| Title : Rational mutagenesis of an epoxide hydrolase and its structural mechanism for the enantioselectivity improvement toward chiral ortho-fluorostyrene oxide - Lu_2024_Int.J.Biol.Macromol_282_136864 |
| Author(s) : Lu ZY , Liao X , Jing WW , Liu KK , Ren QG , He YC , Hu D |
| Ref : Int J Biol Macromol , 282 :136864 , 2024 |
| Abstract : |
| PubMedSearch : Lu_2024_Int.J.Biol.Macromol_282_136864 |
| PubMedID: 39476898 |
| Gene_locus related to this paper: aspng-q1ktb5 |
| Title : Corrigendum to Design, synthesis and biological evaluation of carbamate derivatives incorporating multifunctional carrier scaffolds as pseudo-irreversible cholinesterase inhibitors for the treatment of Alzheimer's disease [Eur. J. Med. Chem. 265 (2024) 116071] - |
| Author(s) : Liu Y , Ma C , Li Y , Li M , Cui T , Zhao X , Li Z , Jia H , Wang H , Xiu X , Hu D , Zhang R , Wang N , Liu P , Yang H , Cheng M |
| Ref : Eur Journal of Medicinal Chemistry , :116169 , 2024 |
| PubMedID: 38290915 |
| Title : Engineering an Epoxide Hydrolase for Chemoenzymatic Asymmetric Synthesis of Chiral Triazole Fungicide (S)- and (R)-Flutriafol - Hu_2024_J.Agric.Food.Chem__ |
| Author(s) : Hu D , Lu ZY , Liao X , Jia XW , Song WH , Hu YY , He YC |
| Ref : Journal of Agricultural and Food Chemistry , : , 2024 |
| Abstract : |
| PubMedSearch : Hu_2024_J.Agric.Food.Chem__ |
| PubMedID: 39297229 |
| Gene_locus related to this paper: rhodp-EPH1 |
| Title : Chemoenzymatic Asymmetric Synthesis of Chiral Triazole Fungicide (R)-Tebuconazole in High Optical Purity Mediated by an Epoxide Hydrolase from Rhodotorula paludigensis - Hu_2024_J.Agric.Food.Chem_72_10428 |
| Author(s) : Hu D , Jia XW , Lu JL , Lu ZY , Tang CD , Xue F , Huang C , Ren QG , He YC |
| Ref : Journal of Agricultural and Food Chemistry , 72 :10428 , 2024 |
| Abstract : |
| PubMedSearch : Hu_2024_J.Agric.Food.Chem_72_10428 |
| PubMedID: 38660720 |
| Gene_locus related to this paper: rhodp-EPH1 |
| Title : Artificial Intelligence Aided Lipase Production and Engineering for Enzymatic Performance Improvement - Ge_2023_J.Agric.Food.Chem__ |
| Author(s) : Ge F , Chen G , Qian M , Xu C , Liu J , Cao J , Li X , Hu D , Xu Y , Xin Y , Wang D , Zhou J , Shi H , Tan Z |
| Ref : Journal of Agricultural and Food Chemistry , : , 2023 |
| Abstract : |
| PubMedSearch : Ge_2023_J.Agric.Food.Chem__ |
| PubMedID: 37800676 |
| Title : Green biosynthesis of DHA-phospholipids in tailor-made supersaturated DHA aqueous solution and catalytic mechanism study - Zhang_2023_Food.Chem_431_137164 |
| Author(s) : Zhang T , Wang J , Zhao Y , Wang Z , Hu D , Liu Y , Zhang X , Li H , Zhao B , Li B |
| Ref : Food Chem , 431 :137164 , 2023 |
| Abstract : |
| PubMedSearch : Zhang_2023_Food.Chem_431_137164 |
| PubMedID: 37607420 |
