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Gene_locus Report for: cavpo-a0a286xtc0

Cavia porcellus (Guinea pig). Lipase I

Relationship
Family|Phospholipase
Block| L
Position in NCBI Life Tree|Cavia porcellus
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Deuterostomia: N E > Chordata: N E > Craniata: N E > Vertebrata: N E > Gnathostomata: N E > Teleostomi: N E > Euteleostomi: N E > Sarcopterygii: N E > Dipnotetrapodomorpha: N E > Tetrapoda: N E > Amniota: N E > Mammalia: N E > Theria: N E > Eutheria: N E > Boreoeutheria: N E > Euarchontoglires: N E > Glires: N E > Rodentia: N E > Hystricomorpha: N E > Caviidae: N E > Cavia: N E > Cavia porcellus: N E


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
3 Genbank : AAKN02034405, AAKN02034406, AAKN02034407
1 UniProt : A0A286XTC0
1 UniProt : A0A286XTC0
1 Interpro : A0A286XTC0
1 Prodom : A0A286XTC0
1 Pfam : A0A286XTC0
1 PIRSF : A0A286XTC0
1 SUPERFAM : A0A286XTC0
Sequence
Graphical view for this peptide sequence: cavpo-a0a286xtc0
Colored MSA for Phospholipase (raw)
MRVYIFLCLMCCIRSGYFSLSTKSTPVSRKSFENRRLCLEFSKLNVKDSL
KELFIHRLKIILMLYTRNNFNCAEPLFQQNNSVNINFNKHRKTVWLIHGY
RPVGSTPSWLHKFVWTLLNKEDVNLIVVDWNQGAATFIYNRAVKNTRKVA
EVLSRYIQNLLVQGASLENFHFIGISLGAHICGFVGKIFHGELGRITGLD
PAGPKFSGKPSNSRLDYTDAKLVDVIHSDVDGLGIQEPLGHIDFYPNGGK
NQPGCPTSIFSGIEYIKCDHQRAVYLFMAALQTNCSFVSFPCHSYKDYKT
SLCVDCGSSQKNSCPRLEYYTEHWEHSLKTRTKKWPVRITTFFDTSGRYP
FCAYYFVLSITALDESMNDGYISFKVLNQLGVAEYSRVYEKSKPFHKLQE
VNILAQFLNDVVNISSIVLRYFQTSNIQCPTNKHRIQRLMLKSLTYPERP
PVCSYNFVIKESEELFLKCHMHRE
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MRVYIFLCLMCCIRSGYFSLSTKSTPVSRKSFENRRLCLEFSKLNVKDSL
KELFIHRLKIILMLYTRNNFNCAEPLFQQNNSVNINFNKHRKTVWLIHGY
RPVGSTPSWLHKFVWTLLNKEDVNLIVVDWNQGAATFIYNRAVKNTRKVA
EVLSRYIQNLLVQGASLENFHFIGISLGAHICGFVGKIFHGELGRITGLD
PAGPKFSGKPSNSRLDYTDAKLVDVIHSDVDGLGIQEPLGHIDFYPNGGK
NQPGCPTSIFSGIEYIKCDHQRAVYLFMAALQTNCSFVSFPCHSYKDYKT
SLCVDCGSSQKNSCPRLEYYTEHWEHSLKTRTKKWPVRITTFFDTSGRYP
FCAYYFVLSITALDESMNDGYISFKVLNQLGVAEYSRVYEKSKPFHKLQE
VNILAQFLNDVVNISSIVLRYFQTSNIQCPTNKHRIQRLMLKSLTYPERP
PVCSYNFVIKESEELFLKCHMHRE


Reference
    Title: A high-resolution map of human evolutionary constraint using 29 mammals
    Lindblad-Toh K, Garber M, Zuk O, Lin MF, Parker BJ, Washietl S, Kheradpour P, Ernst J, Jordan G and Kellis M <76 more author(s)>
    Ref: Nature, 478:476, 2011 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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