Resorufin-butyrate

General

Type : Butyrate, Phenoxazin, Derivative of Resorufin, Fluorescent Probe

Chemical_Nomenclature : (7-oxophenoxazin-3-yl) butanoate

Canonical SMILES : CCCC(=O)OC1=CC2=C(C=C1)N=C3C=CC(=O)C=C3O2

InChI : InChI=1S\/C16H13NO4\/c1-2-3-16(19)20-11-5-7-13-15(9-11)21-14-8-10(18)4-6-12(14)17-13\/h4-9H,2-3H2,1H3

InChIKey : RGJTZDRUTUWWTD-UHFFFAOYSA-N

Other name(s) : Resorufin butyrate  ||  butyl resorufin  ||  AC1NMEKF  ||  SCHEMBL12189748  ||  83637_FLUKA


MW : 283.27

Formula : C16H13NO4

CAS_number : 15585-42-9

PubChem : 5007916

UniChem : RGJTZDRUTUWWTD-UHFFFAOYSA-N

Target

Structures : No structure

Families : A85-Mycolyl-transferase, Monoglyceridelipase_lysophospholip

References (5)

Title : Monoacylglycerol Lipase Inhibition in Human and Rodent Systems Supports Clinical Evaluation of Endocannabinoid Modulators - Clapper_2018_J.Pharmacol.Exp.Ther_367_494
Author(s) : Clapper JR , Henry CL , Niphakis MJ , Knize AM , Coppola AR , Simon GM , Ngo N , Herbst RA , Herbst DM , Reed AW , Cisar JS , Weber OD , Viader A , Alexander JP , Cunningham ML , Jones TK , Fraser IP , Grice CA , Ezekowitz RAB , O'Neill GP , Blankman JL
Ref : Journal of Pharmacology & Experimental Therapeutics , 367 :494 , 2018
Abstract :
PubMedSearch : Clapper_2018_J.Pharmacol.Exp.Ther_367_494
PubMedID: 30305428

Title : Carboxylesterase converts Amplex red to resorufin: Implications for mitochondrial H2O2 release assays - Miwa_2016_Free.Radic.Biol.Med_90_173
Author(s) : Miwa S , Treumann A , Bell A , Vistoli G , Nelson G , Hay S , von Zglinicki T
Ref : Free Radic Biol Med , 90 :173 , 2016
Abstract :
PubMedSearch : Miwa_2016_Free.Radic.Biol.Med_90_173
PubMedID: 26577176

Title : Inactivation of the Mycobacterium tuberculosis antigen 85 complex by covalent, allosteric inhibitors - Favrot_2014_J.Biol.Chem_289_25031
Author(s) : Favrot L , Lajiness DH , Ronning DR
Ref : Journal of Biological Chemistry , 289 :25031 , 2014
Abstract :
PubMedSearch : Favrot_2014_J.Biol.Chem_289_25031
PubMedID: 25028518
Gene_locus related to this paper: myctu-a85c

Title : Directed evolution of an esterase from Pseudomonas fluorescens. Random mutagenesis by error-prone PCR or a mutator strain and identification of mutants showing enhanced enantioselectivity by a resorufin-based fluorescence assay - Henke_1999_Biol.Chem_380_1029
Author(s) : Henke E , Bornscheuer UT
Ref : Biol Chem , 380 :1029 , 1999
Abstract :
PubMedSearch : Henke_1999_Biol.Chem_380_1029
PubMedID: 10494857
Gene_locus related to this paper: psefl-este

Title : Resorufin butyrate and indoxyl acetate as fluorogenic substrates for cholinesterase -
Author(s) : Guilbault GG , Kramer DN
Ref : Analytical Chemistry , 37 :120 , 1965
PubMedID: