arath-KAI2.D14L

Arabidopsis thaliana (Mouse-ear cress) At4g37470 KAI2 AtKAI2 HTL hyposensitive to light

Comment

orthologue to rice OsDLK1 paralogue to AtD14 DWARF14 || KARRIKIN INSENSITIVE2 (KAI2) karrikin receptor. Involved in seed germination and seedling development. Essential for plant responses to karrikins, a class of butenolide compounds, structurally similar to strigolactones, released from burning vegetation that stimulate seed germination and enhance seedling photomorphogenesis. KAI2 is not required for strigolactone-mediated responses, but MAX2 is necessary for responses to karrikins and strigolactones. Lacks detectable hydrolase activity against karrikin. Karrikin binding induces a conformational change. Mutations in KAI2, encoding the proposed karrikin receptor, result in hypersensitivity to water deprivation. HYPOSENSITIVE TO LIGHT or HTL. Mutant displayed a long hypocotyl phenotype under red, far-red, and blue light

Relationship

Family : RsbQ-like

Block : X

Position in NCBI Life Tree : Arabidopsis thaliana

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Viridiplantae N E > Streptophyta N E > Streptophytina N E > Embryophyta N E > Tracheophyta N E > Euphyllophyta N E > Spermatophyta N E > Magnoliophyta N E > Mesangiospermae N E > eudicotyledons N E > Gunneridae N E > Pentapetalae N E > rosids N E > malvids N E > Brassicales N E > Brassicaceae N E > Camelineae N E > Arabidopsis N E > Arabidopsis thaliana N E

Database

Sequence

Peptide

MGVVEEAHNV KVIGSGEATI VLGHGFGTDQ SVWKHLVPHL VDDYRVVLYD NMGAGTTNPD YFDFDRYSNL EGYSFDLIAI LEDLKIESCI FVGHSVSAMI GVLASLNRPD LFSKIVMISA SPRYVNDVDY QGGFEQEDLN QLFEAIRSNY KAWCLGFAPL AVGGDMDSIA VQEFSRTLFN MRPDIALSVG QTIFQSDMRQ ILPFVTVPCH ILQSVKDLAV PVVVSEYLHA NLGCESVVEV IPSDGHLPQL SSPDSVIPVI LRHIRNDIAM

References (16)

Title : KAI2 regulates seedling development by mediating light-induced remodelling of auxin transport - Hamon-Josse_2022_New.Phytol_235_126
Author(s) : Hamon-Josse M , Villaecija-Aguilar JA , Ljung K , Leyser O , Gutjahr C , Bennett T
Ref : New Phytol , 235 :126 , 2022
Abstract :
PubMedSearch : Hamon-Josse_2022_New.Phytol_235_126
PubMedID: 35313031
Gene_locus related to this paper: arath-KAI2.D14L

Title : KAI2 promotes Arabidopsis root hair elongation at low external phosphate by controlling local accumulation of AUX1 and PIN2 - Villaecija-Aguilar_2021_Curr.Biol__
Author(s) : Villaecija-Aguilar JA , Korosy C , Maisch L , Hamon-Josse M , Petrich A , Magosch S , Chapman P , Bennett T , Gutjahr C
Ref : Current Biology , : , 2021
Abstract :
PubMedSearch : Villaecija-Aguilar_2021_Curr.Biol__
PubMedID: 34758285
Gene_locus related to this paper: arath-KAI2.D14L

Title : Desmethyl butenolides are optimal ligands for karrikin receptor proteins - Yao_2021_New.Phytol__
Author(s) : Yao J , Scaffidi A , Meng Y , Melville KT , Komatsu A , Khosla A , Nelson DC , Kyozuka J , Flematti GR , Waters MT
Ref : New Phytol , : , 2021
Abstract :
PubMedSearch : Yao_2021_New.Phytol__
PubMedID: 33474738
Gene_locus related to this paper: arath-AtD14 , arath-KAI2.D14L

Title : Three mutations repurpose a plant karrikin receptor to a strigolactone receptor - Arellano-Saab_2021_Proc.Natl.Acad.Sci.U.S.A_118_
Author(s) : Arellano-Saab A , Bunsick M , Al Galib H , Zhao W , Schuetz S , Bradley JM , Xu Z , Adityani C , Subha A , McKay H , de Saint Germain A , Boyer FD , McErlean CSP , Toh S , McCourt P , Stogios PJ , Lumba S
Ref : Proc Natl Acad Sci U S A , 118 : , 2021
Abstract :
PubMedSearch : Arellano-Saab_2021_Proc.Natl.Acad.Sci.U.S.A_118_
PubMedID: 34301902
Gene_locus related to this paper: arath-AtD14 , arath-KAI2.D14L

