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lacla-pepx

Lactococcus lactis and Lactococcus lactis (subsp.cremoris)(Streptococcus cremoris)(and strains MG1363; SK11) X-prolyl dipeptidyl aminopeptidase (pepXP)

Comment

Belongs to peptidase family s15

Relationship

Family : Lactobacillus_peptidase

Block : X

Position in NCBI Life Tree : Lactobacillus lactis

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Bacteria N E > Terrabacteria group N E > Firmicutes N E > Bacilli N E > Lactobacillales N E > Lactobacillaceae N E > Lactobacillus N E > Lactobacillus delbrueckii N E > Lactobacillus delbrueckii subsp. lactis N E

Molecular evidence

No mutation

No kinetic

No disease

No inhibitor

Database

Sequence

Peptide

MRFNHFSIVD KNFDEQLAEL DQLGFRWSVF WDEKKILKDF LIQSPSDMTA LQATAELDVI EFLKSSIELD WEIFWNIALQ LLDFVPNFDF EIGKAFEYAK NSNLPQIEAE MTTENIISAF YYLLCTRRKT GMILVEHWVS EGLLPLDNHY HFFNDKSLAT FDSSLLEREV LWVESPVDSE QRGENDLIKI QIIRPKSTEK LPVVMTASPY HLGINDKAND LALHDMNVEL EEKTSHEIHV EQKLPQKLSA KAKELPIVDK APYRFTHGWT YSLNDYFLTR GFASIYVAGV GTRSSDGFQT SGDYQQIYSM TAVIDWLNGR ARAYTSRKKT HEIKASWANG KVAMTGKSYL GTMAYGAATT GVEGLELILA EAGISSWYNY YRENGLVRSP GGFPGEDLDV LAALTYSRNL DGADFLKGNA EYEKRLAEMT AALDRKSGDY NQFWHDRNYL INTDKVKADV LIVHGLQDWN VTPEQAYNFW KALPEGHAKH AFLHRGAHIY MNSWQSIDFS ETINAYFVAK LLDRDLNLNL PPVILQENSK DQVWTMMNDF GANTQIKLPL GKTAVSFAQF DNNYDDETFK KYSKDFNVFK KDLFENKANE AVIDLELPSM LTINGPVELE LRLKLNDTKG FLSAQILDFG QKKRLEDKVR VKDFKVLDRG RNFMLDDLVE LPLVESPYQL VTKGFTNLQN QSLLTVSDLK ADEWFTIKFE LQPTIYHLEK ADKLRVILYS TDFEHTVRDN RKVTYEIDLS QSKLIIPIES VKN

References (6)

Title : Complete genome sequence of the prototype lactic acid bacterium Lactococcus lactis subsp. cremoris MG1363 - Wegmann_2007_J.Bacteriol_189_3256
Author(s) : Wegmann U , O'Connell-Motherway M , Zomer A , Buist G , Shearman C , Canchaya C , Ventura M , Goesmann A , Gasson MJ , Kuipers OP , van Sinderen D , Kok J
Ref : Journal of Bacteriology , 189 :3256 , 2007
PubMedID: 17307855
Gene_locus related to this paper: lacla-cpo , lacla-pepx , laclk-d2bl62 , lacls-q02y15 , lacls-q030p2

