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Angiotensin-converting enzyme inhibitor

Some prodrugs are hydrolysed by carboxylesterases to give Angiotensin-converting enzyme inhibitors
Substrate Main targeted enzyme familyes Type Structure
Fosinopril Plasmodium_subtelomeric_PST-A Carb_B_Chordata Not A\/B H target Drug Pro-Drug Pyrrolidine Angiotensin-converting enzyme inhibitor Organophosphate
Trandolapril Carb_B_Chordata Not A\/B H target Drug Pro-Drug Pyrrolidine Angiotensin-converting enzyme inhibitor
Enalapril Carb_B_Chordata Not A\/B H target Drug Pro-Drug Pyrrolidine Angiotensin-converting enzyme inhibitor
Quinapril Carb_B_Chordata Isoquinoline Not A\/B H target Drug Pro-Drug Angiotensin-converting enzyme inhibitor
Temocapril Carb_B_Chordata Not A\/B H target Pro-Drug Drug Angiotensin-converting enzyme inhibitor Azepane