Title : Synthetic agonist of HTL\/KAI2 shows potent stimulating activity for Arabidopsis seed germination - Fukui_2019_Bioorg.Med.Chem.Lett_29_2487
Author(s) : Fukui K , Arai K , Kasahara H , Asami T , Hayashi KI
Ref : Bioorganic & Medicinal Chemistry Lett , 29 :2487 , 2019
Abstract :
PubMedSearch : Fukui_2019_Bioorg.Med.Chem.Lett_29_2487
PubMedID: 31345632
Gene_locus related to this paper: arath-KAI2.D14L

Title : An allelic series at the KARRIKIN INSENSITIVE 2 locus of Arabidopsis thaliana decouples ligand hydrolysis and receptor degradation from downstream signalling - Yao_2018_Plant.J_96_75
Author(s) : Yao J , Mashiguchi K , Scaffidi A , Akatsu T , Melville KT , Morita R , Morimoto Y , Smith SM , Seto Y , Flematti GR , Yamaguchi S , Waters MT
Ref : Plant J , 96 :75 , 2018
Abstract :
PubMedSearch : Yao_2018_Plant.J_96_75
PubMedID: 29982999
Gene_locus related to this paper: arath-KAI2.D14L

Title : A missense allele of KARRIKIN-INSENSITIVE2 impairs ligand-binding and downstream signaling in Arabidopsis thaliana - Lee_2018_J.Exp.Bot_69_3609
Author(s) : Lee I , Kim K , Lee S , Hwang E , Shin K , Kim D , Choi J , Choi H , Cha JS , Kim H , Lee RA , Jeong S , Kim J , Kim Y , Nam HG , Park SK , Cho HS , Soh MS
Ref : J Exp Bot , 69 :3609 , 2018
Abstract :
PubMedSearch : Lee_2018_J.Exp.Bot_69_3609
PubMedID: 29722815
Gene_locus related to this paper: arath-KAI2.D14L

Title : Rationally Designed Strigolactone Analogs as Antagonists of the D14 Receptor - Takeuchi_2018_Plant.Cell.Physiol_59_1545
Author(s) : Takeuchi J , Jiang K , Hirabayashi K , Imamura Y , Wu Y , Xu Y , Miyakawa T , Nakamura H , Tanokura M , Asami T
Ref : Plant Cell Physiol , 59 :1545 , 2018
Abstract :
PubMedSearch : Takeuchi_2018_Plant.Cell.Physiol_59_1545
PubMedID: 29727000
Gene_locus related to this paper: arath-AtD14 , arath-KAI2.D14L

Title : The karrikin receptor KAI2 promotes drought resistance in Arabidopsis thaliana - Li_2017_PLoS.Genet_13_e1007076
Author(s) : Li W , Nguyen KH , Chu HD , Ha CV , Watanabe Y , Osakabe Y , Leyva-Gonzalez MA , Sato M , Toyooka K , Voges L , Tanaka M , Mostofa MG , Seki M , Seo M , Yamaguchi S , Nelson DC , Tian C , Herrera-Estrella L , Tran LP
Ref : PLoS Genet , 13 :e1007076 , 2017
Abstract :
PubMedSearch : Li_2017_PLoS.Genet_13_e1007076
PubMedID: 29131815
Gene_locus related to this paper: arath-KAI2.D14L

Title : Substrate-Induced Degradation of the alpha\/beta-Fold Hydrolase KARRIKIN INSENSITIVE2 Requires a Functional Catalytic Triad but Is Independent of MAX2 -
Author(s) : Waters MT , Scaffidi A , Flematti GR , Smith SM
Ref : Mol Plant , 8 :814 , 2015
PubMedID: 25698586
Gene_locus related to this paper: arath-KAI2.D14L

Title : The Structure of the Karrikin-Insensitive Protein (KAI2) in Arabidopsis thaliana. - Bythell-Douglas_2013_PLoS.One_8_e54758
Author(s) : Bythell-Douglas R , Waters MT , Scaffidi A , Flematti GR , Smith SM , Bond CS
Ref : PLoS ONE , 8 :e54758 , 2013
Abstract :
PubMedSearch : Bythell-Douglas_2013_PLoS.One_8_e54758
PubMedID: 23349965
Gene_locus related to this paper: arath-KAI2.D14L

