Toelzer et al. showed that MekB (9psed-q0mrg5) from Pseudomonas veronii and CgHle (corgl-CGL0839) from Corynebacteriumglutamicum are esterases that hydrolyse preferentially acetic acid esters. MekB and CgHle cannot bind homoserine and acetyl-CoA. Accordingly a novel esterase subfamily was extracted from the Homoserine_transacetylase family
Interpro : IPR008220 Homoserine\/serine acetyltransferase MetX-like HAT_MetX-like , IPR000073 Alpha\/beta hydrolase fold-1
PIRSF : PIRSF000443 homoserine acetyltransferase
Pdoc : No Pdoc
Pfam : PF00561 Abhydrolase_1
Prints : No Print
EC Number : No EC Number
Structures (4)
Genes Proteins in Homoserine_transacetylase_like_est family (14)
No fragment of genes
Structures in Homoserine_transacetylase_like_est family (4)Substrates in Homoserine_transacetylase_like_est family (3)
No Inhibitor
Title : A novel esterase subfamily with alpha\/beta-hydrolase fold suggested by structures of two bacterial enzymes homologous to l-homoserine O-acetyl transferases - Tolzer_2016_FEBS.Lett_590_174 |
Author(s) : Tolzer C , Pal S , Watzlawick H , Altenbuchner J , Niefind K |
Ref : FEBS Letters , 590 :174 , 2016 |
Abstract : Tolzer_2016_FEBS.Lett_590_174 |
ESTHER : Tolzer_2016_FEBS.Lett_590_174 |
PubMedSearch : Tolzer_2016_FEBS.Lett_590_174 |
PubMedID: 26787467 |
Gene_locus related to this paper: 9psed-q0mrg5 |