| Title : Characterization of Sulfoxaflor and Its Metabolites on Survival, Growth, Reproduction, Biochemical Markers, and Transcription of Genes of Daphnia magna - Yuan_2023_J.Agric.Food.Chem__ |
| Author(s) : Yuan T , Jiao H , Ai L , Chen Y , Hu D , Lu P |
| Ref : Journal of Agricultural and Food Chemistry , : , 2023 |
| Abstract : |
| PubMedSearch : Yuan_2023_J.Agric.Food.Chem__ |
| PubMedID: 37070642 |
| Title : Green biosynthesis of rare DHA-phospholipids by lipase-catalyzed transesterification with edible algal oil in solvent-free system and catalytic mechanism study - Zhang_2023_Front.Bioeng.Biotechnol_11_1158348 |
| Author(s) : Zhang T , Li B , Wang Z , Hu D , Zhang X , Zhao B , Wang J |
| Ref : Front Bioeng Biotechnol , 11 :1158348 , 2023 |
| Abstract : |
| PubMedSearch : Zhang_2023_Front.Bioeng.Biotechnol_11_1158348 |
| PubMedID: 37064237 |
| Title : Design, synthesis and biological evaluation of carbamate derivatives incorporating multifunctional carrier scaffolds as pseudo-irreversible cholinesterase inhibitors for the treatment of Alzheimer's disease - Liu_2023_Eur.J.Med.Chem_265_116071 |
| Author(s) : Liu Y , Ma C , Li Y , Li M , Cui T , Zhao X , Li Z , Jia H , Wang H , Xiu X , Hu D , Zhang R , Wang N , Liu P , Yang H , Cheng M |
| Ref : Eur Journal of Medicinal Chemistry , 265 :116071 , 2023 |
| Abstract : |
| PubMedSearch : Liu_2023_Eur.J.Med.Chem_265_116071 |
| PubMedID: 38157596 |
| Title : Application of Marine Natural Products against Alzheimer's Disease: Past, Present and Future - Hu_2023_Mar.Drugs_21_ |
| Author(s) : Hu D , Jin Y , Hou X , Zhu Y , Chen D , Tai J , Chen Q , Shi C , Ye J , Wu M , Zhang H , Lu Y |
| Ref : Mar Drugs , 21 : , 2023 |
| Abstract : |
| PubMedSearch : Hu_2023_Mar.Drugs_21_ |
| PubMedID: 36662216 |
| Title : Biological Properties and Clinical Significance of Lipoprotein-Associated Phospholipase A(2) in Ischemic Stroke - Zhang_2022_Cardiovasc.Ther_2022_3328574 |
| Author(s) : Zhang S , Huang S , Hu D , Jiang F , Lv Y , Liu G |
| Ref : Cardiovasc Ther , 2022 :3328574 , 2022 |
| Abstract : |
| PubMedSearch : Zhang_2022_Cardiovasc.Ther_2022_3328574 |
| PubMedID: 36313479 |
| Gene_locus related to this paper: human-PLA2G7 |
| Title : Enantioselective bioaccumulation and toxicity of rac-sulfoxaflor in zebrafish (Danio rerio) - Deng_2022_Sci.Total.Environ_817_153007 |
| Author(s) : Deng Y , Wang R , Song B , Yang Y , Hu D , Xiao X , Chen X , Lu P |
| Ref : Sci Total Environ , 817 :153007 , 2022 |
| Abstract : |
| PubMedSearch : Deng_2022_Sci.Total.Environ_817_153007 |
| PubMedID: 35026276 |
| Title : Synthesis, insecticidal activity, and mode of action of novel imidazopyridine mesoionic derivatives containing an amido group - Liu_2022_Pest.Manag.Sci__ |
| Author(s) : Liu Z , Song R , Zhang D , Wu R , Liu T , Wu Z , Zhang J , Hu D |
| Ref : Pest Manag Sci , : , 2022 |
| Abstract : |
| PubMedSearch : Liu_2022_Pest.Manag.Sci__ |
