Macek Hrvat N

General

Full name : Macek Hrvat Nikolina

First name : Nikolina

Mail : Institute for Medical Research and Occupational Health\; Ksaverska cesta 2\; HR-10000 Zagreb

Zip Code :

City :

Country : Croatia

Email : nmacek@imi.hr

Phone : +38514673188

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Website :

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References (16)

Title : Recent advances in cholinergic mechanisms as reactions to toxicity, stress, and neuroimmune insults - Kovarik_2023_J.Neurochem_17thISCM_
Author(s) : Kovarik Z , Moshitzky G , Macek Hrvat N , Soreq H
Ref : Journal of Neurochemistry , : , 2023
PubMedID: 37429600

Title : Redistribution of gangliosides accompanies thermally induced Na(+), K(+)-ATPase activity alternation and submembrane localisation in mouse brain -
Author(s) : Puljko B , Stojanovic M , Ilic K , Macek Hrvat N , Zovko A , Damjanovic V , Mlinac-Jerkovic K , Kalanj-Bognar S
Ref : Biochimica & Biophysica Acta Biomembr , 1863 :183475 , 2021
PubMedID: 32956659

Title : Design, synthesis and cholinesterase inhibitory properties of new oxazole benzylamine derivatives - Sagud_2020_J.Enzyme.Inhib.Med.Chem_35_460
Author(s) : Sagud I , Macek Hrvat N , Grgicevic A , Cadez T , Hodak J , Dragojevic M , Lasic K , Kovarik Z , Skoric I
Ref : J Enzyme Inhib Med Chem , 35 :460 , 2020
PubMedID: 31899981

Title : Pharmacokinetic evaluation of brain penetrating morpholine-3-hydroxy-2-pyridine oxime as an antidote for nerve agent poisoning - Zorbaz_2020_ACS.Chem.Neurosci__
Author(s) : Zorbaz T , Misetic P , Probst N , Zunec S , Zandona A , Mendas G , Micek V , Macek Hrvat N , Katalinic M , Braiki A , Jean L , Renard PY , Gabelica Markovic V , Kovarik Z
Ref : ACS Chem Neurosci , : , 2020
PubMedID: 32105443

Title : Evaluation of high-affinity phenyltetrahydroisoquinoline aldoximes, linked through anti-triazoles, as reactivators of phosphylated cholinesterases - Macek Hrvat_2019_Toxicol.Lett_321_83
Author(s) : Macek Hrvat N , Kalisiak J , Sinko G , Radic Z , Sharpless KB , Taylor P , Kovarik Z
Ref : Toxicol Lett , 321 :83 , 2019
PubMedID: 31863869

Title : Counteracting tabun inhibition by reactivation by pyridinium aldoximes that interact with active center gorge mutants of acetylcholinesterase - Kovarik_2019_Toxicol.Appl.Pharmacol_372_40
Author(s) : Kovarik Z , Macek Hrvat N , Kalisiak J , Katalinic M , Sit RK , Zorbaz T , Radic Z , Fokin VV , Sharpless KB , Taylor P
Ref : Toxicol Appl Pharmacol , 372 :40 , 2019
PubMedID: 30978400
Gene_locus related to this paper: human-ACHE

Title : Potent 3-Hydroxy-2-Pyridine Aldoxime Reactivators of Organophosphate-Inhibited Cholinesterases with Predicted Blood-Brain Barrier Penetration - Zorbaz_2018_Chemistry_24_9675
Author(s) : Zorbaz T , Braiki A , Marakovic N , Renou J , De la Mora E , Macek Hrvat N , Katalinic M , Silman I , Sussman JL , Mercey G , Gomez C , Mougeot R , Perez B , Baati R , Nachon F , Weik M , Jean L , Kovarik Z , Renard PY
Ref : Chemistry , 24 :9675 , 2018
PubMedID: 29672968
Gene_locus related to this paper: torca-ACHE