Title : Comparative genomics of the lactic acid bacteria - Makarova_2006_Proc.Natl.Acad.Sci.U.S.A_103_15611
Author(s) : Makarova K , Slesarev A , Wolf Y , Sorokin A , Mirkin B , Koonin E , Pavlov A , Pavlova N , Karamychev V , Polouchine N , Shakhova V , Grigoriev I , Lou Y , Rohksar D , Lucas S , Huang K , Goodstein DM , Hawkins T , Plengvidhya V , Welker D , Hughes J , Goh Y , Benson A , Baldwin K , Lee JH , Diaz-Muniz I , Dosti B , Smeianov V , Wechter W , Barabote R , Lorca G , Altermann E , Barrangou R , Ganesan B , Xie Y , Rawsthorne H , Tamir D , Parker C , Breidt F , Broadbent J , Hutkins R , O'Sullivan D , Steele J , Unlu G , Saier M , Klaenhammer T , Richardson P , Kozyavkin S , Weimer B , Mills D
Ref : Proc Natl Acad Sci U S A , 103 :15611 , 2006
PubMedID: 17030793
Gene_locus related to this paper: 9laco-c0xef2 , lacba-pepx , lacba-q03pm4 , lacba-q03sl1 , lacc3-pepx , lacc3-q03b36 , lacc3-q033u9 , lacc3-q035l1 , lacc3-q036j3 , lacc3-q036j8 , laccb-b3wcx2 , lacda-q1g8l1 , lacdb-q04b33 , lacdb-q04bn2 , lacdb-q04ci8 , lacdb-q04cw3 , lacdl-pepx , lacdl-pip , lacga-q040j4 , lacga-q040j9 , lacga-q040s2 , lacga-q042h9 , lacga-q043a3 , lacga-q043m1 , lacga-q045l3 , lacga-q046w1 , lacga-q047a5 , lacjo-q74hh0 , lacjo-q74ii3 , lacla-pepx , laclk-d2bl62 , lacls-q02y15 , lacls-q030e4 , lacls-q030p2 , lacrh-pepr , leumc-c2kjv5 , leumm-q03x93 , leumm-q03y60 , leumm-q03y71 , leumm-q03z72 , oenob-q04d10 , oenob-q04f06 , oenob-q04f19 , oenob-q04fw8 , oenob-q04ga3 , oenob-q04h47 , oenoe-a0nif9 , oenoe-a0nl98 , oenoe-d3lb54 , pedpa-pepx , pedpa-q03gh4 , pedpa-q03h47 , pedpa-q03hj2 , strt1-q5lz16 , strt1-q5lza1 , strt2-q5m420 , strtr-pepx , oenoe-k6pl10 , lacba-pip , lacca-k0n1x0 , lacpa-s2ter8 , lacpa-s2rz88 , pedpa-q03hz6 , oenob-q04dp7

Title : The Structural Basis for Catalysis and Specificity of the X-Prolyl Dipeptidyl Aminopeptidase from Lactococcus lactis - Rigolet_2002_Structure.(Camb)_10_1383
Author(s) : Rigolet P , Mechin I , Delage M , Chich J
Ref : Structure (Camb) , 10 :1383 , 2002
PubMedID: 12377124
Gene_locus related to this paper: lacla-pepx

Title : The complete genome sequence of the lactic acid bacterium Lactococcus lactis ssp. lactis IL1403 - Bolotin_2001_Genome.Res_11_731
Author(s) : Bolotin A , Wincker P , Mauger S , Jaillon O , Malarme K , Weissenbach J , Ehrlich SD , Sorokin A
Ref : Genome Res , 11 :731 , 2001
PubMedID: 11337471
Gene_locus related to this paper: lacla-cpo , lacla-ESTA , lacla-menX , lacla-pepx , lacla-YAHD , lacla-YBCH , lacla-YEEB , lacla-YMGC , lacla-YNDB , lacla-YNEB , lacla-YQAG , lacla-YQBF , lacla-YRIC , lacla-YUFC

Title : Cloning and DNA sequence analysis of an X-prolyl Dipeptidyl aminopeptidase gene from Lactococcus lactis subsp. lactis NCDO 763 - Nardi_1991_Appl.Environ.Microbiol_57_45
Author(s) : Nardi M , Chopin M-C , Chopin A , Cals M-M , Gripon J-C
Ref : Applied Environmental Microbiology , 57 :45 , 1991
PubMedID: 1674656
Gene_locus related to this paper: lacla-pepx

Title : Molecular cloning and sequence analysis of the X-prolyl dipeptidyl aminopeptidase gene from Lactococcus lactis subsp. cremoris - Mayo_1991_Appl.Environ.Microbiol_57_38
Author(s) : Mayo B , Kok J , Venema K , Bockelmann W , Teuber M , Reinke H and
Ref : Applied Environmental Microbiology , 57 :38 , 1991
PubMedID: 1674655
Gene_locus related to this paper: lacla-pepx