Gene_Locus Report

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Gene_locus Report for: myolu-g1par4

Myotis lucifugus (Little brown bat). Pancreatic lipase

Relationship
Family|Pancreatic_lipase
Block| L
Position in NCBI Life Tree|Myotis lucifugus
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Deuterostomia: N E > Chordata: N E > Craniata: N E > Vertebrata: N E > Gnathostomata: N E > Teleostomi: N E > Euteleostomi: N E > Sarcopterygii: N E > Dipnotetrapodomorpha: N E > Tetrapoda: N E > Amniota: N E > Mammalia: N E > Theria: N E > Eutheria: N E > Boreoeutheria: N E > Laurasiatheria: N E > Chiroptera: N E > Microchiroptera: N E > Vespertilionidae: N E > Myotis: N E > Myotis lucifugus: N E


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
3 Genbank : AAPE02016469, XP_006088220, AAPE02068819
2 UniProt : G1PAR4, G1PIA0
2 UniProt : G1PAR4, G1PIA0
2 Interpro : G1PAR4, G1PIA0
2 Prodom : G1PAR4, G1PIA0
2 Pfam : G1PAR4, G1PIA0
2 PIRSF : G1PAR4, G1PIA0
2 SUPERFAM : G1PAR4, G1PIA0
Sequence
Graphical view for this peptide sequence: myolu-g1par4
Colored MSA for Pancreatic_lipase (raw)
MVSIWAIALFLLGAVQGKEICYGRLGCFSDSEPWGGTVIRPLKVLPWSPE
KIGTRFLLYTNENPDTFQNLLPSDPSTIEASNFQTDRKTRFIIHGFIDKG
DESWVLKMCKNMFEVEEVNCICVDWKRGSQTTYSQAVNNVRVVGAQVAQM
LDVLKTNYSYSPSQVHLIGHSLGAHVAGEAGSRTPGLGRITGLDPVEASF
QGTSEEVRLDPSDAAFVDVIHTDAAPLIPSLGFGTSQLVGHLDFFPNGGE
EMPGCKKNALSQIVDLDGIWSGTKDFVACNHLRSYKYYADSILNPDGFTA
YPCASYRAFKSNKCFPCPDEGCPQMGHYADKFAGKASPEEQKYFLNTGDS
SSFARWRYGVSVTMSGRMVTGQVKVALFGNKGNTHQYDIFRGVLKPGSTH
SNEFDADLDVGTIEKVKFLWNNHVVNPTFPKVGASKITVQKGEEKTVYNF
CSTDTVREDVLLTLTPC
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MVSIWAIALFLLGAVQGKEICYGRLGCFSDSEPWGGTVIRPLKVLPWSPE
KIGTRFLLYTNENPDTFQNLLPSDPSTIEASNFQTDRKTRFIIHGFIDKG
DESWVLKMCKNMFEVEEVNCICVDWKRGSQTTYSQAVNNVRVVGAQVAQM
LDVLKTNYSYSPSQVHLIGHSLGAHVAGEAGSRTPGLGRITGLDPVEASF
QGTSEEVRLDPSDAAFVDVIHTDAAPLIPSLGFGTSQLVGHLDFFPNGGE
EMPGCKKNALSQIVDLDGIWSGTKDFVACNHLRSYKYYADSILNPDGFTA
YPCASYRAFKSNKCFPCPDEGCPQMGHYADKFAGKASPEEQKYFLNTGDS
SSFARWRYGVSVTMSGRMVTGQVKVALFGNKGNTHQYDIFRGVLKPGSTH
SNEFDADLDVGTIEKVKFLWNNHVVNPTFPKVGASKITVQKGEEKTVYNF
CSTDTVREDVLLTLTPC


Reference
    Title: A high-resolution map of human evolutionary constraint using 29 mammals
    Lindblad-Toh K, Garber M, Zuk O, Lin MF, Parker BJ, Washietl S, Kheradpour P, Ernst J, Jordan G and Kellis M <76 more author(s)>
    Ref: Nature, 478:476, 2011 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page
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