Title : Chemical Proteomics Reveals Antibiotic Targets of Oxadiazolones in MRSA - Bakker_2023_J.Am.Chem.Soc_145_1136 |
Author(s) : Bakker AT , Kotsogianni I , Mirenda L , Straub VM , Avalos M , van den Berg R , Florea BI , van Wezel GP , Janssen APA , Martin NI , van der Stelt M |
Ref : Journal of the American Chemical Society , 145 :1136 , 2023 |
Abstract : |
PubMedSearch : Bakker_2023_J.Am.Chem.Soc_145_1136 |
PubMedID: 36584241 |
Gene_locus related to this paper: staa3-q2fkj0 , staau-MW0741 , staau-MW2456 , staau-SA1143 , staau-SA2367 , staau-SAV0321 , staau-SAV0655 |
Title : A monoacylglycerol lipase inhibitor showing therapeutic efficacy in mice without central side effects or dependence - Jiang_2023_Nat.Commun_14_8039 |
Author(s) : Jiang M , Huizenga MCW , Wirt JL , Paloczi J , Amedi A , van den Berg R , Benz J , Collin L , Deng H , Di X , Driever WF , Florea BI , Grether U , Janssen APA , Hankemeier T , Heitman LH , Lam TW , Mohr F , Pavlovic A , Ruf I , van den Hurk H , Stevens AF , van der Vliet D , van der Wel T , Wittwer MB , van Boeckel CAA , Pacher P , Hohmann AG , van der Stelt M |
Ref : Nat Commun , 14 :8039 , 2023 |
Abstract : |
PubMedSearch : Jiang_2023_Nat.Commun_14_8039 |
PubMedID: 38052772 |
Title : ABHD2 Inhibitor Identified by Activity-Based Protein Profiling Reduces Acrosome Reaction - Baggelaar_2019_ACS.Chem.Biol_14_2295 |
Author(s) : Baggelaar MP , den Dulk H , Florea BI , Fazio D , Perruzza D , Bernabo N , Raspa M , Janssen APA , Scavizzi F , Barboni B , Overkleeft HS , Maccarrone M , van der Stelt M |
Ref : ACS Chemical Biology , 14 :2295 , 2019 |
Abstract : |
PubMedSearch : Baggelaar_2019_ACS.Chem.Biol_14_2295 |
PubMedID: 31525885 |
Gene_locus related to this paper: human-ABHD2 , human-ABHD3 |
Title : Identification of alpha,beta-Hydrolase Domain Containing Protein 6 as a Diacylglycerol Lipase in Neuro-2a Cells - van Esbroeck_2019_Front.Mol.Neurosci_12_286 |
Author(s) : van Esbroeck ACM , Kantae V , Di X , van der Wel T , den Dulk H , Stevens AF , Singh S , Bakker AT , Florea BI , Stella N , Overkleeft HS , Hankemeier T , van der Stelt M |
Ref : Front Mol Neurosci , 12 :286 , 2019 |
Abstract : |
PubMedSearch : van Esbroeck_2019_Front.Mol.Neurosci_12_286 |
PubMedID: 31849602 |
Gene_locus related to this paper: human-ABHD6 |
Title : Activity-Based Protein Profiling Identifies alpha-Ketoamides as Inhibitors for Phospholipase A2 Group XVI - Zhou_2019_ACS.Chem.Biol_14_164 |
Author(s) : Zhou J , Mock ED , Martella A , Kantae V , Di X , Burggraaff L , Baggelaar MP , Al-Ayed K , Bakker A , Florea BI , Grimm SH , den Dulk H , Li CT , Mulder L , Overkleeft HS , Hankemeier T , van Westen GJP , van der Stelt M |
Ref : ACS Chemical Biology , 14 :164 , 2019 |
Abstract : |
PubMedSearch : Zhou_2019_ACS.Chem.Biol_14_164 |
PubMedID: 30620559 |
Title : Chemical Proteomic Analysis of Serine Hydrolase Activity in Niemann-Pick Type C Mouse Brain - van Rooden_2018_Front.Neurosci_12_440 |
