4W63
Name : Torpedo californica Acetylcholinesterase in complex with a tacrine-benzofuran hybrid inhibitor
Revelation date : 09-Sep-2015
Family : ACHE
Gene_locus : torca-ACHE
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Pesaresi, A., Samez, S., Lamba, D.
Ligand : Inhibitor Tacrine-Benzofuran Ligand in structure: Ligplot
References (1)
| Title : Novel Tacrine-Benzofuran Hybrids as Potent Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and X-ray Crystallography - Zha_2016_J.Med.Chem_59_114 |
| Author(s) : Zha X , Lamba D , Zhang L , Lou Y , Xu C , Kang D , Chen L , Xu Y , De Simone A , Samez S , Pesaresi A , Stojan J , Lopez MG , Egea J , Andrisano V , Bartolini M |
| Ref : Journal of Medicinal Chemistry , 59 :114 , 2016 |
| Abstract : |
| PubMedSearch : Zha_2016_J.Med.Chem_59_114 |
| PubMedID: 26632651 |
| Gene_locus related to this paper: torca-ACHE |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
Databases
PDB-Sum : 4W63 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 4W63 Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 4W63 Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 4W63 3D, interactive encyclopedia of proteins - PROTEOPEDIA server