Lidocaine

General

Type : Local anesthetic, Drug, Not A\/B H target

Chemical_Nomenclature : 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide

Canonical SMILES : CCN(CC)CC(=O)NC1=C(C=CC=C1C)C

InChI : InChI=1S\/C14H22N2O\/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4\/h7-9H,5-6,10H2,1-4H3,(H,15,17)

InChIKey : NNJVILVZKWQKPM-UHFFFAOYSA-N

Other name(s) : Lignocaine  ||  Xylocaine  ||  Anestacon  ||  Esracaine  ||  Gravocain  ||  Leostesin  ||  Maricaine  ||  Cappicaine  ||  Xylestesin


MW : 234.34

Formula : C14H22N2O

CAS_number : 137-58-6

PubChem : 3676

UniChem : NNJVILVZKWQKPM-UHFFFAOYSA-N

IUPHAR : 2623

Wikipedia : Lidocaine

Target

References (2)

Title : Prilocaine- and lidocaine-induced methemoglobinemia is caused by human carboxylesterase-, CYP2E1-, and CYP3A4-mediated metabolic activation - Higuchi_2013_Drug.Metab.Dispos_41_1220
Author(s) : Higuchi R , Fukami T , Nakajima M , Yokoi T
Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 41 :1220 , 2013
Abstract :
PubMedSearch : Higuchi_2013_Drug.Metab.Dispos_41_1220
PubMedID: 23530020

Title : Selective inhibition of carboxylesterases by isatins, indole-2,3-diones - Hyatt_2007_J.Med.Chem_50_1876
Author(s) : Hyatt JL , Moak T , Hatfield MJ , Tsurkan L , Edwards CC , Wierdl M , Danks MK , Wadkins RM , Potter PM
Ref : Journal of Medicinal Chemistry , 50 :1876 , 2007
Abstract :
PubMedSearch : Hyatt_2007_J.Med.Chem_50_1876
PubMedID: 17378546