| PubMedID: 36054072 |
| Title : Structure-Guided Regulation in the Enantioselectivity of an Epoxide Hydrolase to Produce Enantiomeric Monosubstituted Epoxides and Vicinal Diols via Kinetic Resolution - Hu_2022_Org.Lett__ |
| Author(s) : Hu D , Hu BC , Hou XD , Zhang D , Lei YQ , Rao YJ , Wu MC |
| Ref : Org Lett , : , 2022 |
| Abstract : |
| PubMedSearch : Hu_2022_Org.Lett__ |
| PubMedID: 35229602 |
| Gene_locus related to this paper: aspng-q1ktb5 |
| Title : NLRP1 variant M1184V decreases inflammasome activation in the context of DPP9 inhibition and asthma severity - Moecking_2021_J.Allergy.Clin.Immunol_147_2134 |
| Author(s) : Moecking J , Laohamonthonkul P , Chalker K , White MJ , Harapas CR , Yu CH , Davidson S , Hrovat-Schaale K , Hu D , Eng C , Huntsman S , Calleja DJ , Horvat JC , Hansbro PM , O'Donoghue RJJ , Ting JP , Burchard EG , Geyer M , Gerlic M , Masters SL |
| Ref : J Allergy Clin Immunol , 147 :2134 , 2021 |
| Abstract : |
| PubMedSearch : Moecking_2021_J.Allergy.Clin.Immunol_147_2134 |
| PubMedID: 33378691 |
| Title : Structure-guided improvement in the enantioselectivity of an Aspergillus usamii epoxide hydrolase for the gram-scale kinetic resolution of ortho-trifluoromethyl styrene oxide - Wen_2021_Enzyme.Microb.Technol_146_109778 |
| Author(s) : Wen Z , Hu D , Hu BC , Zhang D , Huang JF , Wu MC |
| Ref : Enzyme Microb Technol , 146 :109778 , 2021 |
| Abstract : |
| PubMedSearch : Wen_2021_Enzyme.Microb.Technol_146_109778 |
| PubMedID: 33812566 |
| Gene_locus related to this paper: aspng-q1ktb5 |
| Title : Nearly perfect kinetic resolution of racemic o-nitrostyrene oxide by AuEH2, a microsomal epoxide hydrolase from Aspergillus usamii, with high enantio- and regio-selectivity - Hu_2021_Int.J.Biol.Macromol_169_1 |
| Author(s) : Hu D , Hu BC , Wen Z , Zhang D , Liu YY , Zang J , Wu MC |
| Ref : Int J Biol Macromol , 169 :1 , 2021 |
| Abstract : |
| PubMedSearch : Hu_2021_Int.J.Biol.Macromol_169_1 |
| PubMedID: 33316339 |
| Gene_locus related to this paper: aspng-q1ktb5 |
| Title : The enantioselective toxicity and oxidative stress of dinotefuran on zebrafish (Danio rerio) - Ran_2021_Ecotoxicol.Environ.Saf_226_112809 |
| Author(s) : Ran L , Yang Y , Zhou X , Jiang X , Hu D , Lu P |
| Ref : Ecotoxicology & Environmental Safety , 226 :112809 , 2021 |
| Abstract : |
| PubMedSearch : Ran_2021_Ecotoxicol.Environ.Saf_226_112809 |
| PubMedID: 34592523 |
| Title : Greatly enhancing the enantioselectivity of PvEH2, a Phaseolus vulgaris epoxide hydrolase, towards racemic 1,2-epoxyhexane via replacing its partial cap-loop - Li_2020_Int.J.Biol.Macromol_156_225 |
| Author(s) : Li C , Hu BC , Wen Z , Hu D , Liu YY , Chu Q , Wu MC |
| Ref : Int J Biol Macromol , 156 :225 , 2020 |
| Abstract : |
| PubMedSearch : Li_2020_Int.J.Biol.Macromol_156_225 |