Author(s) : van Rooden EJ , van Esbroeck ACM , Baggelaar MP , Deng H , Florea BI , Marques ARA , Ottenhoff R , Boot RG , Overkleeft HS , Aerts J , van der Stelt M |
Ref : Front Neurosci , 12 :440 , 2018 |
Abstract : |
PubMedSearch : van Rooden_2018_Front.Neurosci_12_440 |
PubMedID: 30018533 |
Title : Mapping in vivo target interaction profiles of covalent inhibitors using chemical proteomics with label-free quantification - van Rooden_2018_Nat.Protoc_13_752 |
Author(s) : van Rooden EJ , Florea BI , Deng H , Baggelaar MP , van Esbroeck ACM , Zhou J , Overkleeft HS , van der Stelt M |
Ref : Nat Protoc , 13 :752 , 2018 |
Abstract : |
PubMedSearch : van Rooden_2018_Nat.Protoc_13_752 |
PubMedID: 29565900 |
Title : Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474 - van Esbroeck_2017_Science_356_1084 |
Author(s) : van Esbroeck ACM , Janssen APA , Cognetta AB, 3rd , Ogasawara D , Shpak G , van der Kroeg M , Kantae V , Baggelaar MP , de Vrij FMS , Deng H , Allara M , Fezza F , Lin Z , van der Wel T , Soethoudt M , Mock ED , den Dulk H , Baak IL , Florea BI , Hendriks G , De Petrocellis L , Overkleeft HS , Hankemeier T , De Zeeuw CI , Di Marzo V , Maccarrone M , Cravatt BF , Kushner SA , van der Stelt M |
Ref : Science , 356 :1084 , 2017 |
Abstract : |
PubMedSearch : van Esbroeck_2017_Science_356_1084 |
PubMedID: 28596366 |
Title : Chemical Proteomics Maps Brain Region Specific Activity of Endocannabinoid Hydrolases - Baggelaar_2017_ACS.Chem.Biol_12_852 |
Author(s) : Baggelaar MP , van Esbroeck AC , van Rooden EJ , Florea BI , Overkleeft HS , Marsicano G , Chaouloff F , van der Stelt M |
Ref : ACS Chemical Biology , 12 :852 , 2017 |
Abstract : |
PubMedSearch : Baggelaar_2017_ACS.Chem.Biol_12_852 |
PubMedID: 28106377 |
Gene_locus related to this paper: human-ABHD4 , human-ABHD6 , human-ABHD12 , human-DAGLA , human-MGLL |
Title : Highly Selective, Reversible Inhibitor Identified by Comparative Chemoproteomics Modulates Diacylglycerol Lipase Activity in Neurons - Baggelaar_2015_J.Am.Chem.Soc_137_8851 |
Author(s) : Baggelaar MP , Chameau PJ , Kantae V , Hummel J , Hsu KL , Janssen F , van der Wel T , Soethoudt M , Deng H , den Dulk H , Allara M , Florea BI , Di Marzo V , Wadman WJ , Kruse CG , Overkleeft HS , Hankemeier T , Werkman TR , Cravatt BF , van der Stelt M |
Ref : Journal of the American Chemical Society , 137 :8851 , 2015 |
Abstract : |
PubMedSearch : Baggelaar_2015_J.Am.Chem.Soc_137_8851 |
PubMedID: 26083464 |
Gene_locus related to this paper: human-DAGLA , human-DAGLB |
Title : Development of an activity-based probe and in silico design reveal highly selective inhibitors for diacylglycerol lipase-alpha in brain - |
Author(s) : Baggelaar MP , Janssen FJ , van Esbroeck AC , den Dulk H , Allara M , Hoogendoorn S , McGuire R , Florea BI , Meeuwenoord N , van den Elst H , van der Marel GA , Brouwer J , Di Marzo V , Overkleeft HS , van der Stelt M |
Ref : Angew Chem Int Ed Engl , 52 :12081 , 2013 |
PubMedID: 24173880 |
Gene_locus related to this paper: human-DAGLA |