Gene_locus Report for: ailme-BCHE Ailuropoda melanoleuca (Giant panda) Putative uncharacterized protein
Relationship
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Deuterostomia: N E > Chordata: N E > Craniata: N E > Vertebrata: N E > Gnathostomata: N E > Teleostomi: N E > Euteleostomi: N E > Sarcopterygii: N E > Dipnotetrapodomorpha: N E > Tetrapoda: N E > Amniota: N E > Mammalia: N E > Theria: N E > Eutheria: N E > Boreoeutheria: N E > Laurasiatheria: N E > Carnivora: N E > Caniformia: N E > Ursidae: N E > Ailuropoda: N E > Ailuropoda melanoleuca: N E ABHD6-Lip :
ailme-d2gx08 Ailuropoda melanoleuca (Giant panda) Uncharacterized protein .
ABHD8 :
ailme-d2gv02 Ailuropoda melanoleuca (Giant panda). Uncharacterized protein .
ABHD10 :
ailme-g1mik5 Ailuropoda melanoleuca (Giant panda). Abhydrolase domain containing 10 .
ABHD11-Acetyl_transferase :
ailme-g1lxw7 Ailuropoda melanoleuca (Giant panda). Abhydrolase domain containing 11 .
ABHD12-PHARC :
ailme-g1lu36 Ailuropoda melanoleuca (Giant panda) Uncharacterized protein .
ABHD13-BEM46 :
ailme-d2h2r2 Ailuropoda melanoleuca (Giant panda). Abhydrolase domain containing 13 .
ABHD16 :
ailme-g1lrp4 Ailuropoda melanoleuca (Giant panda). Abhydrolase domain containing 16A .
ABHD18 :
ailme-g1l7l1 Ailuropoda melanoleuca (Giant panda).ABHD18 Uncharacterized protein .
abh_upf0017 :
ailme-ABH15 Ailuropoda melanoleuca (Giant panda) Abhydrolase domain containing 15 ,
ailme-d2hcd9 Ailuropoda melanoleuca (Giant panda) alpha/beta hydrolase domain containing protein 2 ,
ailme-d2hzr4 Ailuropoda melanoleuca (Giant panda) Putative uncharacterized protein .
ACHE :
ailme-ACHE Ailuropoda melanoleuca (Giant panda) Uncharacterized protein .
Acidic_Lipase :
ailme-d2gz36 Ailuropoda melanoleuca (Giant panda) Putative uncharacterized protein ,
ailme-d2gz37 Ailuropoda melanoleuca (Giant panda) Lipase ,
ailme-d2gz38 Ailuropoda melanoleuca (Giant panda) Lipase ,
ailme-d2gz39 Ailuropoda melanoleuca (Giant panda) Lipase ,
ailme-d2gz40 Ailuropoda melanoleuca (Giant panda) Lipase .
ACPH_Peptidase_S9 :
ailme-d2heu6 Ailuropoda melanoleuca (Giant panda) Putative uncharacterized protein .
Arb2_FAM172A :
ailme-g1ljr1 Ailuropoda melanoleuca (Giant panda). Uncharacterized protein .
Arylacetamide_deacetylase :
ailme-g1l2f6 Ailuropoda melanoleuca (Giant panda). Uncharacterized protein ,
ailme-g1lji5 Ailuropoda melanoleuca (Giant panda). Uncharacterized protein ,
ailme-g1lqk3 Ailuropoda melanoleuca (Giant panda). Uncharacterized protein .
Carboxypeptidase_S10 :
ailme-d2hz11 Ailuropoda melanoleuca (Giant panda) Uncharacterized protein .
Carb_B_Chordata :
ailme-d2gtv3 Ailuropoda melanoleuca (Giant panda) Putative uncharacterized protein ,
ailme-d2h9c9 Ailuropoda melanoleuca (Giant panda) Putative uncharacterized protein ,
ailme-g1mdr5 Ailuropoda melanoleuca (Giant panda) Uncharacterized protein ,
ailme-g1mfp4 Ailuropoda melanoleuca (Giant panda) Uncharacterized protein .
CGI-58_ABHD5_ABHD4 :
ailme-d2htv3 Ailuropoda melanoleuca (Giant panda) Putative uncharacterized protein ,
ailme-d2hwy7 Ailuropoda melanoleuca (Giant panda) Putative uncharacterized protein .