Title : Pyridinium Oximes with Ortho-Positioned Chlorine Moiety Exhibit Improved Physicochemical Properties and Efficient Reactivation of Human Acetylcholinesterase Inhibited by Several Nerve Agents - Zorbaz_2018_J.Med.Chem_61_10753
Author(s) : Zorbaz T , Malinak D , Marakovic N , Macek Hrvat N , Zandona A , Novotny M , Skarka A , Andrys R , Benkova M , Soukup O , Katalinic M , Kuca K , Kovarik Z , Musilek K
Ref : Journal of Medicinal Chemistry , 61 :10753 , 2018
PubMedID: 30383374

Title : Oxime-assisted reactivation of tabun-inhibited acetylcholinesterase analysed by active site mutations - Katalinic_2018_Toxicology_406-407_104
Author(s) : Katalinic M , Sinko G , Macek Hrvat N , Zorbaz T , Bosak A , Kovarik Z
Ref : Toxicology , 406-407 :104 , 2018
PubMedID: 29772260

Title : The estimation of oxime efficiency is affected by the experimental design of phosphylated acetylcholinesterase reactivation - Macek Hrvat_2018_Toxicol.Lett_293_222
Author(s) : Macek Hrvat N , Zorbaz T , Sinko G , Kovarik Z
Ref : Toxicol Lett , 293 :222 , 2018
PubMedID: 29180286

Title : Pharmacology, Pharmacokinetics, and Tissue Disposition of Zwitterionic Hydroxyiminoacetamido Alkylamines as Reactivating Antidotes for Organophosphate Exposure - Sit_2018_J.Pharmacol.Exp.Ther_367_363
Author(s) : Sit RK , Kovarik Z , Macek Hrvat N , Zunec S , Green C , Fokin VV , Sharpless KB , Radic Z , Taylor P
Ref : Journal of Pharmacology & Experimental Therapeutics , 367 :363 , 2018
PubMedID: 30190337

Title : A comprehensive evaluation of novel oximes in creation of butyrylcholinesterase-based nerve agent bioscavengers - Katalinic_2016_Toxicol.Appl.Pharmacol_310_195
Author(s) : Katalinic M , Macek Hrvat N , Baumann K , Morasi Pipercic S , Makaric S , Tomic S , Jovic O , Hrenar T , Milicevic A , Jelic D , Zunec S , Primozic I , Kovarik Z
Ref : Toxicol Appl Pharmacol , 310 :195 , 2016
PubMedID: 27654152

Title : HI-6 assisted catalytic scavenging of VX by acetylcholinesterase choline binding site mutants - Macek Hrvat_2016_Chem.Biol.Interact_259_148
Author(s) : Macek Hrvat N , Zunec S , Taylor P , Radic Z , Kovarik Z
Ref : Chemico-Biological Interactions , 259 :148 , 2016
PubMedID: 27083141
Gene_locus related to this paper: human-ACHE

Title : Catalytic Soman Scavenging by the Y337A\/F338A Acetylcholinesterase Mutant Assisted with Novel Site-Directed Aldoximes - Kovarik_2015_Chem.Res.Toxicol_28_1036
Author(s) : Kovarik Z , Macek Hrvat N , Katalinic M , Sit RK , Paradyse A , Zunec S , Musilek K , Fokin VV , Taylor P , Radic Z
Ref : Chemical Research in Toxicology , 28 :1036 , 2015
PubMedID: 25835984

Title : Translation of in vitro to in vivo pyridinium oxime potential in tabun poisoning - Katalinic_2015_Arh.Hig.Rada.Toksikol_66_291
Author(s) : Katalinic M , Macek Hrvat N , Karasova JZ , Misik J , Kovarik Z
Ref : Arh Hig Rada Toksikol , 66 :291 , 2015
PubMedID: 26751861

Title : Centrally acting oximes in reactivation of tabun-phosphoramidated AChE - Kovarik_2013_Chem.Biol.Interact_203_77
Author(s) : Kovarik Z , Macek Hrvat N , Sit RK , Radic Z , Fokin VV , Sharpless KB , Taylor P
Ref : Chemico-Biological Interactions , 203 :77 , 2013
PubMedID: 22960624