Title : KAI2- and MAX2-Mediated Responses to Karrikins and Strigolactones Are Largely Independent of HY5 in Arabidopsis Seedlings - Waters_2013_Mol.Plant_6_63
Author(s) : Waters MT , Smith SM
Ref : Mol Plant , 6 :63 , 2013
Abstract :
PubMedSearch : Waters_2013_Mol.Plant_6_63
PubMedID: 23142794
Gene_locus related to this paper: arath-KAI2.D14L

Title : Structures of D14 and D14L in the strigolactone and karrikin signaling pathways - Kagiyama_2013_Genes.Cells_18_147
Author(s) : Kagiyama M , Hirano Y , Mori T , Kim SY , Kyozuka J , Seto Y , Yamaguchi S , Hakoshima T
Ref : Genes Cells , 18 :147 , 2013
Abstract :
PubMedSearch : Kagiyama_2013_Genes.Cells_18_147
PubMedID: 23301669
Gene_locus related to this paper: arath-KAI2.D14L , orysj-Q10QA5

Title : Specialisation within the DWARF14 protein family confers distinct responses to karrikins and strigolactones in Arabidopsis. - Waters_2012_Development_139_1285
Author(s) : Waters MT , Nelson DC , Scaffidi A , Flematti GR , Sun YK , Dixon KW , Smith SM
Ref : Development , 139 :1285 , 2012
Abstract :
PubMedSearch : Waters_2012_Development_139_1285
PubMedID: 22357928
Gene_locus related to this paper: arath-AtD14 , arath-KAI2.D14L , orysj-q10j20 , orysj-Q10QA5

Title : HYPOSENSITIVE TO LIGHT, an alpha\/beta fold protein, acts downstream of ELONGATED HYPOCOTYL 5 to regulate seedling de-etiolation - Sun_2011_Mol.Plant_4_116
Author(s) : Sun XD , Ni M
Ref : Mol Plant , 4 :116 , 2011
Abstract :
PubMedSearch : Sun_2011_Mol.Plant_4_116
PubMedID: 20864454
Gene_locus related to this paper: arath-KAI2.D14L

Title : Analysis of 1.9 Mb of contiguous sequence from chromosome 4 of Arabidopsis thaliana. - Bevan_1998_Nature_391_485
Author(s) : Bevan M , Bancroft I , Bent E , Love K , Goodman H , Dean C , Bergkamp R , Dirkse W , van Staveren M , Stiekema W , Drost L , Ridley P , Hudson SA , Patel K , Murphy G , Piffanelli P , Wedler H , Wedler E , Wambutt R , Weitzenegger T , Pohl TM , Terryn N , Gielen J , Villarroel R , De Clerck R , van Montagu M , Lecharny A , Auborg S , Gy I , Kreis M , Lao N , Kavanagh T , Hempel S , Kotter P , Entian KD , Rieger M , Schaeffer M , Funk B , Mueller-Auer S , Silvey M , James R , Montfort A , Pons A , Puigdomenech P , Douka A , Voukelatou E , Milioni D , Hatzopoulos P , Piravandi E , Obermaier B , Hilbert H , Duesterhoft A , Moores T , Jones JDG , Eneva T , Palme K , Benes V , Rechman S , Ansorge W , Cooke R , Berger C , Delseny M , Voet M , Volckaert G , Mewes HW , Klosterman S , Schueller C , Chalwatzis N
Ref : Nature , 391 :485 , 1998
Abstract :
PubMedSearch : Bevan_1998_Nature_391_485
PubMedID: 9461215
Gene_locus related to this paper: arath-a4vcl8 , arath-AT4G00500 , arath-AT4g09900 , arath-AT4g12830 , arath-AT4G14290 , arath-AT4G15100 , arath-AT4G16070 , arath-AT4G16690 , arath-AT4G17150 , arath-AT4G17470 , arath-AT4G17480 , arath-AT4G17483 , arath-At4g18550 , arath-SOBR1 , arath-SOBRL , arath-AT4G24380 , arath-AT4G25770 , arath-AT4g30610 , arath-AT4G31020 , arath-AT4G36195 , arath-AT4G37150 , arath-SCP29 , arath-At3g54240 , arath-KAI2.D14L