Angiotensin-converting enzyme inhibitor

Some prodrugs are hydrolysed by carboxylesterases to give Angiotensin-converting enzyme inhibitors

Substrate	Main targeted enzyme families	Type
Fosinopril	Plasmodium_subtelomeric_PST-A Carb_B_Chordata	Not A\/B H target Drug Pro-Drug Pyrrolidine Angiotensin-converting enzyme inhibitor Organophosphate
Trandolapril	Carb_B_Chordata	Not A\/B H target Drug Pro-Drug Pyrrolidine Angiotensin-converting enzyme inhibitor
Enalapril	Carb_B_Chordata	Not A\/B H target Drug Pro-Drug Pyrrolidine Angiotensin-converting enzyme inhibitor
Quinapril	Carb_B_Chordata	Isoquinoline Not A\/B H target Drug Pro-Drug Angiotensin-converting enzyme inhibitor
Temocapril	Carb_B_Chordata	Not A\/B H target Pro-Drug Drug Angiotensin-converting enzyme inhibitor Azepane Thiophen