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Inhibitor Report for: DETFP

General
Type Trifluoro, Sulfur Compound, Halo ketone
Chemical_Nomenclature 3-dodecylsulfanyl-1,1,1-trifluoropropan-2-one
Canonical SMILES CCCCCCCCCCCCSCC(=O)C(F)(F)F
InChI InChI=1S/C15H27F3OS/c1-2-3-4-5-6-7-8-9-10-11-12-20-13-14(19)15(16,17)18/h2-13H2,1H3
InChIKey NACMLRDTSWENRZ-UHFFFAOYSA-N
Other name(s) 1,1,1-trifluoro-3-decylsulfanyl-propan-2-one ; 2,2-Dimethyl-3-methyleneheptadecane ; CHEMBL270375 ; 2-Propanone, 3-(dodecylthio)-1,1,1-trifluoro- ; ACMC-20lwey ; D01NDE ; CTK3F7670
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MW|312.43
Formula|C15H27F3OS
CAS_number|92682-28-5
PubChem|11493344
UniChem|NACMLRDTSWENRZ-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | DETFP ligand of proteins in family: Juvenile_hormone_esterase

References:
Search PubMed for references concerning: DETFP
    Title: Juvenile hormone esterase (JHE) from Tenebrio molitor: full-length cDNA sequence, in vitro expression, and characterization of the recombinant protein
    Hinton AC, Hammock BD
    Ref: Insect Biochemistry & Molecular Biology, 33:477, 2003 : PubMed

            

    Title: In vitro expression and biochemical characterization of juvenile hormone esterase from Manduca sexta
    Hinton AC, Hammock BD
    Ref: Insect Biochemistry & Molecular Biology, 33:317, 2003 : PubMed

            

    Title: Substituted thiotrifluoropropanones as potent selective inhibitors of juvenile hormone esterase
    Hammock BD, Abdel-Aalab YAI, Mullin CA, Hanzlik TN, Roe RM
    Ref: Pestic Biochem Physiol, 22:209, 1984 : PubMed