| Title : Novel tacrine-based multi-target directed Ligands: Enhancing cholinesterase inhibition, NMDA receptor antagonism, and CNS bioavailability for Alzheimer's disease treatment - Svobodova_2025_Eur.J.Med.Chem_292_117678 |
| Author(s) : Svobodova B , Moravcova Z , Misiachna A , Novakova G , Marek A , Finger V , Odvarkova J , Pejchal J , Karasova JZ , Netolicky J , Ladislav M , Hrabinova M , Sorf A , Muckova L , Fikejzlova L , Benkova M , Novak M , Prchal L , Capek J , Handl J , Rousar T , Greber KE , Ciura K , Horak M , Soukup O , Korabecny J |
| Ref : Eur Journal of Medicinal Chemistry , 292 :117678 , 2025 |
| Abstract : |
| PubMedSearch : Svobodova_2025_Eur.J.Med.Chem_292_117678 |
| PubMedID: 40288120 |
| Title : Structure-Guided Design of N-Methylpropargylamino-Quinazoline Derivatives as Multipotent Agents for the Treatment of Alzheimer's Disease - Svobodova_2023_Int.J.Mol.Sci_24_ |
| Author(s) : Svobodova B , Pulkrabkova L , Panek D , Misiachna A , Kolcheva M , Andrys R , Handl J , Capek J , Nyvltova P , Rousar T , Prchal L , Hepnarova V , Hrabinova M , Muckova L , Tosnerova D , Karabanovich G , Finger V , Soukup O , Horak M , Korabecny J |
| Ref : Int J Mol Sci , 24 : , 2023 |
| Abstract : |
| PubMedSearch : Svobodova_2023_Int.J.Mol.Sci_24_ |
| PubMedID: 37298087 |
| Title : Effects of Charged Oxime Reactivators on the HK-2 Cell Line in Renal Toxicity Screening - Handl_2021_Chem.Res.Toxicol__ |
| Author(s) : Handl J , Malinak D , Capek J , Andrys R , Rousarova E , Hauschke M , Bruckova L , Cesla P , Rousar T , Musilek K |
| Ref : Chemical Research in Toxicology , : , 2021 |
| Abstract : |
| PubMedSearch : Handl_2021_Chem.Res.Toxicol__ |
| PubMedID: 33566584 |