CIB-CCG1-interacting-factor-B :
ailme-d2hau7 Ailuropoda melanoleuca (Giant panda) Putative uncharacterized protein ,
ailme-d2hau8 Ailuropoda melanoleuca (Giant panda) Putative uncharacterized protein .
CMBL :
ailme-d2h9w7 Ailuropoda melanoleuca (Giant panda). Carboxymethylenebutenolidase homolog .
DPP4N_Peptidase_S9 :
ailme-d2gyt0 Ailuropoda melanoleuca (Giant panda) Putative uncharacterized protein ,
ailme-d2hga4 Ailuropoda melanoleuca (Giant panda) Putative uncharacterized protein ,
ailme-d2hqw5 Ailuropoda melanoleuca (Giant panda) Putative uncharacterized protein ,
ailme-d2htz6 Ailuropoda melanoleuca (Giant panda) Putative uncharacterized protein ,
ailme-d2i2g8 Ailuropoda melanoleuca (Giant panda) Putative uncharacterized protein .
Duf_676 :
ailme-d2hti6 Ailuropoda melanoleuca (Giant panda) Putative uncharacterized protein ,
ailme-d2hyv2 Ailuropoda melanoleuca (Giant panda) Putative uncharacterized protein .
Epoxide_hydrolase :
ailme-d2huc7 Ailuropoda melanoleuca (Giant panda) Putative uncharacterized protein ,
ailme-d2hza3 Ailuropoda melanoleuca (Giant panda) Putative uncharacterized protein .
FSH1 :
ailme-d2h8b5 Ailuropoda melanoleuca (Giant panda). FSH1 domain-containing protein .
Hepatic_Lipase :
ailme-g1l8s9 Ailuropoda melanoleuca (Giant panda). Uncharacterized protein .
Hydrolase_RBBP9_YdeN :
ailme-d2hsx4 Ailuropoda melanoleuca (Giant panda) Putative uncharacterized protein .
Kynurenine-formamidase :
ailme-g1m5i3 Ailuropoda melanoleuca (Giant panda). Uncharacterized protein .
Lipoprotein_Lipase :
ailme-g1l2a1 Ailuropoda melanoleuca (Giant panda). Lipoprotein lipase ,
ailme-g1lsc8 Ailuropoda melanoleuca (Giant panda). Lipase G, endothelial type .
Maspardin-ACP33-SPG21_like :
ailme-g1l7m3 Ailuropoda melanoleuca (Giant panda) Uncharacterized protein .
MEST-like :
ailme-d2gwu1 Ailuropoda melanoleuca (Giant panda) Putative uncharacterized protein .
Monoglyceridelipase_lysophospholip :
ailme-d2h7b7 Ailuropoda melanoleuca (Giant panda) Putative uncharacterized protein .
Ndr_family :
ailme-d2gty9 Ailuropoda melanoleuca (Giant panda) Putative uncharacterized protein ,
ailme-d2hyc8 Ailuropoda melanoleuca (Giant panda) Putative uncharacterized protein ,
ailme-g1mfx5 Ailuropoda melanoleuca (Giant panda) Uncharacterized protein ,
ailme-g1lj41 Ailuropoda melanoleuca (Giant panda) Uncharacterized protein ,
ailme-g1lm28 Ailuropoda melanoleuca (Giant panda) Uncharacterized protein ,
ailme-g1l3u1 Ailuropoda melanoleuca (Giant panda) Uncharacterized protein .
Neuroligin :
ailme-d2i1l4 Ailuropoda melanoleuca (Giant panda) Putative uncharacterized protein ,
ailme-g1mc29 Ailuropoda melanoleuca (Giant panda) Uncharacterized protein .
NLS3-Tex30 :
ailme-d2gu87 Ailuropoda melanoleuca (Giant panda) Putative uncharacterized protein ,
ailme-g1mdj8 Ailuropoda melanoleuca (Giant panda) Uncharacterized protein .
Palmitoyl-protein_thioesterase :
ailme-d2hxm1 Ailuropoda melanoleuca (Giant panda) Putative uncharacterized protein .
