mouse-Ces1c

Mus musculus mRNA for carboxylesterase, Ces1c lung surfactant convertase, Liver carboxylesterase N, PES-N clone MGC:18575

Comment

replaces mouse-cxest, mouse-sfest, mouse-cxestb

Relationship

Family : Carb_B_Chordata

Block : C

Position in NCBI Life Tree : Mus musculus

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Deuterostomia N E > Chordata N E > Craniata N E > Vertebrata N E > Gnathostomata N E > Teleostomi N E > Euteleostomi N E > Sarcopterygii N E > Dipnotetrapodomorpha N E > Tetrapoda N E > Amniota N E > Mammalia N E > Theria N E > Eutheria N E > Boreoeutheria N E > Euarchontoglires N E > Glires N E > Rodentia N E > Myomorpha N E > Muroidea N E > Muridae N E > Murinae N E > Mus [genus] N E > Mus [subgenus] N E > Mus musculus N E

Molecular evidence

No mutation

No structure

No kinetic

No disease

Sequence

Peptide

MWLHVLVWAS LAVCPILGHS LLPPVVDTTQ GKVLGKYISL EGFEQPVAVF LGVPFAKPPL GSLRFAPPQP AEPWSFVKNA TSYPPMCSQD AGWAKILSDM FSTEKEILPL KISEDCLYLN IYSPADLTKS SQLPVMVWIH GGGLVIGGRS PYNGLALSAH ENVVVVTIQY RLGIWGLFST GDEHSQGNWA HLDQLAALRW VQDNIANFGG NPDSVTIFGE SSGGISVSVL VLSPLGKDLF HRAISESGVV INTNVGKKNI QAVNEIIATL SQCNDTSSAA MVQCLRQKTE SELLEISGKL VQYNISLSTV IDGVVLPKAP EEILAEKSFN TVPYIVGFNK QEFGWIIPMM LQNLLPEGKM NEETASLLLR RFHSELNISE SMIPAVIEKY LRGVDDPAKK SELILDMFGD IFFGIPAVLM SRSLRDAGVS TYMYEFRYRP SFVSDKRPQM VEGDHGDEIF SVFGAPLLKE GASEEETNLS KMVMKFWANF ARNGNPNGEG LPHWPEYDEK EGYLQIGATT QQAQRLKAEE VAFWTELPAK NPPETDPTEH TEHK

References (19)

Title : Carboxylesterase 1 family knockout alters drug disposition and lipid metabolism - Gan_2023_Acta.Pharm.Sin.B_13_618
Author(s) : Gan C , Wang J , Martinez-Chavez A , Hillebrand M , de Vries N , Beukers J , Wagenaar E , Wang Y , Lebre MC , Rosing H , Klarenbeek S , Ali RB , Pritchard C , Huijbers I , Beijnen JH , Schinkel AH
Ref : Acta Pharm Sin B , 13 :618 , 2023
PubMedID: 36873183
Gene_locus related to this paper: mouse-Ces1a , mouse-Ces1b , mouse-Ces1c , mouse-Ces1d , mouse-Ces1e , mouse-Ces1f , mouse-Ces1g , mouse-Ces1h

Title : Natural deletion of mouse carboxylesterases Ces1c\/d\/e impacts drug metabolism and metabolic syndrome development - Gan_2023_Biomed.Pharmacother_164_114956
Author(s) : Gan C , Wang J , Wang Y , Martinez-Chavez A , Hillebrand M , de Vries N , Beukers J , Lebre MC , Wagenaar E , Rosing H , Klarenbeek S , Bleijerveld OB , Song JY , Altelaar M , Beijnen JH , Schinkel AH
Ref : Biomed Pharmacother , 164 :114956 , 2023
PubMedID: 37267638
Gene_locus related to this paper: human-CES1 , mouse-Ces1c , mouse-Ces1d , mouse-Ces1e

Title : Hydrolysis of dibutyl phthalate and di(2-ethylhexyl) phthalate in human liver, small intestine, kidney, and lung: An in vitro analysis using organ subcellular fractions and recombinant carboxylesterases - Isobe_2023_Chem.Biol.Interact_372_110353
Author(s) : Isobe T , Ohkawara S , Mori Y , Jinno H , Tanaka-Kagawa T , Hanioka N
Ref : Chemico-Biological Interactions , 372 :110353 , 2023
PubMedID: 36657734
Gene_locus related to this paper: human-CES1 , mouse-Ces1c

Title : Integrative systems analysis identifies genetic and dietary modulators of bile acid homeostasis - Li_2022_Cell.Metab__
Author(s) : Li H , Perino A , Huang Q , Von Alvensleben GVG , Banaei-Esfahani A , Velazquez-Villegas LA , Gariani K , Korbelius M , Bou Sleiman M , Imbach J , Sun Y , Li X , Bachmann A , Goeminne LJE , Gallart-Ayala H , Williams EG , Ivanisevic J , Auwerx J , Schoonjans K
Ref : Cell Metab , : , 2022
PubMedID: 36099916
Gene_locus related to this paper: mouse-Ces1c

Title : Assessments of the In Vitro and In Vivo Linker Stability and Catabolic Fate for the Ortho Hydroxy-Protected Aryl Sulfate Linker by Immuno-Affinity Capture Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometric Assay - Lee_2021_Pharmaceutics_13_
Author(s) : Lee BI , Park SJ , Park Y , Shin SH , Choi JM , Park MJ , Lim JH , Kim SY , Lee H , Shin YG
Ref : Pharmaceutics , 13 : , 2021
PubMedID: 33478046
Gene_locus related to this paper: mouse-Ces1c

