Title : Radiosynthesis and evaluation of novel (18)F labeled PET ligands for imaging monoacylglycerol lipase - Li_2025_Eur.J.Med.Chem_285_117246 |
Author(s) : Li Y , Mori W , Chaudhary A , Zhao C , Yamasaki T , Zhang Z , Feng S , Ware T , Rong J , Fujinaga M , Chen J , Kumata K , Zhang Y , Hu K , Xie L , Zhou X , Song Z , Gao Y , Sun Z , Patel JS , Zhai C , Yuan KY , Collier TL , Ran C , Collin L , Haider A , Grether U , Wittwer MB , Cravatt BF , Zhang MR , Liang SH |
Ref : Eur Journal of Medicinal Chemistry , 285 :117246 , 2025 |
Abstract : |
PubMedSearch : Li_2025_Eur.J.Med.Chem_285_117246 |
PubMedID: 39793441 |
Gene_locus related to this paper: human-MGLL |
Title : [(18)F]MAGL-4-11 positron emission tomography molecular imaging of monoacylglycerol lipase changes in preclinical liver fibrosis models - Shao_2022_Acta.Pharm.Sin.B_12_308 |
Author(s) : Shao T , Chen Z , Rong J , Belov V , Chen J , Jeyarajan A , Deng X , Fu H , Yu Q , Rwema SH , Lin W , Papisov M , Josephson L , Chung RT , Liang SH |
Ref : Acta Pharm Sin B , 12 :308 , 2022 |
Abstract : |
PubMedSearch : Shao_2022_Acta.Pharm.Sin.B_12_308 |
PubMedID: 35127387 |
Title : A novel monoacylglycerol lipase-targeted (18)F-labeled probe for positron emission tomography imaging of brown adipose tissue in the energy network - Cheng_2022_Acta.Pharmacol.Sin__ |
Author(s) : Cheng R , Fujinaga M , Yang J , Rong J , Haider A , Ogasawara D , Van RS , Shao T , Chen Z , Zhang X , Calderon Leon ER , Zhang Y , Mori W , Kumata K , Yamasaki T , Xie L , Sun S , Wang L , Ran C , Shao Y , Cravatt B , Josephson L , Zhang MR , Liang SH |
Ref : Acta Pharmacol Sin , : , 2022 |
Abstract : |
PubMedSearch : Cheng_2022_Acta.Pharmacol.Sin__ |
PubMedID: 35513432 |
Gene_locus related to this paper: human-MGLL |
Title : Positron Emission Tomography Imaging of the Endocannabinoid System: Opportunities and Challenges in Radiotracer Development - Hou_2021_J.Med.Chem_64_123 |
Author(s) : Hou L , Rong J , Haider A , Ogasawara D , Varlow C , Schafroth MA , Mu L , Gan J , Xu H , Fowler CJ , Zhang MR , Vasdev N , Ametamey S , Cravatt BF , Wang L , Liang SH |
Ref : Journal of Medicinal Chemistry , 64 :123 , 2021 |
Abstract : |
PubMedSearch : Hou_2021_J.Med.Chem_64_123 |
PubMedID: 33379862 |
Title : Novel Reversible-Binding PET Ligands for Imaging Monoacylglycerol Lipase Based on the Piperazinyl Azetidine Scaffold - Rong_2021_J.Med.Chem__ |
Author(s) : Rong J , Mori W , Xia X , Schafroth MA , Zhao C , Van RS , Yamasaki T , Chen J , Xiao Z , Haider A , Ogasawara D , Hiraishi A , Shao T , Zhang Y , Chen Z , Pang F , Hu K , Xie L , Fujinaga M , Kumata K , Gou Y , Fang Y , Gu S , Wei H , Bao L , Xu H , Collier TL , Shao Y , Carson RE , Cravatt BF , Wang L , Zhang MR , Liang SH |
Ref : Journal of Medicinal Chemistry , : , 2021 |
Abstract : |
PubMedSearch : Rong_2021_J.Med.Chem__ |
PubMedID: 34569803 |
Gene_locus related to this paper: human-MGLL |
Title : Development of a highly-specific (18)F-labeled irreversible positron emission tomography tracer for monoacylglycerol lipase mapping - Chen_2021_Acta.Pharm.Sin.B_11_1686 |
Author(s) : Chen Z , Mori W , Rong J , Schafroth MA , Shao T , Van RS , Ogasawara D , Yamasaki T , Hiraishi A , Hatori A , Chen J , Zhang Y , Hu K , Fujinaga M , Sun J , Yu Q , Collier TL , Shao Y , Cravatt BF , Josephson L , Zhang MR , Liang SH |
Ref : Acta Pharm Sin B , 11 :1686 , 2021 |
Abstract : |
PubMedSearch : Chen_2021_Acta.Pharm.Sin.B_11_1686 |
PubMedID: 34221877 |
Gene_locus related to this paper: human-MGLL |