Pancreatic_lipase :
ailme-d2h717 Ailuropoda melanoleuca (Giant panda). Uncharacterized protein ,
ailme-d2h718 Ailuropoda melanoleuca (Giant panda). Uncharacterized protein ,
ailme-d2h719 Ailuropoda melanoleuca (Giant panda). Uncharacterized protein ,
ailme-d2h720 Ailuropoda melanoleuca (Giant panda). Uncharacterized protein ,
ailme-g1m5v0 Ailuropoda melanoleuca (Giant panda). Pancreatic lipase ,
ailme-g1m5y7 Ailuropoda melanoleuca (Giant panda). Pancreatic lipase .
Pectinacetylesterase-Notum :
ailme-d2gve7 Ailuropoda melanoleuca (Giant panda) Putative uncharacterized protein .
PGAP1 :
ailme-d2hdi6 Ailuropoda melanoleuca (Giant panda) Uncharacterized protein .
Phospholipase :
ailme-g1lkt7 Ailuropoda melanoleuca (Giant panda). Phospholipase A1 member A ,
ailme-g1meh3 Ailuropoda melanoleuca (Giant panda). Lipase H ,
ailme-g1m719 Ailuropoda melanoleuca (Giant panda). Lipase I .
Prolylcarboxypeptidase :
ailme-d2hs98 Ailuropoda melanoleuca (Giant panda) Putative uncharacterized protein ,
ailme-d2hwj8 Ailuropoda melanoleuca (Giant panda) Putative uncharacterized protein .
S9N_PPCE_Peptidase_S9 :
ailme-d2h5r9 Ailuropoda melanoleuca (Giant panda) Putative uncharacterized protein .
S9N_PREPL_Peptidase_S9 :
ailme-d2gu97 Ailuropoda melanoleuca (Giant panda) Uncharacterized protein .
Thyroglobulin :
ailme-d2h794 Ailuropoda melanoleuca (Giant panda) Putative uncharacterized protein .
Valacyclovir-hydrolase :
ailme-g1m769 Ailuropoda melanoleuca (Giant panda) Uncharacterized protein Molecular evidence
Database
No mutation No structure No kinetic No Substrate No inhibitor
Sequence
Graphical view for this peptide sequence: ailme-BCHE Colored MSA for BCHE (raw)
MQSKGMIISVRFLLRFLLLWVLIGKSHMEEDIVITTKNGKVRGVSLPVLG
GTVTAFLGIPYAQPPLGRLRFKKPQFLTKWSDIWNATKYANSCYQNTDQS
FPGFPGSEMWNPNTDLSEDCLYLNVWVPTPKPKNATVMIWIYGGGFQTGT
SSLPVYDGKFLARVETVIVVSMNYRVGALGFLALPGNPEVPGNMGLFDQQ
LALQWVQKNIAAFGGNPKSVTLFGESAGAGSVSLHLLSPRSQPLFTRAIL
QSGSSNAPWAVMSLDEARNRTLTLAKFIGCSRENETEIIKCLRNKDPQEI
LLNEVLVVPSDTLLSVNFGPVVDGDFLTDMPDTLLQLGQLKKAQILVGVN
KDEGTAFLVYGAPGFSKDNDSIITRKDFQEGLKMYFPGVSEFGRESILFY
YADLLDDQRAEKYRDALDDVLGDYNIICPALEFTKKFSELGNNAFFYYFE
HQSSKLPWPEWMGVMHGYEIEFVFGLPLERRANYTKAEEILSRSIMKYWA
NFAKYGNPDGTRNNSTRWPVFKNTDQKYLTLTTESPRVYTKLRAQQCRFW
TLFFPKILEMTGNIDEAEREWRAGFYRWNNYMMDWKNQFNDYTSKKESCA
GL
Legend
This sequence has been compared to family alignement (MSA) red => minority aminoacid blue => majority aminoacid color intensity => conservation rate title => sequence position(MSA position)aminoacid rate Catalytic site Catalytic site in the MSA
