Zorbaz T

General

Full name : Zorbaz Tamara

First name : Tamara

Mail : Institute for Medical Research and Occupational Health, Ksaverska cesta 2, 10000 Zagreb, Croatia

Zip Code :

City :

Country : Croatia

Email : tzorbaz@imi.hr

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References (13)

Title : Cytotoxicity-related effects of imidazolium and chlorinated bispyridinium oximes in SH-SY5Y cells - Zandona_2022_Arh.Hig.Rada.Toksikol_73_277
Author(s) : Zandona A , Zorbaz T , Mis K , Pirkmajer S , Katalinic M
Ref : Arh Hig Rada Toksikol , 73 :277 , 2022
PubMedID: 36607726

Title : Halogen substituents enhance oxime nucleophilicity for reactivation of cholinesterases inhibited by nerve agents - Zorbaz_2022_Eur.J.Med.Chem_238_114377
Author(s) : Zorbaz T , Malinak D , Hofmanova T , Marakovic N , Zunec S , Hrvat NM , Andrys R , Psotka M , Zandona A , Svobodova J , Prchal L , Fingler S , Katalinic M , Kovarik Z , Musilek K
Ref : Eur Journal of Medicinal Chemistry , 238 :114377 , 2022
PubMedID: 35526478

Title : Cholinergic blockade of neuroinflammation: from tissue to RNA regulators - Zorbaz_2022_Neuronal.Signal_6_NS20210035
Author(s) : Zorbaz T , Madrer N , Soreq H
Ref : Neuronal Signal , 6 :NS20210035 , 2022
PubMedID: 35211331

Title : Altered levels of variant cholinesterase transcripts contribute to the imbalanced cholinergic signaling in Alzheimer's and Parkinson's disease - Gok_2022_Front.Mol.Neurosci_15_941467
Author(s) : Gok M , Madrer N , Zorbaz T , Bennett ER , Greenberg D , Bennett DA , Soreq H
Ref : Front Mol Neurosci , 15 :941467 , 2022
PubMedID: 36117917

Title : Pharmacokinetic evaluation of brain penetrating morpholine-3-hydroxy-2-pyridine oxime as an antidote for nerve agent poisoning - Zorbaz_2020_ACS.Chem.Neurosci__
Author(s) : Zorbaz T , Misetic P , Probst N , Zunec S , Zandona A , Mendas G , Micek V , Macek Hrvat N , Katalinic M , Braiki A , Jean L , Renard PY , Gabelica Markovic V , Kovarik Z
Ref : ACS Chem Neurosci , : , 2020
PubMedID: 32105443

Title : Butyrylcholinesterase inhibited by nerve agents is efficiently reactivated with chlorinated pyridinium oximes - Zorbaz_2019_Chem.Biol.Interact_13ChEPon_307_16
Author(s) : Zorbaz T , Malinak D , Kuca K , Musilek K , Kovarik Z
Ref : Chemico-Biological Interactions , 307 :16 , 2019
PubMedID: 31004594

Title : Reversal of Tabun Toxicity Enabled by a Triazole-Annulated Oxime Library-Reactivators of Acetylcholinesterase - Kovarik_2019_Chemistry_25_4100
Author(s) : Kovarik Z , Kalisiak J , Hrvat NM , Katalinic M , Zorbaz T , Zunec S , Green C , Radic Z , Fokin VV , Sharpless KB , Taylor P
Ref : Chemistry , 25 :4100 , 2019
PubMedID: 30458057

Title : Counteracting tabun inhibition by reactivation by pyridinium aldoximes that interact with active center gorge mutants of acetylcholinesterase - Kovarik_2019_Toxicol.Appl.Pharmacol_372_40
Author(s) : Kovarik Z , Macek Hrvat N , Kalisiak J , Katalinic M , Sit RK , Zorbaz T , Radic Z , Fokin VV , Sharpless KB , Taylor P
Ref : Toxicol Appl Pharmacol , 372 :40 , 2019
PubMedID: 30978400
Gene_locus related to this paper: human-ACHE

Title : Potent 3-Hydroxy-2-Pyridine Aldoxime Reactivators of Organophosphate-Inhibited Cholinesterases with Predicted Blood-Brain Barrier Penetration - Zorbaz_2018_Chemistry_24_9675
Author(s) : Zorbaz T , Braiki A , Marakovic N , Renou J , De la Mora E , Macek Hrvat N , Katalinic M , Silman I , Sussman JL , Mercey G , Gomez C , Mougeot R , Perez B , Baati R , Nachon F , Weik M , Jean L , Kovarik Z , Renard PY
Ref : Chemistry , 24 :9675 , 2018
PubMedID: 29672968
Gene_locus related to this paper: torca-ACHE

Title : Pyridinium Oximes with Ortho-Positioned Chlorine Moiety Exhibit Improved Physicochemical Properties and Efficient Reactivation of Human Acetylcholinesterase Inhibited by Several Nerve Agents - Zorbaz_2018_J.Med.Chem_61_10753
Author(s) : Zorbaz T , Malinak D , Marakovic N , Macek Hrvat N , Zandona A , Novotny M , Skarka A , Andrys R , Benkova M , Soukup O , Katalinic M , Kuca K , Kovarik Z , Musilek K
Ref : Journal of Medicinal Chemistry , 61 :10753 , 2018
PubMedID: 30383374

Title : Oxime-assisted reactivation of tabun-inhibited acetylcholinesterase analysed by active site mutations - Katalinic_2018_Toxicology_406-407_104
Author(s) : Katalinic M , Sinko G , Macek Hrvat N , Zorbaz T , Bosak A , Kovarik Z
Ref : Toxicology , 406-407 :104 , 2018
PubMedID: 29772260

Title : The estimation of oxime efficiency is affected by the experimental design of phosphylated acetylcholinesterase reactivation - Macek Hrvat_2018_Toxicol.Lett_293_222
Author(s) : Macek Hrvat N , Zorbaz T , Sinko G , Kovarik Z
Ref : Toxicol Lett , 293 :222 , 2018
PubMedID: 29180286

Title : New Cinchona Oximes Evaluated as Reactivators of Acetylcholinesterase and Butyrylcholinesterase Inhibited by Organophosphorus Compounds - Katalinic_2017_Molecules_22_
Author(s) : Katalinic M , Zandona A , Ramic A , Zorbaz T , Primozic I , Kovarik Z
Ref : Molecules , 22 : , 2017
PubMedID: 28737687