| PubMedID: 32294502 |
| Gene_locus related to this paper: phavu-v7bpm3 |
| Title : Manipulating regioselectivity of an epoxide hydrolase for single enzymatic synthesis of (R)-1,2-diols from racemic epoxides - Hu_2020_Chem.Commun.(Camb)__ |
| Author(s) : Hu D , Zong XC , Xue F , Li C , Hu BC , Wu MC |
| Ref : Chem Commun (Camb) , : , 2020 |
| Abstract : |
| PubMedSearch : Hu_2020_Chem.Commun.(Camb)__ |
| PubMedID: 32030396 |
| Title : Near-perfect kinetic resolution of racemic p-chlorostyrene oxide by SlEH1, a novel epoxide hydrolase from Solanum lycopersicum with extremely high enantioselectivity - Hu_2020_Int.J.Biol.Macromol_147_1213 |
| Author(s) : Hu BC , Hu D , Li C , Xu XF , Wen Z , Wu MC |
| Ref : Int J Biol Macromol , 147 :1213 , 2020 |
| Abstract : |
| PubMedSearch : Hu_2020_Int.J.Biol.Macromol_147_1213 |
| PubMedID: 31739010 |
| Gene_locus related to this paper: aspng-q1ktb5 |
| Title : Near-perfect kinetic resolution of o-methylphenyl glycidyl ether by RpEH, a novel epoxide hydrolase from Rhodotorula paludigena JNU001 with high stereoselectivity - Xu_2020_Appl.Microbiol.Biotechnol__ |
| Author(s) : Xu XF , Hu D , Hu BC , Li C , Liu YY , Wu MC |
| Ref : Applied Microbiology & Biotechnology , : , 2020 |
| Abstract : |
| PubMedSearch : Xu_2020_Appl.Microbiol.Biotechnol__ |
| PubMedID: 32462245 |
| Gene_locus related to this paper: rhodp-EPH1 |
| Title : N-methoxy-beta-carboline alkaloids with inhibitory activities against Abeta42 aggregation and acetylcholinesterase from the stems of Picrasma quassioides - Zhang_2020_Bioorg.Chem_101_104043 |
| Author(s) : Zhang J , Zhao SS , Xie J , Yang J , Chen GD , Hu D , Zhang WG , Wang CX , Yao XS , Gao H |
| Ref : Bioorg Chem , 101 :104043 , 2020 |
| Abstract : |
| PubMedSearch : Zhang_2020_Bioorg.Chem_101_104043 |
| PubMedID: 32629286 |
| Title : Improving the activity and enantioselectivity of PvEH1, a Phaseolus vulgaris epoxide hydrolase, for o-methylphenyl glycidyl ether by multiple site-directed mutagenesis on the basis of rational design - Li_2019_Mol.Catal_476_110517 |
| Author(s) : Li C , Kan T-T , Hu D , Wang T-T , Su Y-J , Zhang C , Cheng J-Q , Wu M-C |
| Ref : Molecular Catalysis , 476 :110517 , 2019 |
| Abstract : |
| PubMedSearch : Li_2019_Mol.Catal_476_110517 |
| PubMedID: |
| Gene_locus related to this paper: phavu-PvEH1 |
| Title : Substantially improving the enantioconvergence of PvEH1, a Phaseolus vulgaris epoxide hydrolase, towards m-chlorostyrene oxide by laboratory evolution - Zong_2019_Microb.Cell.Fact_18_202 |
| Author(s) : Zong XC , Li C , Xu YH , Hu D , Hu BC , Zang J , Wu MC |
| Ref : Microb Cell Fact , 18 :202 , 2019 |
| Abstract : |
| PubMedSearch : Zong_2019_Microb.Cell.Fact_18_202 |
| PubMedID: 31739786 |
| Gene_locus related to this paper: phavu-PvEH1 |