M Q S K G M I I S V R F L L R F L L L W V L I G K S H M E E D I V I T T K N G K V R G V S L P V L G G T V T A F L G I P Y A Q P P L G R L R F K K P Q F L T K W S D I W N A T K Y A N S C Y Q N T D Q S F P G F P G S E M W N P N T D L S E D C L Y L N V W V P T P K P K N A T V M I W I Y G G G F Q T G T S S L P V Y D G K F L A R V E T V I V V S M N Y R V G A L G F L A L P G N P E V P G N M G L F D Q Q L A L Q W V Q K N I A A F G G N P K S V T L F G E S A G A G S V S L H L L S P R S Q P L F T R A I L Q S G S S N A P W A V M S L D E A R N R T L T L A K F I G C S R E N E T E I I K C L R N K D P Q E I L L N E V L V V P S D T L L S V N F G P V V D G D F L T D M P D T L L Q L G Q L K K A Q I L V G V N K D E G T A F L V Y G A P G F S K D N D S I I T R K D F Q E G L K M Y F P G V S E F G R E S I L F Y Y A D L L D D Q R A E K Y R D A L D D V L G D Y N I I C P A L E F T K K F S E L G N N A F F Y Y F E H Q S S K L P W P E W M G V M H G Y E I E F V F G L P L E R R A N Y T K A E E I L S R S I M K Y W A N F A K Y G N P D G T R N N S T R W P V F K N T D Q K Y L T L T T E S P R V Y T K L R A Q Q C R F W T L F F P K I L E M T G N I D E A E R E W R A G F Y R W N N Y M M D W K N Q F N D Y T S K K E S C A G L
References
Title: Impacts of the Cretaceous Terrestrial Revolution and KPg extinction on mammal diversificationMeredith RW , Janecka JE , Gatesy J , Ryder OA , Fisher CA , Teeling EC , Goodbla A , Eizirik E , Simao TL and Murphy WJ <12 more author(s)> Meredith RW , Janecka JE , Gatesy J , Ryder OA , Fisher CA , Teeling EC , Goodbla A , Eizirik E , Simao TL , Stadler T , Rabosky DL , Honeycutt RL , Flynn JJ , Ingram CM , Steiner C , Williams TL , Robinson TJ , Burk-Herrick A , Westerman M , Ayoub NA , Springer MS , Murphy WJ (- 12) Ref: Science, 334 :521, 2011 : PubMed Abstract ESTHER: Meredith_2011_Science_334_521 PubMedSearch: Meredith 2011 Science 334 521 PubMedID: 21940861 Gene_locus related to this paper: ailme-BCHE ,
hetga-g5atg6 ,
pig-BCHE Abstract
Previous analyses of relations, divergence times, and diversification patterns among extant mammalian families have relied on supertree methods and local molecular clocks. We constructed a molecular supermatrix for mammalian families and analyzed these data with likelihood-based methods and relaxed molecular clocks. Phylogenetic analyses resulted in a robust phylogeny with better resolution than phylogenies from supertree methods. Relaxed clock analyses support the long-fuse model of diversification and highlight the importance of including multiple fossil calibrations that are spread across the tree. Molecular time trees and diversification analyses suggest important roles for the Cretaceous Terrestrial Revolution and Cretaceous-Paleogene (KPg) mass extinction in opening up ecospace that promoted interordinal and intraordinal diversification, respectively. By contrast, diversification analyses provide no support for the hypothesis concerning the delayed rise of present-day mammals during the Eocene Period.
