9F6R
Name : Crystal structure of human acetylcholinesterase in complex with the uncharged hybrid reactivator quinoline-3-hydroxy-pyridinaldoxime JDS364
Revelation date : 12-Nov-2025
Family : ACHE
Gene_locus : human-ACHE
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Dias, J.,Nachon, F.
Ligand : Ligand in structure: Ligplot
References (1)
| Title : Design, synthesis and evaluation of an uncharged broad spectrum quinoline-oxime hybrid for the reactivation of nerve agent-inhibited human acetylcholinesterase - De Sousa_2026_Eur.J.Med.Chem_316_119023 |
| Author(s) : de Sousa J , Calas AG , De la Mora E , Landry C , Hanak AS , Maryan-Instone A , Gastellier AJ , Coisne C , Courageux C , Hachani J , Gosselet F , Dehouck MP , Rousseau C , Timperley CM , Weik M , Nachon F , Brown RCD , Baati R , Dias J |
| Ref : Eur Journal of Medicinal Chemistry , 316 :119023 , 2026 |
| Abstract : |
| PubMedSearch : De Sousa_2026_Eur.J.Med.Chem_316_119023 |
| PubMedID: 42241775 |
| Gene_locus related to this paper: human-BCHE |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
Databases
PDB-Sum : 9F6R Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 9F6R Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 9F6R Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 9F6R 3D, interactive encyclopedia of proteins - PROTEOPEDIA server