| Title : Multiple site-directed mutagenesis of a Phaseolus vulgaris epoxide hydrolase to improve its catalytic performance towards p-chlorostyrene oxide based on the computer-aided re-design - Li_2019_Int.J.Biol.Macromol_121_326 |
| Author(s) : Li C , Zhao J , Hu D , Hu BC , Wang R , Zang J , Wu MC |
| Ref : Int J Biol Macromol , 121 :326 , 2019 |
| Abstract : |
| PubMedSearch : Li_2019_Int.J.Biol.Macromol_121_326 |
| PubMedID: 30308283 |
| Gene_locus related to this paper: phavu-PvEH3 |
| Title : New phthalide derivatives from the Biscogniauxia sp. and their activities - Liu_2019_Fitoterapia__104184 |
| Author(s) : Liu YY , Zhao H , Xie J , Zou J , Hu D , Guo LD , Chen GD , Yao XS , Gao H |
| Ref : Fitoterapia , :104184 , 2019 |
| Abstract : |
| PubMedSearch : Liu_2019_Fitoterapia__104184 |
| PubMedID: 31145983 |
| Title : Stereoselective Hydrolysis of Epoxides by reVrEH3, a Novel Vigna radiata Epoxide Hydrolase with High Enantioselectivity or High and Complementary Regioselectivity - Hu_2017_J.Agric.Food.Chem_65_9861 |
| Author(s) : Hu D , Tang C , Li C , Kan T , Shi X , Feng L , Wu M |
| Ref : Journal of Agricultural and Food Chemistry , 65 :9861 , 2017 |
| Abstract : |
| PubMedSearch : Hu_2017_J.Agric.Food.Chem_65_9861 |
| PubMedID: 29058432 |
| Gene_locus related to this paper: vigra-Vreh3 |
| Title : Enantioconvergent hydrolysis of racemic styrene oxide at high concentration by a pair of novel epoxide hydrolases into (R)-phenyl-1,2-ethanediol - Wang_2017_Biotechnol.Lett_39_1917 |
| Author(s) : Wang R , Hu D , Zong X , Li J , Ding L , Wu M |
| Ref : Biotechnol Lett , 39 :1917 , 2017 |
| Abstract : |
| PubMedSearch : Wang_2017_Biotechnol.Lett_39_1917 |
| PubMedID: 28875350 |
| Gene_locus related to this paper: vigra-Vreh3 , aspng-q1ktb5 |
| Title : Three New Ergot Alkaloids from the Fruiting Bodies of Xylaria nigripes (Kl.) Sacc - Hu_2017_Chem.Biodivers_14_ |
| Author(s) : Hu D , Li M |
| Ref : Chem Biodivers , 14 : , 2017 |
| Abstract : |
| PubMedSearch : Hu_2017_Chem.Biodivers_14_ |
| PubMedID: 27448231 |
| Title : Directed modification of a novel epoxide hydrolase from Phaseolus vulgaris to improve its enantioconvergence towards styrene epoxides - Ye_2016_Catal.Commun_87_32 |
| Author(s) : Ye HH , Hu D , Shi XL , Wu MC , Deng C , Li JF |
| Ref : Catalysis Communications , 87 :32 , 2016 |
| Abstract : |
| PubMedSearch : Ye_2016_Catal.Commun_87_32 |
| PubMedID: |
| Gene_locus related to this paper: phavu-PvEH1 |
| Title : Kinetic resolution of racemic styrene oxide at a high concentration by recombinant Aspergillus usamii epoxide hydrolase in an n-hexanol\/buffer biphasic system - Hu_2016_J.Biotechnol_236_152 |
| Author(s) : Hu D , Wang R , Shi XL , Ye HH , Wu Q , Wu MC , Chu JJ |
| Ref : J Biotechnol , 236 :152 , 2016 |
| Abstract : |
| PubMedSearch : Hu_2016_J.Biotechnol_236_152 |
| PubMedID: 27546798 |
