Zunec S

General

Full name : Zunec Suzana (Berend Suzana)

First name : Suzana

Mail : Toxicology Unit, Institute for Medical Research and Occupational Health, Ksaverska C. 2, HR-10000, Zagreb

Zip Code :

City :

Country : Croatia

Email : suzana.zunec@imi.hr

Phone :

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References (34)

Title : Profiling Novel Quinuclidine-Based Derivatives as Potential Anticholinesterase Drugs: Enzyme Inhibition and Effects on Cell Viability - Zunec_2023_Int.J.Mol.Sci_25_155
Author(s) : Zunec S , Vadlja D , Ramic A , Zandona A , Marakovic N , Brekalo I , Primozic I , Katalinic M
Ref : Int J Mol Sci , 25 :155 , 2023
PubMedID: 38203326

Title : Effects of concomitant use of THC and irinotecan on tumour growth and biochemical markers in a syngeneic mouse model of colon cancer - Zunec_2023_Arh.Hig.Rada.Toksikol_74_198
Author(s) : Zunec S , Karaconji IB , Catalinac M , Juric A , Katic A , Kozina G , Micek V , Neuberg M , Vrdoljak AL
Ref : Arh Hig Rada Toksikol , 74 :198 , 2023
PubMedID: 37791673

Title : Evaluation of 4-aminoquinoline derivatives with an n-octylamino spacer as potential multi-targeting ligands for the treatment of Alzheimer's disease - Matosevic_2023_Chem.Biol.Interact_14ChEPon_382_110620
Author(s) : Matosevic A , Opsenica DM , Spasic M , Marakovic N , Zandona A , Zunec S , Bartolic M , Kovarik Z , Bosak A
Ref : Chemico-Biological Interactions , 382 :110620 , 2023
PubMedID: 37406982

Title : 4-Aminoquinoline-Based Adamantanes as Potential Anticholinesterase Agents in Symptomatic Treatment of Alzheimer's Disease - Komatovic_2022_Pharmaceutics_14_
Author(s) : Komatovic K , Matosevic A , Terzic-Jovanovic N , Zunec S , Segan S , Zlatovic M , Marakovic N , Bosak A , Opsenica DM
Ref : Pharmaceutics , 14 : , 2022
PubMedID: 35745878

Title : Halogen substituents enhance oxime nucleophilicity for reactivation of cholinesterases inhibited by nerve agents - Zorbaz_2022_Eur.J.Med.Chem_238_114377
Author(s) : Zorbaz T , Malinak D , Hofmanova T , Marakovic N , Zunec S , Hrvat NM , Andrys R , Psotka M , Zandona A , Svobodova J , Prchal L , Fingler S , Katalinic M , Kovarik Z , Musilek K
Ref : Eur Journal of Medicinal Chemistry , 238 :114377 , 2022
PubMedID: 35526478

Title : Evaluation of Toxic Effects Induced by Sub-Acute Exposure to Low Doses of alpha-Cypermethrin in Adult Male Rats - Kasuba_2022_Toxics_10_
Author(s) : Kasuba V , Tariba Lovakovic B , Lucic Vrdoljak A , Katic A , Kopjar N , Micek V , Milic M , Pizent A , Zeljezic D , Zunec S
Ref : Toxics , 10 : , 2022
PubMedID: 36548550

Title : Effects of low-level imidacloprid oral exposure on cholinesterase activity, oxidative stress responses, and primary DNA damage in the blood and brain of male Wistar rats - Katic_2020_Chem.Biol.Interact__109287
Author(s) : Katic A , Kasuba V , Kopjar N , Lovakovic BT , Marjanovic Cermak AM , Mendas G , Micek V , Milic M , Pavicic I , Pizent A , Zunec S , Zeljezic D
Ref : Chemico-Biological Interactions , :109287 , 2020
PubMedID: 33129804

