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Title: Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolutionHillier LW , Miller W , Birney E , Warren W , Hardison RC , Ponting CP , Bork P , Burt DW , Groenen MA and Wilson RK <164 more author(s)> Hillier LW , Miller W , Birney E , Warren W , Hardison RC , Ponting CP , Bork P , Burt DW , Groenen MA , Delany ME , Dodgson JB , Chinwalla AT , Cliften PF , Clifton SW , Delehaunty KD , Fronick C , Fulton RS , Graves TA , Kremitzki C , Layman D , Magrini V , McPherson JD , Miner TL , Minx P , Nash WE , Nhan MN , Nelson JO , Oddy LG , Pohl CS , Randall-Maher J , Smith SM , Wallis JW , Yang SP , Romanov MN , Rondelli CM , Paton B , Smith J , Morrice D , Daniels L , Tempest HG , Robertson L , Masabanda JS , Griffin DK , Vignal A , Fillon V , Jacobbson L , Kerje S , Andersson L , Crooijmans RP , Aerts J , van der Poel JJ , Ellegren H , Caldwell RB , Hubbard SJ , Grafham DV , Kierzek AM , McLaren SR , Overton IM , Arakawa H , Beattie KJ , Bezzubov Y , Boardman PE , Bonfield JK , Croning MD , Davies RM , Francis MD , Humphray SJ , Scott CE , Taylor RG , Tickle C , Brown WR , Rogers J , Buerstedde JM , Wilson SA , Stubbs L , Ovcharenko I , Gordon L , Lucas S , Miller MM , Inoko H , Shiina T , Kaufman J , Salomonsen J , Skjoedt K , Ka-Shu Wong G , Wang J , Liu B , Yu J , Yang H , Nefedov M , Koriabine M , deJong PJ , Goodstadt L , Webber C , Dickens NJ , Letunic I , Suyama M , Torrents D , von Mering C , Zdobnov EM , Makova K , Nekrutenko A , Elnitski L , Eswara P , King DC , Yang S , Tyekucheva S , Radakrishnan A , Harris RS , Chiaromonte F , Taylor J , He J , Rijnkels M , Griffiths-Jones S , Ureta-Vidal A , Hoffman MM , Severin J , Searle SM , Law AS , Speed D , Waddington D , Cheng Z , Tuzun E , Eichler E , Bao Z , Flicek P , Shteynberg DD , Brent MR , Bye JM , Huckle EJ , Chatterji S , Dewey C , Pachter L , Kouranov A , Mourelatos Z , Hatzigeorgiou AG , Paterson AH , Ivarie R , Brandstrom M , Axelsson E , Backstrom N , Berlin S , Webster MT , Pourquie O , Reymond A , Ucla C , Antonarakis SE , Long M , Emerson JJ , Betran E , Dupanloup I , Kaessmann H , Hinrichs AS , Bejerano G , Furey TS , Harte RA , Raney B , Siepel A , Kent WJ , Haussler D , Eyras E , Castelo R , Abril JF , Castellano S , Camara F , Parra G , Guigo R , Bourque G , Tesler G , Pevzner PA , Smit A , Fulton LA , Mardis ER , Wilson RK (- 164) Ref: Nature, 432 :695, 2004 : PubMed Abstract ESTHER: Hillier_2004_Nature_432_695 PubMedSearch: Hillier 2004 Nature 432 695 PubMedID: 15592404 Gene_locus related to this paper: chick-a0a1d5pmd9 ,
chick-b3tzb3 ,
chick-BCHE ,
chick-cb043 ,
chick-d3wgl5 ,
chick-e1bsm0 ,
chick-e1bvq6 ,
chick-e1bwz0 ,
chick-e1bwz1 ,
chick-e1byn1 ,
chick-e1bz81 ,
chick-e1c0z8 ,
chick-e1c7p7 ,
chick-f1nby4 ,
chick-f1ncz8 ,
chick-f1ndp3 ,
chick-f1nep4 ,
chick-f1nj68 ,
chick-f1njg6 ,
chick-f1njk4 ,
chick-f1njs4 ,
chick-f1njs5 ,
chick-f1nk87 ,
chick-f1nmx9 ,
chick-f1ntp8 ,
chick-f1nvg7 ,
chick-f1nwf2 ,
chick-f1p1l1 ,
chick-f1p3j5 ,
chick-f1p4c6 ,
chick-f1p508 ,
chick-fas ,
chick-h9l0k6 ,
chick-nlgn1 ,
chick-NLGN3 ,
chick-q5f3h8 ,
chick-q5zhm0 ,
chick-q5zi81 ,
chick-q5zij5 ,
chick-q5zin0 ,
chick-thyro ,
chick-f1nrq2 ,
chick-e1byd4 ,
chick-e1c2h6 ,
chick-a0a1d5pk92 ,
chick-a0a1d5pzg7 ,
chick-f1nbc2 ,
chick-f1nf25 ,
chick-f1nly5 ,
chick-f1p4h5 ,
chick-f1nzi7 ,
chick-f1p5k3 ,
chick-f1nm35 ,
chick-a0a1d5pl11 ,
chick-a0a1d5pj73 ,
chick-f1nxu6 ,
chick-a0a1d5nwc0 ,
chick-e1bxs8 ,
chick-f1p2g7 ,
chick-f1nd96 Abstract
We present here a draft genome sequence of the red jungle fowl, Gallus gallus. Because the chicken is a modern descendant of the dinosaurs and the first non-mammalian amniote to have its genome sequenced, the draft sequence of its genome--composed of approximately one billion base pairs of sequence and an estimated 20,000-23,000 genes--provides a new perspective on vertebrate genome evolution, while also improving the annotation of mammalian genomes. For example, the evolutionary distance between chicken and human provides high specificity in detecting functional elements, both non-coding and coding. Notably, many conserved non-coding sequences are far from genes and cannot be assigned to defined functional classes. In coding regions the evolutionary dynamics of protein domains and orthologous groups illustrate processes that distinguish the lineages leading to birds and mammals. The distinctive properties of avian microchromosomes, together with the inferred patterns of conserved synteny, provide additional insights into vertebrate chromosome architecture.