Title : Delayed midazolam dose effects against soman in male and female plasma carboxylesterase knockout mice - Kundrick_2020_Ann.N.Y.Acad.Sci__
Author(s) : Kundrick E , Marrero-Rosado B , Stone M , Schultz C , Walker K , Lee-Stubbs RB , de Araujo Furtado M , Lumley LA
Ref : Annals of the New York Academy of Sciences , : , 2020
PubMedID: 32027397
Gene_locus related to this paper: mouse-Ces1c

Title : Unraveling the Interaction between Carboxylesterase 1c and the Antibody-Drug Conjugate SYD985: Improved Translational PK\/PD by Using Ces1c Knockout Mice - Ubink_2018_Mol.Cancer.Ther_17_2389
Author(s) : Ubink R , Dirksen EHC , Rouwette M , Bos ES , Janssen I , Egging DF , Loosveld EM , van Achterberg TA , Berentsen K , van der Lee MMC , Bichat F , Raguin O , van der Vleuten MAJ , Groothuis PG , Dokter WHA
Ref : Mol Cancer Ther , 17 :2389 , 2018
PubMedID: 30093567
Gene_locus related to this paper: mouse-Ces1c

Title : Soman-induced status epilepticus, epileptogenesis, and neuropathology in carboxylesterase knockout mice treated with midazolam - Marrero-Rosado_2018_Epilepsia_59_2206
Author(s) : Marrero-Rosado B , de Araujo Furtado M , Schultz CR , Stone M , Kundrick E , Walker K , O'Brien S , Du F , Lumley LA
Ref : Epilepsia , 59 :2206 , 2018
PubMedID: 30368799
Gene_locus related to this paper: mouse-Ces1c

Title : Hepatic carboxylesterase 1 is induced by glucose and regulates postprandial glucose levels - Xu_2014_PLoS.One_9_e109663
Author(s) : Xu J , Yin L , Xu Y , Li Y , Zalzala M , Cheng G , Zhang Y
Ref : PLoS ONE , 9 :e109663 , 2014
PubMedID: 25285996
Gene_locus related to this paper: mouse-Ces1c

Title : Deficiency of carboxylesterase 1\/esterase-x results in obesity, hepatic steatosis, and hyperlipidemia - Quiroga_2012_Hepatology_56_2188
Author(s) : Quiroga AD , Li L , Trotzmuller M , Nelson R , Proctor SD , Kofeler H , Lehner R
Ref : Hepatology , 56 :2188 , 2012
PubMedID: 22806626
Gene_locus related to this paper: mouse-Ces1c , mouse-Ces1g

Title : Production of ES1 plasma carboxylesterase knockout mice for toxicity studies - Duysen_2011_Chem.Res.Toxicol_24_1891
Author(s) : Duysen EG , Koentgen F , Williams GR , Timperley CM , Schopfer LM , Cerasoli DM , Lockridge O
Ref : Chemical Research in Toxicology , 24 :1891 , 2011
PubMedID: 21875074
Gene_locus related to this paper: mouse-Ces1c

Title : Es-x\/Ces1 prevents triacylglycerol accumulation in McArdle-RH7777 hepatocytes - Ko_2009_Biochim.Biophys.Acta_1791_1133
Author(s) : Ko KW , Erickson B , Lehner R
Ref : Biochimica & Biophysica Acta , 1791 :1133 , 2009
PubMedID: 19651238
Gene_locus related to this paper: mouse-Ces1c

Title : Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides - Bernhard_2007_J.Proteome.Res_6_987
Author(s) : Bernhard OK , Kapp EA , Simpson RJ
Ref : J Proteome Res , 6 :987 , 2007
PubMedID: 17330941
Gene_locus related to this paper: mouse-Ces1c

Title : Proteome-wide characterization of N-glycosylation events by diagonal chromatography - Ghesquiere_2006_J.Proteome.Res_5_2438
Author(s) : Ghesquiere B , Van Damme J , Martens L , Vandekerckhove J , Gevaert K
Ref : J Proteome Res , 5 :2438 , 2006
PubMedID: 16944957
Gene_locus related to this paper: mouse-Ces1c

Title : Molecular cloning, characterization, and differential expression pattern of mouse lung surfactant convertase - Krishnasamy_1998_Am.J.Physiol_275_L969
Author(s) : Krishnasamy S , Teng AL , Dhand R , Schultz RM , Gross NJ
Ref : American Journal of Physiology , 275 :L969 , 1998
PubMedID: 9815115
Gene_locus related to this paper: mouse-Ces1c

Title : Lung surfactant convertase is a member of the carboxylesterase family - Krishnasamy_1997_Biochem.Biophys.Res.Commun_235_180
Author(s) : Krishnasamy S , Gross NJ , Teng AL , Schultz RM , Dhand R
Ref : Biochemical & Biophysical Research Communications , 235 :180 , 1997
PubMedID: 9196059
Gene_locus related to this paper: mouse-Ces1c

Title : Characterization of a murine cDNA encoding a member of the carboxylesterase multigene family - Ovnic_1991_Genomics_9_344
Author(s) : Ovnic M , Tepperman K , Medda S , Elliott RW , Stephenson DA , Grant SG , Ganschow RE
Ref : Genomics , 9 :344 , 1991
PubMedID: 1840565
Gene_locus related to this paper: mouse-Ces1c

Title : cDNA cloning of esterase 1, the major esterase activity in mouse plasma - Genetta_1988_Biochem.Biophys.Res.Commun_151_1364
Author(s) : Genetta TL , D'Eustachio P , Kadner SS , Finlay TH
Ref : Biochemical & Biophysical Research Communications , 151 :1364 , 1988
PubMedID: 2895647
Gene_locus related to this paper: mouse-Ces1c