Title : Pharmacokinetic evaluation of brain penetrating morpholine-3-hydroxy-2-pyridine oxime as an antidote for nerve agent poisoning - Zorbaz_2020_ACS.Chem.Neurosci__
Author(s) : Zorbaz T , Misetic P , Probst N , Zunec S , Zandona A , Mendas G , Micek V , Macek Hrvat N , Katalinic M , Braiki A , Jean L , Renard PY , Gabelica Markovic V , Kovarik Z
Ref : ACS Chem Neurosci , : , 2020
PubMedID: 32105443

Title : DNA Damaging Effects, Oxidative Stress Responses and Cholinesterase Activity in Blood and Brain of Wistar Rats Exposed to Delta(9)-Tetrahydrocannabinol - Kopjar_2019_Molecules_24_
Author(s) : Kopjar N , Fuchs N , Zunec S , Mikolic A , Micek V , Kozina G , Lucic Vrdoljak A , Brcic Karaconji I
Ref : Molecules , 24 : , 2019
PubMedID: 31010235

Title : Reversal of Tabun Toxicity Enabled by a Triazole-Annulated Oxime Library-Reactivators of Acetylcholinesterase - Kovarik_2019_Chemistry_25_4100
Author(s) : Kovarik Z , Kalisiak J , Hrvat NM , Katalinic M , Zorbaz T , Zunec S , Green C , Radic Z , Fokin VV , Sharpless KB , Taylor P
Ref : Chemistry , 25 :4100 , 2019
PubMedID: 30458057

Title : Oxidative stress, cholinesterase activity, and DNA damage in the liver, whole blood, and plasma of Wistar rats following a 28-day exposure to glyphosate - Milic_2018_Arh.Hig.Rada.Toksikol_69_154
Author(s) : Milic M , Zunec S , Micek V , Kasuba V , Mikolic A , Lovakovic BT , Semren TZ , Pavicic I , Cermak AMM , Pizent A , Vrdoljak AL , Valencia-Quintana R , Sanchez-Alarcon J , Zeljezic D
Ref : Arh Hig Rada Toksikol , 69 :154 , 2018
PubMedID: 29990293

Title : Pharmacology, Pharmacokinetics, and Tissue Disposition of Zwitterionic Hydroxyiminoacetamido Alkylamines as Reactivating Antidotes for Organophosphate Exposure - Sit_2018_J.Pharmacol.Exp.Ther_367_363
Author(s) : Sit RK , Kovarik Z , Macek Hrvat N , Zunec S , Green C , Fokin VV , Sharpless KB , Radic Z , Taylor P
Ref : Journal of Pharmacology & Experimental Therapeutics , 367 :363 , 2018
PubMedID: 30190337

Title : Evaluation of chlorpyrifos toxicity through a 28-day study: Cholinesterase activity, oxidative stress responses, parent compound\/metabolite levels, and primary DNA damage in blood and brain tissue of adult male Wistar rats - Kopjar_2017_Chem.Biol.Interact_279_51
Author(s) : Kopjar N , Zunec S , Mendas G , Micek V , Kasuba V , Mikolic A , Lovakovic BT , Milic M , Pavicic I , Cermak AMM , Pizent A , Lucic Vrdoljak A , Zeljezic D
Ref : Chemico-Biological Interactions , 279 :51 , 2017
PubMedID: 29108776

Title : A comprehensive evaluation of novel oximes in creation of butyrylcholinesterase-based nerve agent bioscavengers - Katalinic_2016_Toxicol.Appl.Pharmacol_310_195
Author(s) : Katalinic M , Macek Hrvat N , Baumann K , Morasi Pipercic S , Makaric S , Tomic S , Jovic O , Hrenar T , Milicevic A , Jelic D , Zunec S , Primozic I , Kovarik Z
Ref : Toxicol Appl Pharmacol , 310 :195 , 2016
PubMedID: 27654152

Title : HI-6 assisted catalytic scavenging of VX by acetylcholinesterase choline binding site mutants - Macek Hrvat_2016_Chem.Biol.Interact_259_148
Author(s) : Macek Hrvat N , Zunec S , Taylor P , Radic Z , Kovarik Z
Ref : Chemico-Biological Interactions , 259 :148 , 2016
PubMedID: 27083141
Gene_locus related to this paper: human-ACHE

