ESTHER database
Classes
Author
Block
Chemical
Disease
Enzyme
Family
Genes Locus
Inhibitor
Interact Gene Locus
Mutation
Paper
Reactivator
Species
Structure
Substrate
Type inhibitor
Type reactivator
Type substrate
Families
Overall table
All figures of families
Tools
HMMER
BLAST
Basics on AChE
Kinetics notes
Gene Structures
Molecular forms
AChE Family
Human ACHE
ESTHER Definition
Definition
Definition biblio
What is up?
Meeting
Supplementary data
Latest Modifications
Bibliography (all years)
Acknowledgements and disclaimer
Home
Author
Podkowa A
Podkowa A
References (2)
1. The Magic of Crystal Structure-Based Inhibitor Optimization: Development of a Butyrylcholinesterase Inhibitor with Picomolar Affinity and in Vivo Activity - Kosak_2018_J.Med.Chem_61_119
Title :
The Magic of Crystal Structure-Based Inhibitor Optimization: Development of a Butyrylcholinesterase Inhibitor with Picomolar Affinity and in Vivo Activity -
Kosak_2018_J.Med.Chem_61_119
Author(s) :
Kosak U
,
Brus B
,
Knez D
,
Zakelj S
,
Trontelj J
,
Pislar A
,
Sink R
,
Jukic M
,
Zivin M
,
Podkowa A
,
Nachon F
,
Brazzolotto X
,
Stojan J
,
Kos J
,
Coquelle N
,
Salat K
,
Colletier JP
,
Gobec S
Ref :
Journal of Medicinal Chemistry ,
61
:119 , 2018
Abstract :
View Abstract
PubMedSearch :
Kosak_2018_J.Med.Chem_61_119
PubMedID
:
29227101
Gene_locus related to this paper:
human-BCHE
2. Development of an in-vivo active reversible butyrylcholinesterase inhibitor - Kosak_2016_Sci.Rep_6_39495
Title :
Development of an in-vivo active reversible butyrylcholinesterase inhibitor -
Kosak_2016_Sci.Rep_6_39495
Author(s) :
Kosak U
,
Brus B
,
Knez D
,
Sink R
,
Zakelj S
,
Trontelj J
,
Pislar A
,
Slenc J
,
Gobec M
,
Zivin M
,
Tratnjek L
,
Perse M
,
Salat K
,
Podkowa A
,
Filipek B
,
Nachon F
,
Brazzolotto X
,
Wieckowska A
,
Malawska B
,
Stojan J
,
Rascan IM
,
Kos J
,
Coquelle N
,
Colletier JP
,
Gobec S
Ref :
Sci Rep ,
6
:39495 , 2016
Abstract :
View Abstract
PubMedSearch :
Kosak_2016_Sci.Rep_6_39495
PubMedID
:
28000737
Gene_locus related to this paper:
human-BCHE