbers_2007_Bioorg.Med.Chem.Lett_17_2966 |
PubMedID: 17418568 |
Gene_locus related to this paper: human-DPP4 |
Title : Inhibitors of dipeptidyl peptidase IV--recent advances and structural views - Hunziker_2005_Curr.Top.Med.Chem_5_1623 |
Author(s) : Hunziker D , Hennig M , Peters JU |
Ref : Curr Top Med Chem , 5 :1623 , 2005 |
Abstract : |
PubMedSearch : Hunziker_2005_Curr.Top.Med.Chem_5_1623 |
PubMedID: 16375746 |
Title : An aminomethylpyrimidine DPP-IV inhibitor with improved properties - Peters_2004_Bioorg.Med.Chem.Lett_14_3575 |
Author(s) : Peters JU , Hunziker D , Fischer H , Kansy M , Weber S , Kritter S , Muller A , Wallier A , Ricklin F , Boehringer M , Poli SM , Csato M , Loeffler BM |
Ref : Bioorganic & Medicinal Chemistry Lett , 14 :3575 , 2004 |
Abstract : |
PubMedSearch : Peters_2004_Bioorg.Med.Chem.Lett_14_3575 |
PubMedID: 15177477 |