Title : Catalytic Soman Scavenging by the Y337A\/F338A Acetylcholinesterase Mutant Assisted with Novel Site-Directed Aldoximes - Kovarik_2015_Chem.Res.Toxicol_28_1036
Author(s) : Kovarik Z , Macek Hrvat N , Katalinic M , Sit RK , Paradyse A , Zunec S , Musilek K , Fokin VV , Taylor P , Radic Z
Ref : Chemical Research in Toxicology , 28 :1036 , 2015
PubMedID: 25835984

Title : Effects of simvastatin on malondialdehyde level and esterase activity in plasma and tissue of normolipidemic rats - Macan_2015_Pharmacol.Rep_67_907
Author(s) : Macan M , Vuksic A , Zunec S , Konjevoda P , Lovric J , Kelava M , Stambuk N , Vrkic N , Bradamante V
Ref : Pharmacol Rep , 67 :907 , 2015
PubMedID: 26398384

Title : In vivo evaluation of cholinesterase activity, oxidative stress markers, cyto- and genotoxicity of K048 oxime-a promising antidote against organophosphate poisoning - Zunec_2014_Basic.Clin.Pharmacol.Toxicol_114_344
Author(s) : Zunec S , Kopjar N , Zeljezic D , Kuca K , Musilek K , Lucic Vrdoljak A
Ref : Basic Clin Pharmacol Toxicol , 114 :344 , 2014
PubMedID: 24741714

Title : Mechanism of interaction of novel uncharged, centrally active reactivators with OP-hAChE conjugates - Radic_2013_Chem.Biol.Interact_203_67
Author(s) : Radic Z , Sit RK , Garcia E , Zhang LM , Zunec S , Kovarik Z , Amitai G , Fokin VV , Sharpless KB , Taylor P
Ref : Chemico-Biological Interactions , 203 :67 , 2013
PubMedID: 22975155

Title : Catalytic detoxification of nerve agent and pesticide organophosphates by butyrylcholinesterase assisted with non-pyridinium oximes - Radic_2013_Biochem.J_450_231
Author(s) : Radic Z , Dale T , Kovarik Z , Zunec S , Garcia E , Zhang LM , Amitai G , Green C , Radic B , Duggan BM , Ajami D , Rebek J , Taylor P
Ref : Biochemical Journal , 450 :231 , 2013
PubMedID: 23216060

Title : Refinement of structural leads for centrally acting oxime reactivators of phosphylated cholinesterases - Radic_2012_J.Biol.Chem_287_11798
Author(s) : Radic Z , Sit RK , Kovarik Z , Zunec S , Garcia E , Zhang L , Amitai G , Green C , Radic B , Fokin VV , Sharpless KB , Taylor P
Ref : Journal of Biological Chemistry , 287 :11798 , 2012
PubMedID: 22343626

Title : A conjugate of pyridine-4-aldoxime and atropine as a potential antidote against organophosphorus compounds poisoning - Lovric_2011_Acta.Biochim.Pol_58_193
Author(s) : Lovric J , Zunec S , Lucic Vrdoljak A , Radic B , Katalinic M , Kovarik Z , Zeljezic D , Kopjar N , Rast S , Mesic M
Ref : Acta Biochim Pol , 58 :193 , 2011
PubMedID: 21666889

Title : In vivo experimental approach to treatment against tabun poisoning - Berend_2010_J.Enzyme.Inhib.Med.Chem_25_531
Author(s) : Zunec S , Katalinic M , Vrdoljak AL , Kovarik Z , Kuca K , Radic B
Ref : J Enzyme Inhib Med Chem , 25 :531 , 2010
PubMedID: 20235800

Title : The antidotal efficacy of the bispyridinium oximes K027 and TMB-4 against tabun poisoning in mice - Berend_2010_Chem.Biol.Interact_187_291
Author(s) : Zunec S , Radic B , Kuca K , Lucic Vrdoljak A
Ref : Chemico-Biological Interactions , 187 :291 , 2010
PubMedID: 20138854

