Title : ASS234, As a New Multi-Target Directed Propargylamine for Alzheimer's Disease Therapy - Marco-Contelles_2016_Front.Neurosci_10_294 |
Author(s) : Marco-Contelles J , Unzeta M , Bolea I , Esteban G , Ramsay RR , Romero A , Martinez-Murillo R , Carreiras MC , Ismaili L |
Ref : Front Neurosci , 10 :294 , 2016 |
Abstract : |
PubMedSearch : Marco-Contelles_2016_Front.Neurosci_10_294 |
PubMedID: 27445665 |
Title : Multi-Target Directed Donepezil-Like Ligands for Alzheimer's Disease - Unzeta_2016_Front.Neurosci_10_205 |
Author(s) : Unzeta M , Esteban G , Bolea I , Fogel WA , Ramsay RR , Youdim MB , Tipton KF , Marco-Contelles J |
Ref : Front Neurosci , 10 :205 , 2016 |
Abstract : |
PubMedSearch : Unzeta_2016_Front.Neurosci_10_205 |
PubMedID: 27252617 |
Title : Design, synthesis, pharmacological evaluation, QSAR analysis, molecular modeling and ADMET of novel donepezil-indolyl hybrids as multipotent cholinesterase\/monoamine oxidase inhibitors for the potential treatment of Alzheimer's disease - Bautista-Aguilera_2014_Eur.J.Med.Chem_75C_82 |
Author(s) : Bautista-Aguilera OM , Esteban G , Bolea I , Nikolic K , Agbaba D , Moraleda I , Iriepa I , Samadi A , Soriano E , Unzeta M , Marco-Contelles J |
Ref : Eur Journal of Medicinal Chemistry , 75C :82 , 2014 |
Abstract : |
PubMedSearch : Bautista-Aguilera_2014_Eur.J.Med.Chem_75C_82 |
PubMedID: 24530494 |
Title : Propargylamine-derived multitarget-directed ligands: fighting Alzheimer's disease with monoamine oxidase inhibitors - Bolea_2013_J.Neural.Transm_120_893 |
Author(s) : Bolea I , Gella A , Unzeta M |
Ref : J Neural Transm , 120 :893 , 2013 |
Abstract : |
PubMedSearch : Bolea_2013_J.Neural.Transm_120_893 |
PubMedID: 23238976 |
Title : A therapeutic approach to cerebrovascular diseases based on indole substituted hydrazides and hydrazines able to interact with human vascular adhesion protein-1, monoamine oxidases (A and B), AChE and BCHE - Esteban_2013_J.Neural.Transm_120_911 |
Author(s) : Esteban G , Bolea I , Sun P , Sole M , Samadi A , Marco-Contelles J , Unzeta M |
Ref : J Neural Transm , 120 :911 , 2013 |
Abstract : |
PubMedSearch : Esteban_2013_J.Neural.Transm_120_911 |
PubMedID: 23263540 |
Title : Multipotent, permeable drug ASS234 inhibits Abeta aggregation, possesses antioxidant properties and protects from Abeta-induced apoptosis in vitro - Bolea_2013_Curr.Alzheimer.Res_10_797 |
Author(s) : Bolea I , Gella A , Monjas L , Perez C , Rodriguez-Franco MI , Marco-Contelles J , Samadi A , Unzeta M |
Ref : Curr Alzheimer Res , 10 :797 , 2013 |
Abstract : |
PubMedSearch : Bolea_2013_Curr.Alzheimer.Res_10_797 |
PubMedID: 23919774 |
Title : Multipotent MAO and cholinesterase inhibitors for the treatment of Alzheimer's disease: synthesis, pharmacological analysis and molecular modeling of heterocyclic substituted alkyl and cycloalkyl propargyl amine - Samadi_2012_Eur.J.Med.Chem_52_251 |
Author(s) : Samadi A , de los Rios C , Bolea I , Chioua M , Iriepa I , Moraleda I , Bartolini M , Andrisano V , Galvez E , Valderas C , Unzeta M , Marco-Contelles J |
Ref : Eur Journal of Medicinal Chemistry , 52 :251 , 2012 |
Abstract : |
PubMedSearch : Samadi_2012_Eur.J.Med.Chem_52_251 |
PubMedID: 22503231 |
Title : Synthesis, biological evaluation, and molecular modeling of donepezil and N-[(5-(benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine hybrids as new multipotent cholinesterase\/monoamine oxidase inhibitors for the treatment of Alzheimer's disease - Bolea_2011_J.Med.Chem_54_8251 |
Author(s) : Bolea I , Juarez-Jimenez J , de los Rios C , Chioua M , Pouplana R , Luque FJ , Unzeta M , Marco-Contelles J , Samadi A |
Ref : Journal of Medicinal Chemistry , 54 :8251 , 2011 |
Abstract : |
PubMedSearch : Bolea_2011_J.Med.Chem_54_8251 |
PubMedID: 22023459 |
Title : Synthesis, biological assessment and molecular modeling of new multipotent MAO and cholinesterase inhibitors as potential drugs for the treatment of Alzheimer's disease - Samadi_2011_Eur.J.Med.Chem_46_4665 |
Author(s) : Samadi A , Chioua M , Bolea I , de los Rios C , Iriepa I , Moraleda I , Bastida A , Esteban G , Unzeta M , Galvez E , Marco-Contelles J |
Ref : Eur Journal of Medicinal Chemistry , 46 :4665 , 2011 |
Abstract : |
PubMedSearch : Samadi_2011_Eur.J.Med.Chem_46_4665 |
PubMedID: 21669479 |