Title : Design, Synthesis, and Evaluation of (18)F-Labeled Monoacylglycerol Lipase Inhibitors as Novel Positron Emission Tomography Probes - Chen_2019_J.Med.Chem_62_8866 |
Author(s) : Chen Z , Mori W , Fu H , Schafroth MA , Hatori A , Shao T , Zhang G , Van RS , Zhang Y , Hu K , Fujinaga M , Wang L , Belov V , Ogasawara D , Giffenig P , Deng X , Rong J , Yu Q , Zhang X , Papisov MI , Shao Y , Collier TL , Ma JA , Cravatt BF , Josephson L , Zhang MR , Liang SH |
Ref : Journal of Medicinal Chemistry , 62 :8866 , 2019 |
Abstract : |
PubMedSearch : Chen_2019_J.Med.Chem_62_8866 |
PubMedID: 31518130 |
Title : Design, Synthesis, and Evaluation of Reversible and Irreversible Monoacylglycerol Lipase Positron Emission Tomography (PET) Tracers Using a Tail Switching Strategy on a Piperazinyl Azetidine Skeleton - Chen_2019_J.Med.Chem_62_3336 |
Author(s) : Chen Z , Mori W , Deng X , Cheng R , Ogasawara D , Zhang G , Schafroth MA , Dahl K , Fu H , Hatori A , Shao T , Zhang Y , Yamasaki T , Zhang X , Rong J , Yu Q , Hu K , Fujinaga M , Xie L , Kumata K , Gou Y , Chen J , Gu S , Bao L , Wang L , Collier TL , Vasdev N , Shao Y , Ma JA , Cravatt BF , Fowler C , Josephson L , Zhang MR , Liang SH |
Ref : Journal of Medicinal Chemistry , 62 :3336 , 2019 |
Abstract : |
PubMedSearch : Chen_2019_J.Med.Chem_62_3336 |
PubMedID: 30829483 |
Gene_locus related to this paper: human-MGLL |
Title : First demonstration of in vivo mapping for regional brain monoacylglycerol lipase using PET with [(11)C]SAR127303 - Yamasaki_2018_Neuroimage_176_313 |
Author(s) : Yamasaki T , Mori W , Zhang Y , Hatori A , Fujinaga M , Wakizaka H , Kurihara Y , Wang L , Nengaki N , Ohya T , Liang SH , Zhang MR |
Ref : Neuroimage , 176 :313 , 2018 |
Abstract : |
PubMedSearch : Yamasaki_2018_Neuroimage_176_313 |
PubMedID: 29738910 |
Title : In Vitro and in Vivo Evaluation of (11)C-Labeled Azetidinecarboxylates for Imaging Monoacylglycerol Lipase by PET Imaging Studies - Cheng_2018_J.Med.Chem_61_2278 |
Author(s) : Cheng R , Mori W , Ma L , Alhouayek M , Hatori A , Zhang Y , Ogasawara D , Yuan G , Chen Z , Zhang X , Shi H , Yamasaki T , Xie L , Kumata K , Fujinaga M , Nagai Y , Minamimoto T , Svensson M , Wang L , Du Y , Ondrechen MJ , Vasdev N , Cravatt BF , Fowler C , Zhang MR , Liang SH |
Ref : Journal of Medicinal Chemistry , 61 :2278 , 2018 |
Abstract : |
PubMedSearch : Cheng_2018_J.Med.Chem_61_2278 |
PubMedID: 29481079 |
Title : Alternative approaches for PET radiotracer development in Alzheimer's disease: imaging beyond plaque - Holland_2014_J.Labelled.Comp.Radiopharm_57_323 |
Author(s) : Holland JP , Liang SH , Rotstein BH , Collier TL , Stephenson NA , Greguric I , Vasdev N |
Ref : J Labelled Comp Radiopharm , 57 :323 , 2014 |
Abstract : |
PubMedSearch : Holland_2014_J.Labelled.Comp.Radiopharm_57_323 |
PubMedID: 24327420 |
Title : Alternative promoters determine tissue-specific expression profiles of the human microsomal epoxide hydrolase gene (EPHX1) - Liang_2005_Mol.Pharmacol_67_220 |
Author(s) : Liang SH , Hassett C , Omiecinski CJ |
Ref : Molecular Pharmacology , 67 :220 , 2005 |
Abstract : |
PubMedSearch : Liang_2005_Mol.Pharmacol_67_220 |
PubMedID: 15465926 |
Title : Characterization of the function of the ver-1A and ver-1B genes, involved in aflatoxin biosynthesis in Aspergillus parasiticus - Liang_1996_Appl.Environ.Microbiol_62_4568 |
Author(s) : Liang SH , Skory CD , Linz JE |
Ref : Applied Environmental Microbiology , 62 :4568 , 1996 |
Abstract : |
PubMedSearch : Liang_1996_Appl.Environ.Microbiol_62_4568 |
PubMedID: 8953728 |
Gene_locus related to this paper: asppa-ESTA1.2 |