| Gene_locus related to this paper: aspng-q1ktb5 |
| Title : Biosynthesis of LL-Z1272beta: Discovery of a New Member of NRPS-like Enzymes for Aryl-Aldehyde Formation - Li_2016_Chembiochem_17_904 |
| Author(s) : Li C , Matsuda Y , Gao H , Hu D , Yao XS , Abe I |
| Ref : Chembiochem , 17 :904 , 2016 |
| Abstract : |
| PubMedSearch : Li_2016_Chembiochem_17_904 |
| PubMedID: 26972702 |
| Gene_locus related to this paper: stabi-stba |
| Title : Expression of a novel epoxide hydrolase of Aspergillus usamii E001 in Escherichia coli and its performance in resolution of racemic styrene oxide - Hu_2015_J.Ind.Microbiol.Biotechnol_42_671 |
| Author(s) : Hu D , Tang CD , Yang B , Liu JC , Yu T , Deng C , Wu MC |
| Ref : J Ind Microbiol Biotechnol , 42 :671 , 2015 |
| Abstract : |
| PubMedSearch : Hu_2015_J.Ind.Microbiol.Biotechnol_42_671 |
| PubMedID: 25733186 |
| Gene_locus related to this paper: aspng-q1ktb5 |
| Title : Improvement in the thermostability of a type A feruloyl esterase, AuFaeA, from Aspergillus usamii by iterative saturation mutagenesis - Yin_2015_Appl.Microbiol.Biotechnol_99_10047 |
| Author(s) : Yin X , Li JF , Wang CJ , Hu D , Wu Q , Gu Y , Wu MC |
| Ref : Applied Microbiology & Biotechnology , 99 :10047 , 2015 |
| Abstract : |
| PubMedSearch : Yin_2015_Appl.Microbiol.Biotechnol_99_10047 |
| PubMedID: 26266754 |
| Gene_locus related to this paper: aspni-FAEA |
| Title : Contribution of Disulfide Bridges to the Thermostability of a Type A Feruloyl Esterase from Aspergillus usamii - Yin_2015_PLoS.One_10_e0126864 |
| Author(s) : Yin X , Hu D , Li JF , He Y , Zhu TD , Wu MC |
| Ref : PLoS ONE , 10 :e0126864 , 2015 |
| Abstract : |
| PubMedSearch : Yin_2015_PLoS.One_10_e0126864 |
| PubMedID: 25969986 |
| Gene_locus related to this paper: aspni-FAEA |
| Title : Specific adaptation of Ustilaginoidea virens in occupying host florets revealed by comparative and functional genomics - Zhang_2014_Nat.Commun_5_3849 |
| Author(s) : Zhang Y , Zhang K , Fang A , Han Y , Yang J , Xue M , Bao J , Hu D , Zhou B , Sun X , Li S , Wen M , Yao N , Ma LJ , Liu Y , Zhang M , Huang F , Luo C , Zhou L , Li J , Chen Z , Miao J , Wang S , Lai J , Xu JR , Hsiang T , Peng YL , Sun W |
| Ref : Nat Commun , 5 :3849 , 2014 |
| Abstract : |
| PubMedSearch : Zhang_2014_Nat.Commun_5_3849 |
| PubMedID: 24846013 |
| Gene_locus related to this paper: ustvr-a0a063bxn3 |
| Title : Design, synthesis and biological evaluation of novel dual inhibitors of acetylcholinesterase and beta-secretase - Zhu_2009_Bioorg.Med.Chem_17_1600 |
| Author(s) : Zhu Y , Xiao K , Ma L , Xiong B , Fu Y , Yu H , Wang W , Wang X , Hu D , Peng H , Li J , Gong Q , Chai Q , Tang X , Zhang H , Shen J |
| Ref : Bioorganic & Medicinal Chemistry , 17 :1600 , 2009 |
| Abstract : |
| PubMedSearch : Zhu_2009_Bioorg.Med.Chem_17_1600 |
| PubMedID: 19162488 |