Title: The sequence and de novo assembly of the giant panda genomeLi R , Fan W , Tian G , Zhu H , He L , Cai J , Huang Q , Cai Q , Li B and Yang H <103 more author(s)> Li R , Fan W , Tian G , Zhu H , He L , Cai J , Huang Q , Cai Q , Li B , Bai Y , Zhang Z , Zhang Y , Wang W , Li J , Wei F , Li H , Jian M , Nielsen R , Li D , Gu W , Yang Z , Xuan Z , Ryder OA , Leung FC , Zhou Y , Cao J , Sun X , Fu Y , Fang X , Guo X , Wang B , Hou R , Shen F , Mu B , Ni P , Lin R , Qian W , Wang G , Yu C , Nie W , Wang J , Wu Z , Liang H , Min J , Wu Q , Cheng S , Ruan J , Wang M , Shi Z , Wen M , Liu B , Ren X , Zheng H , Dong D , Cook K , Shan G , Zhang H , Kosiol C , Xie X , Lu Z , Li Y , Steiner CC , Lam TT , Lin S , Zhang Q , Li G , Tian J , Gong T , Liu H , Zhang D , Fang L , Ye C , Zhang J , Hu W , Xu A , Ren Y , Zhang G , Bruford MW , Li Q , Ma L , Guo Y , An N , Hu Y , Zheng Y , Shi Y , Li Z , Liu Q , Chen Y , Zhao J , Qu N , Zhao S , Tian F , Wang X , Wang H , Xu L , Liu X , Vinar T , Wang Y , Lam TW , Yiu SM , Liu S , Huang Y , Yang G , Jiang Z , Qin N , Li L , Bolund L , Kristiansen K , Wong GK , Olson M , Zhang X , Li S , Yang H (- 103) Ref: Nature, 463 :311, 2010 : PubMed Abstract ESTHER: Li_2010_Nature_463_311 PubMedSearch: Li 2010 Nature 463 311 PubMedID: 20010809 Gene_locus related to this paper: ailme-ABH15 ,
ailme-ACHE ,
ailme-BCHE ,
ailme-d2gtv3 ,
ailme-d2gty9 ,
ailme-d2gu87 ,
ailme-d2gu97 ,
ailme-d2gve7 ,
ailme-d2gwu1 ,
ailme-d2gx08 ,
ailme-d2gyt0 ,
ailme-d2gz36 ,
ailme-d2gz37 ,
ailme-d2gz38 ,
ailme-d2gz39 ,
ailme-d2gz40 ,
ailme-d2h5r9 ,
ailme-d2h7b7 ,
ailme-d2h9c9 ,
ailme-d2h794 ,
ailme-d2hau7 ,
ailme-d2hau8 ,
ailme-d2hcd9 ,
ailme-d2hdi6 ,
ailme-d2heu6 ,
ailme-d2hga4 ,
ailme-d2hqw5 ,
ailme-d2hs98 ,
ailme-d2hsx4 ,
ailme-d2hti6 ,
ailme-d2htv3 ,
ailme-d2htz6 ,
ailme-d2huc7 ,
ailme-d2hwj8 ,
ailme-d2hwy7 ,
ailme-d2hxm1 ,
ailme-d2hyc8 ,
ailme-d2hyv2 ,
ailme-d2hz11 ,
ailme-d2hza3 ,
ailme-d2hzr4 ,
ailme-d2i1l4 ,
ailme-d2i2g8 ,
ailme-g1l7m3 ,
ailme-g1lu36 ,
ailme-g1m769 ,
ailme-g1mc29 ,
ailme-g1mdj8 ,
ailme-g1mdr5 ,
ailme-g1mfp4 ,
ailme-g1mfx5 ,
ailme-g1lj41 ,
ailme-g1lm28 ,
ailme-g1l3u1 ,
ailme-g1l7l1 ,
ailme-g1m5i3 ,
ailme-g1l2f6 ,
ailme-g1lji5 ,
ailme-g1lqk3 ,
ailme-g1l8s9 ,
ailme-d2h717 ,
ailme-d2h718 ,
ailme-d2h719 ,
ailme-d2h720 ,
ailme-g1m5v0 ,
ailme-g1m5y7 ,
ailme-g1lkt7 ,
ailme-g1l2a1 ,
ailme-g1lsc8 ,
ailme-g1lrp4 ,
ailme-d2gv02 ,
ailme-g1mik5 ,
ailme-g1ljr1 ,
ailme-g1lxw7 ,
ailme-d2h8b5 ,
ailme-d2h2r2 ,
ailme-d2h9w7 ,
ailme-g1meh3 ,
ailme-g1m719 Abstract
Using next-generation sequencing technology alone, we have successfully generated and assembled a draft sequence of the giant panda genome. The assembled contigs (2.25 gigabases (Gb)) cover approximately 94% of the whole genome, and the remaining gaps (0.05 Gb) seem to contain carnivore-specific repeats and tandem repeats. Comparisons with the dog and human showed that the panda genome has a lower divergence rate. The assessment of panda genes potentially underlying some of its unique traits indicated that its bamboo diet might be more dependent on its gut microbiome than its own genetic composition. We also identified more than 2.7 million heterozygous single nucleotide polymorphisms in the diploid genome. Our data and analyses provide a foundation for promoting mammalian genetic research, and demonstrate the feasibility for using next-generation sequencing technologies for accurate, cost-effective and rapid de novo assembly of large eukaryotic genomes.
Other Papers