Title : Evaluation of oxime k203 as antidote in tabun poisoning - Kovarik_2009_Arh.Hig.Rada.Toksikol_60_19
Author(s) : Kovarik Z , Vrdoljak AL , Zunec S , Katalinic M , Kuc K , Musilek K , Radic B
Ref : Arh Hig Rada Toksikol , 60 :19 , 2009
PubMedID: 19329372

Title : Evaluation of genome damage and its relation to oxidative stress induced by glyphosate in human lymphocytes in vitro - Mladinic_2009_Environ.Mol.Mutagen_50_800
Author(s) : Mladinic M , Zunec S , Vrdoljak AL , Kopjar N , Radic B , Zeljezic D
Ref : Environmental & Molecular Mutagenesis , 50 :800 , 2009
PubMedID: 19402152

Title : Irinotecan side effects relieved by the use of HI-6 oxime: in vivo experimental approach - Vrdoljak_2009_Basic.Clin.Pharmacol.Toxicol_105_401
Author(s) : Vrdoljak AL , Zunec S , Zeljezic D , Piljac-Zegarac J , Plestina S , Kuca K , Radic B , Mladinic M , Kopjar N
Ref : Basic Clin Pharmacol Toxicol , 105 :401 , 2009
PubMedID: 19663821

Title : Tenocyclidine treatment in soman-poisoned rats--intriguing results on genotoxicity versus protection - Petek_2008_Acta.Biochim.Pol_55_97
Author(s) : Petek MJ , Zunec S , Kopjar N , Zeljezic D , Mladinic M , Radic B , Vrdoljak AL
Ref : Acta Biochim Pol , 55 :97 , 2008
PubMedID: 18324340

Title : New bispyridinium oximes: in vitro and in vivo evaluation of their biological efficiency in soman and tabun poisoning - Berend_2008_Chem.Biol.Interact_175_413
Author(s) : Zunec S , Vrdoljak AL , Radic B , Kuca K
Ref : Chemico-Biological Interactions , 175 :413 , 2008
PubMedID: 18547553

Title : Oximes: Reactivators of phosphorylated acetylcholinesterase and antidotes in therapy against tabun poisoning - Kovarik_2008_Chem.Biol.Interact_175_173
Author(s) : Kovarik Z , Calic M , Sinko G , Bosak A , Zunec S , Vrdoljak AL , Radic B
Ref : Chemico-Biological Interactions , 175 :173 , 2008
PubMedID: 18501341

Title : [Determination of total polyphenol content in food with the flow-injection method] - Berend_2008_Arh.Hig.Rada.Toksikol_59_205
Author(s) : Zunec S , Grabaric Z
Ref : Arh Hig Rada Toksikol , 59 :205 , 2008
PubMedID: 18812280

Title : Evaluation of HI-6 oxime: potential use in protection of human acetylcholinesterase inhibited by antineoplastic drug irinotecan and its cyto\/genotoxicity in vitro - Radic_2007_Acta.Biochim.Pol_54_583
Author(s) : Radic B , Vrdoljak AL , Zeljezic D , Fuchs N , Zunec S , Kopjar N
Ref : Acta Biochim Pol , 54 :583 , 2007
PubMedID: 17713603

Title : Comparative evaluation of acetylcholinesterase status and genome damage in blood cells of industrial workers exposed to carbofuran - Zeljezic_2007_Food.Chem.Toxicol_45_2488
Author(s) : Zeljezic D , Vrdoljak AL , Radic B , Fuchs N , Zunec S , Orescanin V , Kopjar N
Ref : Food & Chemical Toxicology , 45 :2488 , 2007
PubMedID: 17673351

Title : Pretreatment with pyridinium oximes improves antidotal therapy against tabun poisoning - Lucic_2006_Toxicology_228_41
Author(s) : Lucic Vrdoljak A , Calic M , Radic B , Zunec S , Jun D , Kuca K , Kovarik Z
Ref : Toxicology , 228 :41 , 2006
PubMedID: 16982122